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  1. Pontocerebellar hypoplasia (PCH) is increasingly known as a degenerative disease rather than simple “hypoplasia”. At least 21 disease-causing genes have been identified for PCH so far. Because PCH is very hete...

    Authors: Mamiko Yamada, Hisato Suzuki, Hiroyuki Adachi, Atsuko Noguchi, Fuyuki Miya, Tsutomu Takahashi and Kenjiro Kosaki
    Citation: BMC Neurology 2022 22:20
  2. The influence of chronic kidney disease (CKD) on the severity and prognosis of spontaneous intracerebral hemorrhage (ICH) has been scarcely investigated. We aimed to explore the association of admission estima...

    Authors: Zhaoxia Li, Zixiao Li, Qi Zhou, Hongqiu Gu, Yongjun Wang and Xingquan Zhao
    Citation: BMC Neurology 2022 22:19
  3. We report the case of a patient with recurrent episodes of disturbed memory suggestive of transient epileptic amnesia, and a focal hippocampal lesion typically associated with transient global amnesia. We argu...

    Authors: Eckhard Schlemm, Tim Magnus, Leander D. Rimmele, Justine Münsterberg, Maxim Bester, Simon S. Kessner, Mathias Gelderblom and Christian Gerloff
    Citation: BMC Neurology 2022 22:18
  4. Charcot-Marie-Tooth disease (CMT) is a genetically heterogeneous hereditary neuropathy, and CMT1A is the most common form; it is caused by a duplication of the peripheral myelin protein 22 (PMP22) gene. Mutations...

    Authors: Haitian Nan, Yunqing Wu, Shilei Cui, Houliang Sun, Jiawei Wang, Ying Li, Lingchao Meng, Takamura Nagasaka and Liyong Wu
    Citation: BMC Neurology 2022 22:17
  5. Progressive haemorrhagic injury after surgery in patients with traumatic brain injury often results in poor patient outcomes. This study aimed to develop and validate a practical predictive tool that can relia...

    Authors: Tiange Chen, Siming Chen, Yun Wu, Yilei Chen, Lei Wang and Jinfang Liu
    Citation: BMC Neurology 2022 22:16
  6. An increased susceptibility to COVID-19 has been suggested for individuals with neurodegenerative diseases, but data are scarce from longitudinal studies.

    Authors: Yihan Hu, Huazhen Yang, Can Hou, Wenwen Chen, Hanyue Zhang, Zhiye Ying, Yao Hu, Yajing Sun, Yuanyuan Qu, Maria Feychting, Unnur Valdimarsdottir, Huan Song and Fang Fang
    Citation: BMC Neurology 2022 22:15
  7. Temporal lobe epilepsy (TLE) is commonly refractory. Epilepsy surgery is an effective treatment strategy for refractory epilepsy, but patients with a history of focal to bilateral tonic-clonic seizures (FBTCS)...

    Authors: Liluo Nie, Yanchun Jiang, Zongxia Lv, Xiaomin Pang, Xiulin Liang, Weiwei Chang and Jinou Zheng
    Citation: BMC Neurology 2022 22:14
  8. Parkinson’s disease (PD) is associated with enteric nervous system dysfunction and gut microbiota dysbiosis. Short-chain fatty acids (SCFAs), derived from gut microbiota, are supposed to anticipate PD pathogen...

    Authors: Gang Wu, Zhengli Jiang, Yaling Pu, Shiyong Chen, Tingling Wang, Yajing Wang, Xiaoping Xu, Shanshan Wang, Minya Jin, Yangyang Yao, Yang Liu, Shaofa Ke and Suzhi Liu
    Citation: BMC Neurology 2022 22:13
  9. Myoclonus-dystonia is a rare movement disorder with an autosomal dominant inheritance pattern characterized by a combination of myoclonic jerks and dystonia that may have psychiatric manifestations. Our aim is...

    Authors: Meliza Angelica J. de Leon, Raymond L. Rosales, Christine Klein and Ana Westenberger
    Citation: BMC Neurology 2022 22:11
  10. Leukoencephalopathy with brain calcifications and cysts (LCC; also known as Labrune syndrome) is a rare genetic microangiopathy caused by biallelic mutations in SNORD118. The mechanisms by which loss-of-function ...

    Authors: Michelle Paff, Nardin Samuel, Noor Alsafwani, Darcia Paul, Phedias Diamandis, Seth A. Climans, Walter Kucharczyk, Mandy Yi Rong Ding, Andrew F. Gao and Andres M. Lozano
    Citation: BMC Neurology 2022 22:10
  11. Guillain–Barré syndrome (GBS) and spinal epidural abscess (SEA) are known as mimics of each other because they present with flaccid paralysis following an infection; however, they differ in the main causative ...

    Authors: Masako Fujita, Tatsuya Ueno, Michiru Horiuchi, Tatsuro Mitsuhashi, Shouji Yamamoto, Akira Arai and Masahiko Tomiyama
    Citation: BMC Neurology 2022 22:9
  12. Growing evidence suggests a mutual interaction between gut microbiome alterations and ALS pathogenesis. However, previous studies were susceptible to potential confounding factors and reverse causation bias, l...

    Authors: Linjing Zhang, Zhenhuang Zhuang, Gan Zhang, Tao Huang and Dongsheng Fan
    Citation: BMC Neurology 2022 22:8
  13. Transient ischemic attack (TIA) is an important predictor for a pending stroke. Guidelines recommend a workup for TIA-patients similar to that of stroke patients, including an assessment of the extra- and intr...

    Authors: Ilko L. Maier, Gerrit U. Herpertz, Mathias Bähr, Marios-Nikos Psychogios and Jan Liman
    Citation: BMC Neurology 2022 22:7
  14. This study assessed the predictive factors for symptomatic intracranial hemorrhage (sICH) in patients with acute ischemic stroke (AIS) after receiving intravenous thrombolysis (IVT) within 6 h in northern China.

    Authors: Yuan Xue, Shan Li, Yuanyuan Xiang, Ziran Wang, Fengyun Wang, Yuanying Yu, Peng Yan, Xiaohui Liu, Qinjian Sun, Yifeng Du and Jifeng Li
    Citation: BMC Neurology 2022 22:6
  15. Sleep characteristics associated with dementia are poorly defined and whether their associations vary by demographics and APOE genotype among older adults are unclear.

    Authors: Rui Liu, Shi Tang, Yongxiang Wang, Yi Dong, Tingting Hou, Yifei Ren, Lin Cong, Keke Liu, Yu Qin, Shireen Sindi, Yifeng Du and Chengxuan Qiu
    Citation: BMC Neurology 2022 22:5
  16. Headache is one of the most disturbing complaints worldwide, negatively impacting social and regular life activities. In the background of stressful life in medical schools, adding to the stressful situation i...

    Authors: Firas Anaya, Wala’a Abu Alia, Feda’a Hamoudeh, Zaher Nazzal and Beesan Maraqa
    Citation: BMC Neurology 2022 22:4
  17. A decrease in hippocampal neurogenesis is considered an important cause of cognitive impairment, while changes in mossy fiber sprouting are closely related to development of spontaneous recurrent seizures in c...

    Authors: Shanshan Zhao, Fangxi Liu, Wei Shi, Jialu Wang, Zhike Zhou and Xiaoqian Zhang
    Citation: BMC Neurology 2022 22:3
  18. The detailed neuropathological features of patients with autosomal recessive hereditary spastic paraplegia with a thin corpus callosum (TCC) and SPG11 mutations are poorly understood, as only a few autopsies have...

    Authors: Mika Hayakawa, Tomoyasu Matsubara, Yoko Mochizuki, Chisen Takeuchi, Motoyuki Minamitani, Masayuki Imai, Kenjiro Kosaki, Tomio Arai and Shigeo Murayama
    Citation: BMC Neurology 2022 22:2
  19. This study was performed to identify the association between the total magnetic resonance imaging burden of small vessel disease and the occurrence of post-stroke dysphagia in patients with a single recent sma...

    Authors: Lulu Zhang, Xiang Tang, Yidan Li, Juehua Zhu, Dongxue Ding, Yun Zhou, Shanshan Diao, Yan Kong, Xiuying Cai, Ye Yao and Qi Fang
    Citation: BMC Neurology 2022 22:1
  20. The purpose of this study was to examine the associations between combined and individual cerebral small vessel disease (cSVD) markers on future walking speed over 9 years; and to explore whether these associa...

    Authors: Emerald G. Heiland, Anna-Karin Welmer, Grégoria Kalpouzos, Anna Laveskog, Rui Wang and Chengxuan Qiu
    Citation: BMC Neurology 2021 21:496
  21. Toscana virus (TOSV) is an arthropod-borne virus transmitted by phlebotomine sandflies (Phlebotomus sp.) widespread throughout the Mediterranean having the potential to cause meningoencephalitis in humans. In Ger...

    Authors: R. Dersch, A. Sophocleous, D. Cadar, P. Emmerich, J. Schmidt-Chanasit and S. Rauer
    Citation: BMC Neurology 2021 21:495
  22. Blood-brain barrier (BBB) injury is prevalent in patients with HIV-associated dementia (HAD) and is a frequent feature of HIV encephalitis. Signs of BBB damage are also sometimes found in neuroasymptomatic HIV...

    Authors: Birgitta Anesten, Henrik Zetterberg, Staffan Nilsson, Bruce J. Brew, Dietmar Fuchs, Richard W. Price, Magnus Gisslén and Aylin Yilmaz
    Citation: BMC Neurology 2021 21:494

    The Correction to this article has been published in BMC Neurology 2022 22:197

  23. Cranial autonomic symptoms are common in migraine, with eye redness and tearing being the most common ones. Their identification can help to avoid misdiagnosis, predict the disease course, and select the appro...

    Authors: Mansoureh Togha, Elham Jafari, Atieh Moosavian, Abolfazl Farbod, Shadi Ariyanfar and Fatemeh Farham
    Citation: BMC Neurology 2021 21:493
  24. Impaired motor function is one of the early symptoms shown in patients with Parkinson Disease (PD). For this reason, rehabilitative interventions have been used for many years to improve motor and non-motor sy...

    Authors: Patricia Abril-Jiménez, Beatriz Merino-Barbancho, Cecilia Vera-Muñoz and María Teresa Arredondo Waldmeyer
    Citation: BMC Neurology 2021 21:491
  25. Encephalitis associated with antibodies against alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) is an extremely rare type of antibody-mediated encephalitis. This research aims to inve...

    Authors: Zhe Zhang, Siyuan Fan, Haitao Ren, Lixin Zhou and Hongzhi Guan
    Citation: BMC Neurology 2021 21:490
  26. Dural chondrosarcoma is a very rare intracranial tumor, given that meninges do not normally contain cartilaginous tissue from which it can originate. We present a case of primary extraosseous dural chondrosarc...

    Authors: Francis Garay Buitron, Albert Pons-Escoda, Noemí Vidal, Alberto Torres and Angels Camins
    Citation: BMC Neurology 2021 21:489
  27. A previously shown ‘mismatch’ group of patients with good observed upper limb (UL) motor function but low perceived UL activity at six months post stroke tends to use the affected UL less in daily life than wo...

    Authors: Bea Essers, Annick Van Gils, Christophe Lafosse, Marc Michielsen, Hilde Beyens, Fabienne Schillebeeckx, Janne M. Veerbeek, Andreas R. Luft, Daphne Kos and Geert Verheyden
    Citation: BMC Neurology 2021 21:488
  28. Glycemic patterns have been reported to be prognostic factors for stroke; however, this remains to be further evaluated. This meta-analysis aimed to evaluate the usefulness of glycemic patterns such as persist...

    Authors: Duanlu Hou, Ping Zhong, Xiaofei Ye and Danhong Wu
    Citation: BMC Neurology 2021 21:487
  29. Erenumab is a calcitonin gene-related peptide (CGRP)-receptor antibody inhibiting CGRP function. CGRP is prominently involved in the pathophysiology of migraine through nociceptive modulation in the trigeminov...

    Authors: Bui Bao Khanh Dinh, Waseem Hamed Aziz, Alessandro Terruzzi and Derk Wolfgang Krieger
    Citation: BMC Neurology 2021 21:486
  30. Vaccination against COVID-19 continues apace, but side-effects, both common and severe, continue to be reported. We report here the first published case of COVID-19 vaccine-related encephalitis.

    Authors: Junko Takata, Simon M. Durkin, Solomon Wong, Michael S. Zandi, Josephine K. Swanton and Tumena W. Corrah
    Citation: BMC Neurology 2021 21:485
  31. Brain Magnetic Resonance Imaging (MRI) examination of cerebral small vessel disease (CSVD) may help screen vascular cognitive impairment. A recently estimated CSVD score system was suggested to capture the ove...

    Authors: Wei-Wen Wu, Yang Wang, Jun Xu, Li-Xia Lu, Lin Chen, Gang Wu and Hui Yu
    Citation: BMC Neurology 2021 21:484
  32. Central sensitization is an amplification of neuronal signaling within the central nervous system. The Central Sensitization Inventory was introduced in 2012. A Polish version of the CSI (CSI-Pol) was develope...

    Authors: Barbara Kosińska, Beata Tarnacka, Paweł Turczyn, Grażyna Gromadzka, Małgorzata Malec-Milewska, Dorota Janikowska-Hołowenko and Randy Neblett
    Citation: BMC Neurology 2021 21:483
  33. The development of intraventricular hemorrhage (IVH) in aneurysmal subarachnoid hemorrhage (aSAH) is linked with higher mortality and poor neurological recovery. Previous studies have investigated the effect o...

    Authors: Hae Gi Park, Sunghan Kim, Joonho Chung, Chang Ki Jang, Keun Young Park and Jae Whan Lee
    Citation: BMC Neurology 2021 21:482
  34. Cognitive impairment and depressive symptoms are highly prevalent after Intracerebral Hemorrhage (ICH). We leveraged Latent Profile Analysis (LPA) to identify profiles for cognitive decline and depression onse...

    Authors: Sophia Keins, Jessica R. Abramson, Juan Pablo Castello, Marco Pasi, Andreas Charidimou, Christina Kourkoulis, Zora DiPucchio, Kristin Schwab, Christopher D. Anderson, M. Edip Gurol, Steven M. Greenberg, Jonathan Rosand, Anand Viswanathan and Alessandro Biffi
    Citation: BMC Neurology 2021 21:481
  35. Late-stage Parkinson’s disease (PD) often presents with neuropsychiatric symptoms such as dementia, psychosis, excessive daytime sleepiness, apathy, depression, and anxiety. However, neuropsychiatric symptoms ...

    Authors: Shin-ichiro Kubo, Tomoyasu Matsubara, Takeshi Taguchi, Renpei Sengoku, Atsuko Takeuchi and Yuko Saito
    Citation: BMC Neurology 2021 21:480
  36. The diagnosis and therapy of reversible cerebral vasoconstriction syndrome (RCVS) tends to focus on neurological symptoms, but less attention has been paid the occurrence of extracerebral lesion such as the my...

    Authors: Kenya Oguchi, Kazuhiro Fukushima, Akinori Nakamura and Yo-ichi Takei
    Citation: BMC Neurology 2021 21:479
  37. Whether liver fibrosis is associated with increased risk for substantial hematoma expansion (HE) after intracerebral hemorrhage (ICH) is still uncertain. We evaluated the association between various liver fibr...

    Authors: Huan Wang, Jiongxing Wu, Xue Yang, Junfeng Liu, Wendan Tao, Zilong Hao, Bo Wu, Ming Liu, Shihong Zhang and Deren Wang
    Citation: BMC Neurology 2021 21:478
  38. Identifying modifiable risk factors for cognitive impairment in the early stages of Parkinson’s disease (PD) and estimating their impact on cognitive status may help prevent dementia (PDD) and the design of co...

    Authors: Saul Martínez-Horta, Helena Bejr-Kasem, Andrea Horta-Barba, Berta Pascual-Sedano, Diego Santos-García, Teresa de Deus-Fonticoba, Silvia Jesús, Miquel Aguilar, Lluis Planellas, Juan García-Caldentey, Nuria Caballol, Bárbara Vives-Pastor, Jorge Hernández-Vara, Iria Cabo-Lopez, Lydia López-Manzanares, Isabel González-Aramburu…
    Citation: BMC Neurology 2021 21:477
  39. Chronic low-grade inflammation is associated with both ischemic stroke and sedentary behaviour. The aim of this study was to investigate the predictive abilities of biomarkers of inflammation and immune modula...

    Authors: Katinka Nordheim Alme, Arve Ulvik, Torunn Askim, Jörg Assmus, Tom Eirik Mollnes, Mala Naik, Halvor Næss, Ingvild Saltvedt, Per-Magne Ueland and Anne-Brita Knapskog
    Citation: BMC Neurology 2021 21:476
  40. This study aims to evaluate the diagnostic performance of NIHSS extinction and inattention item, compared to the results of the Oxford Cognitive Screen (OCS) heart subtest. Additionally, the possible role of the ...

    Authors: Benedetta Basagni, Bahia Hakiki, Silvia Campagnini, Emilia Salvadori, Antonello Grippo, Anita Paperini, Chiara Castagnoli, Ines Hochleitner, Angela Maria Politi, Paola Gemignani, Irene Eleonora Mosca, Azzurra Franceschini, Enrico Bacci Bonotti, Alessandro Sodero, Andrea Mannini, Leonardo Pellicciari…
    Citation: BMC Neurology 2021 21:475
  41. Depending on geographic location, causes of encephalitis, meningoencephalitis and meningitis vary substantially. We aimed to identify the most frequent causes, clinical presentation and long-term outcome of en...

    Authors: Anamaria Ungureanu, Julia van der Meer, Antonela Bicvic, Lena Abbuehl, Gabriele Chiffi, Léonore Jaques, Franziska Suter-Riniker, Stephen L. Leib, Claudio L. A. Bassetti and Anelia Dietmann
    Citation: BMC Neurology 2021 21:474
  42. Clinical trials have shown that dexmedetomidine might decrease the occurrence of postoperative delirium after major surgery, but neurosurgical patients were excluded from these studies. We aimed to determine t...

    Authors: Xuan He, Kun-Ming Cheng, Yu-Qing Duan, Shan-Shan Xu, Hao-Ran Gao, Ming-Yue Miao, Hong-Liang Li, Kai Chen, Yan-Lin Yang, Linlin Zhang, Hong-Qiu Gu and Jian-Xin Zhou
    Citation: BMC Neurology 2021 21:472
  43. Subacute combined degeneration (SCD) is a neurological complication commonly associated with vitamin B12 deficiency. It can result from nitrous oxide (N2O) abuse and cause neuropsychiatric symptoms. However, ther...

    Authors: Jie Cao, Lusen Ran, Chenchen Liu and Zhijun Li
    Citation: BMC Neurology 2021 21:471
  44. Chronic inflammatory diseases are linked to an increased risk of stroke events. The white blood cell (WBC) count is a common marker of the inflammatory response. However, it is unclear whether the WBC count, i...

    Authors: Zhi-bing Hu, Ze-xiong Lu, Feng Zhu, Cao-qiang Jiang, Wei-sen Zhang, Jin Pan, Ya-li Jin, Lin Xu, G. Neil Thomas, Karkeung Cheng and Taihing Lam
    Citation: BMC Neurology 2021 21:470
  45. Rett syndrome (RTT) is characterized by a normal perinatal period with a normal head size at birth followed by normal development for the first 6 months of life followed by gradual deceleration of head growth,...

    Authors: Jhanvi Shah, Harsh Patel, Deepika Jain, Frenny Sheth and Harsh Sheth
    Citation: BMC Neurology 2021 21:469
  46. Multiple sclerosis (MS) is a chronic, demyelinating disease of the central nervous system that results in progressive and irreversible disability. Fatigue is one of the most common MS-related symptoms and is c...

    Authors: Abril Oliva Ramirez, Alexander Keenan, Olivia Kalau, Evelyn Worthington, Lucas Cohen and Sumeet Singh
    Citation: BMC Neurology 2021 21:468
  47. Non-dystrophic myotonias (NDMs) comprise muscle chloride and sodium channelopathies due to genetic defects of the CLCN1- and SCN4A-channels. No licensed antimyotonic treatment has been available until approval...

    Authors: Ann-Marie Chapman, Marieke Schurer, Laure Weijers, Amer Omar, Hiba Lee, Alla Zozulya Weidenfeller, Crispin Ellis, Shaneil Sonecha and Christiane Schneider-Gold
    Citation: BMC Neurology 2021 21:467

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