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  1. Although the pathology of sciatica has been studied extensively, the transcriptional changes in the peripheral blood caused by sciatica have not been characterized. This study aimed to characterize the periphe...

    Authors: Yi Wang, Guogang Dai, Ling Jiang, Shichuan Liao and Jiao Xia

    Citation: BMC Neurology 2021 21:50

    Content type: Research article

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  2. Fingolimod is a S1P1 receptor modulator that prevents activated lymphocyte egress from lymphoid tissues causing lymphopenia, mainly affecting CD4+ T lymphocytes. Withdrawal from fingolimod can be followed by seve...

    Authors: Silvia Delgado, Jeffrey Hernandez, Leticia Tornes and Kottil Rammohan

    Citation: BMC Neurology 2021 21:48

    Content type: Case report

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  3. Approximately 10% of patients would develop symptomatic intracranial hemorrhage (sICH) after endovascular therapy. The aim of our study was to explore the ability of hypersensitive C-reactive protein-albumin r...

    Authors: Qiang Peng, Jiankang Hou, Siyu Wang, Feng Zhou, Yan E, Wei Wang, Ting Huang, Meng Wang, Shi Huang, Junshan Zhou, Nihong Chen and Yingdong Zhang

    Citation: BMC Neurology 2021 21:47

    Content type: Research article

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  4. Many patients with Parkinson’s disease (PD) who receive carbidopa/levodopa experience symptom reemergence or worsening, or “OFF” episodes. This study assessed the association of “OFF” episodes with health-rela...

    Authors: Andrew Thach, Eddie Jones, Eric Pappert, James Pike, Jack Wright and Alexander Gillespie

    Citation: BMC Neurology 2021 21:46

    Content type: Research article

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  5. Endovascular procedures with liquid embolic agents such as ethylene-vinyl alcohol (EVOH) copolymers are indicated before surgical treatment of cervical paraganglioma. Consequently, these agents are now availab...

    Authors: Santiago Moreno-Paredes, Laura Rodríguez-Alcalá, Juan Martín-Lagos Martínez, Nicolás Müller Locatelli, Cristina Vázquez López, José Luis Vargas Fernández and Álvaro Cabrera Peña

    Citation: BMC Neurology 2021 21:45

    Content type: Case report

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  6. The aim of the study was to determine the role of the Coma Recovery Scale-Revised (CRS-R) in the prediction of functional status at the end of neurological early rehabilitative treatment.

    Authors: Melanie Boltzmann, Simone B. Schmidt, Christoph Gutenbrunner, Joachim K. Krauss, Martin Stangel, Günter U. Höglinger, Claus-W. Wallesch and Jens D. Rollnik

    Citation: BMC Neurology 2021 21:44

    Content type: Research article

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  7. Coronavirus disease 2019 (COVID-19) is associated with a small but clinically significant risk of stroke, the cause of which is frequently cryptogenic. In a large multinational cohort of consecutive COVID-19 p...

    Authors: María E. Ramos-Araque, James E. Siegler, Marc Ribo, Manuel Requena, Cristina López, Mercedes de Lera, Juan F. Arenillas, Isabel Hernández Pérez, Beatriz Gómez-Vicente, Blanca Talavera, Pere Cardona Portela, Ana Nuñez Guillen, Xabier Urra, Laura Llull, Arturo Renú, Thanh N. Nguyen…

    Citation: BMC Neurology 2021 21:43

    Content type: Research article

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  8. Immunoglobulin G4-related disease (IgG4-RD) is an immune-mediated fibro-inflammatory condition characterized by high serum IgG4 concentrations and tissue infiltration by IgG4-positive plasma cells. Reports hav...

    Authors: Jeong Bin Bong, Dong Kun Lee, Min A Lee, Byoung Wook Hwang and Hyun Goo Kang

    Citation: BMC Neurology 2021 21:41

    Content type: Case report

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  9. Surgery is a potential trigger of Guillain-Barré syndrome (GBS), a disorder which leads to an autoimmune-mediated attack of peripheral nerves. The present study was designed to explore clinical features of pos...

    Authors: Qiaoyu Gong, Shuping Liu, Yin Liu, Jiajia Yao, Xiujuan Fu, Zheman Xiao and Zuneng Lu

    Citation: BMC Neurology 2021 21:40

    Content type: Research article

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  10. Ramsay Hunt syndrome (RHS) is caused by a reactivation of varicella-zoster virus (VZV) infection, and it is characterized by the symptoms of facial paralysis, otalgia, auricular rash, and/or an oral lesion. El...

    Authors: Yuan-Mei Liao, Hai-Feng Lu, Peng Xie, Ying Zhao, Qiu Han, Qian-Xi Zhang, Xiao-Hua Zuo, Yan-Na Si and Hong-Guang Bao

    Citation: BMC Neurology 2021 21:39

    Content type: Case report

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  11. Ambulatory and balance functions are important for maintaining general health in humans. Gait analysis allows clinicians and researchers to identify the parameters to be focused on when assessing balance and a...

    Authors: Min Cheol Chang, Byung Joo Lee, Na-Young Joo and Donghwi Park

    Citation: BMC Neurology 2021 21:38

    Content type: Research article

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  12. Hemorrhagic transformation (HT) is a serious neurological complication of acute ischemic stroke (AIS) after revascularization. The majority of AIS patients do not have atrial fibrillation (AF) which could also...

    Authors: Hao-Ran Cheng, Yun-Bin Chen, Ya-Ying Zeng, Yi-Ting Ruan, Cheng-Xiang Yuan, Qian-Qian Cheng, Hui-Jun Chen, Xiao-Qian Luan, Gui-Qian Huang and Jin-Cai He

    Citation: BMC Neurology 2021 21:36

    Content type: Research article

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  13. Early stage neuromyelitis optica spectrum disorders (NMOSD) with non-opticospinal manifestations as initial symptoms are easily misdiagnosed; however, data on the full symptom profile are limited. Moreover, th...

    Authors: Rui Li, Danli Lu, Hao Li, Yuge Wang, Yaqing Shu, Yanyu Chang, Xiaobo Sun, Zhengqi Lu, Wei Qiu and Zhi Yang

    Citation: BMC Neurology 2021 21:35

    Content type: Research article

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  14. The communication of a life-changing diagnosis can be a difficult task for doctors with potential long-term effects on patient outcomes. Although several studies have addressed the experiences of individuals w...

    Authors: Eleftherios Anestis, Fiona J. R. Eccles, Ian Fletcher and Jane Simpson

    Citation: BMC Neurology 2021 21:34

    Content type: Research article

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  15. Internal carotid artery (ICA) stenosis has been recently reported to cause hemichorea, mainly in East Asia. The East Asian-specific p.R4810K variant of RNF213, a susceptibility gene for moyamoya disease (MMD), ac...

    Authors: Satoshi Hosoki, Takeshi Yoshimoto and Masafumi Ihara

    Citation: BMC Neurology 2021 21:32

    Content type: Case report

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  16. Hypothyroidism (HT) and carotid artery stenosis (CAS) are complications of radiotherapy (RT) in patients with head and neck cancer (HNC). The impact of post-RT HT on CAS progression remains unclear.

    Authors: Chi-Hung Liu, Joseph Tung-Chieh Chang, Tsong-Hai Lee, Pi-Yueh Chang, Chien-Hung Chang, Hsiu-Chuan Wu, Ting-Yu Chang, Kuo-Lun Huang, Chien-Yu Lin, Kang-Hsing Fan and Yeu-Jhy Chang

    Citation: BMC Neurology 2021 21:30

    Content type: Research article

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  17. Symplastic hemangioma is a benign superficial abnormal buildup of blood vessels, with morphological features which can mimic a pseudo malignancy. A few cases have been reported in the literature. We report her...

    Authors: Najwa Abdalkabeer A. Bantan, Ahmed H. Abouissa, Muhammad Saeed, Mustafa Hassan Alwalily, Kamal Bakour Balkhoyour, Khalid Mohammad Ashour, Amal Ali Hassan, Afnan Hisham Falemban and Mohiuddin M. Taher

    Citation: BMC Neurology 2021 21:29

    Content type: Case report

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  18. Abnormal eye movements are common in spinocerebellar ataxias Type 3 (SCA3). We conducted the research to explore the frequency of abnormal eye movements in Chinese patients with SCA3, to compare the demographi...

    Authors: Junyu Lin, Lingyu Zhang, Bei Cao, Qianqian Wei, Ruwei Ou, Yanbing Hou, Xinran Xu, Kuncheng Liu, Xiaojing Gu and Huifang Shang

    Citation: BMC Neurology 2021 21:28

    Content type: Research article

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  19. This observational study was performed to show the impact of complications and interventions during neurocritical care on the outcome after aneurysmal subarachnoid hemorrhage (SAH).

    Authors: Alexander Hammer, Frank Erbguth, Matthias Hohenhaus, Christian M. Hammer, Hannes Lücking, Markus Gesslein, Monika Killer-Oberpfalzer, Hans-Herbert Steiner and Hendrik Janssen

    Citation: BMC Neurology 2021 21:27

    Content type: Research article

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  20. To investigate the feasibility of intracranial pressure (ICP) monitoring after traumatic brain injury (TBI) by electromagnetic coupling phase sensing, we established a portable electromagnetic coupling phase s...

    Authors: Gen Li, Wang Li, Jingbo Chen, Shuanglin Zhao, Zelin Bai, Qi Liu, Qi Liao, Minglian He, Wei Zhuang, Mingsheng Chen, Jian Sun and Yujie Chen

    Citation: BMC Neurology 2021 21:26

    Content type: Research article

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  21. Meningiomas are the most common benign intracranial tumors, and commonly comprise high-vascularizing but slow-growing tumors. On the other hand, meningiomas arising from the ventricular system are of rare occu...

    Authors: Koichiro Sumi, Takeshi Suma, Reona Yoshida, Ryuta Kajimoto, Masato Kobayashi, Takamichi Katsuhara, Koki Hirayama, Xiaoyan Tang, Naoki Otani and Atsuo Yoshino

    Citation: BMC Neurology 2021 21:25

    Content type: Case report

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  22. Stroke is a major health problem around the world. Several studies have examine the influence of ambient temperature on incidence of stoke, but they reported different results for different types of stroke and...

    Authors: Mirjam Ravljen, Fajko Bajrović and Damjan Vavpotič

    Citation: BMC Neurology 2021 21:23

    Content type: Research article

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  23. Increasing evidences have showed that neuroimaging markers of SVD can predict the short-term outcome of acute ischemic stroke (AIS). It is unclear that whether neuroimaging markers of SVD are also associated w...

    Authors: Xuemei Chen, Lin Wang, Junying Jiang, Yuanyuan Gao, Rui Zhang, Xiaoyuan Zhao, Tingwen Shen, Qi Dai and Junrong Li

    Citation: BMC Neurology 2021 21:21

    Content type: Research article

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  24. The prevalence of carotid artery stenosis (CAS) in acute ischaemic stroke (AIS) patients is historically reported at 15–20%, but an up-to-date estimate is lacking. We hypothesise it is lower than historically ...

    Authors: Twan J van Velzen, Laurien S Kuhrij, Willeke F Westendorp, Diederik van de Beek and Paul J Nederkoorn

    Citation: BMC Neurology 2021 21:20

    Content type: Research article

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  25. Residual motor deficits of the upper limb in patients with chronic stroke are common and have a negative impact on autonomy, participation and quality of life. Music-Supported Therapy (MST) is an effective int...

    Authors: Jennifer Grau-Sánchez, Emma Segura, David Sanchez-Pinsach, Preeti Raghavan, Thomas F. Münte, Anna Marie Palumbo, Alan Turry, Esther Duarte, Teppo Särkämö, Jesus Cerquides, Josep Lluis Arcos and Antoni Rodríguez-Fornells

    Citation: BMC Neurology 2021 21:19

    Content type: Study protocol

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  26. Dorsolateral medullary infarction is a typical cerebral infarction which is characterized by Wallenberg’s syndrome. Neurotrophic keratopathy is an uncommon consequence of dorsolateral medullary infarction. At ...

    Authors: Jing Wang, Pei Liu, Zhongzhong Liu, Ye Tian, Guilian Zhang, Jun Guo, Li Li, Zhiqin Liu, Zucheng Han, Wenjuan Lin, Xuemei Lin, Qingli Lu, Yan Liu, Qiaoqiao Chang and Songdi Wu

    Citation: BMC Neurology 2021 21:18

    Content type: Study protocol

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  27. Glucocerebrosidase (GBA) heterozygous variants are the most important genetic risk factor for the development of alpha-synucleinopathies (i.e., Parkinson’s disease and Dementia with Lewy Bodies). Herein, we repor...

    Authors: Marina Picillo, Sara Scannapieco, Alessandro Iavarone, Monia Ginevrino, Enza Maria Valente and Paolo Barone

    Citation: BMC Neurology 2021 21:17

    Content type: Case report

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  28. Parkinson’s disease (PD), frequently accompanied by cognitive impairments, is associated with systemic oxidative stress and abnormal structural changes on brain images. We aimed to identify the correlation bet...

    Authors: Ta-Chih Chang, Yi-Cun Chen, Yu-Chi Huang, Wei-Che Lin and Cheng-Hsien Lu

    Citation: BMC Neurology 2021 21:16

    Content type: Research article

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  29. Vascular Parkinsonism(VaP) is defined as parkinsonism resulting from cerebral vascular disease(CVD), with presence of variable motor and non-motor signs that are corroborated by clinical, anatomic or imaging f...

    Authors: Shouzi Zhang, Yuanyuan Wang, Lixin Liu, Li Zhang, Li Ma, Haiyan Wu, Xuelin He, Mingwei Zhu, Luning Wang and Fan Mei

    Citation: BMC Neurology 2021 21:15

    Content type: Case report

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  30. Adenomyosis, a benign gynecological disease, causes cerebral infarction. Similar to Trousseau’s syndrome, it elevates cancer antigen 125 (CA125) and D-dimer levels; causes hypercoagulability; and results in ce...

    Authors: Ryo Aiura, Sadayoshi Nakayama, Hroo Yamaga, Yu Kato and Hirotake Fujishima

    Citation: BMC Neurology 2021 21:14

    Content type: Case report

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  31. Dystrophinopathies are the most common type of inherited muscular diseases. Muscle biopsy and genetic tests are effective to diagnose the disease but cost much more than primary hospitals can reach. The more a...

    Authors: Mei Yang, Yiming Zheng, Zhiying Xie, Zhaoxia Wang, Jiangxi Xiao, Jue Zhang and Yun Yuan

    Citation: BMC Neurology 2021 21:13

    Content type: Research article

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  32. SPG11 mutation-related autosomal recessive hereditary spastic paraplegia with thin corpus callosum (HSP-TCC) is the most common cause in complicated forms of HSP, usually presenting comprehensive mental retardati...

    Authors: Chuan Li, Qi Yan, Feng-ju Duan, Chao Zhao, Zhuo Zhang, Ying Du and Wei Zhang

    Citation: BMC Neurology 2021 21:12

    Content type: Research article

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  33. The status of research and scientific outputs with regards to bacterial central nervous system (CNS) infection in southeast Asia (SEA) is unknown. This study aimed to analyze and compare bacterial CNS infectio...

    Authors: Francis Gerwin U. Jalipa, Marie Charmaine C. Sy, Adrian I. Espiritu and Roland Dominic G. Jamora

    Citation: BMC Neurology 2021 21:11

    Content type: Research article

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  34. Currently, myelin oligodendrocyte glycoprotein (MOG)-IgG-associated encephalomyelitis (MOG-EM) is regarded as an independent inflammatory demyelinating disease. Magnetic resonance imaging (MRI) abnormalities o...

    Authors: Weibing Shen, Yaner Zhang, Chenguang Zhou and Yaoyao Shen

    Citation: BMC Neurology 2021 21:10

    Content type: Case report

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  35. Antiphospholipid syndrome (APS) is associated with a high incidence of thrombotic events, either arterial thrombosis or venous thrombosis. However, APS-related non-thrombotic venous stenosis is rarely reported.

    Authors: Si-ying Song, Gary Rajah, Yu-chuan Ding, Xun-ming Ji and Ran Meng

    Citation: BMC Neurology 2021 21:9

    Content type: Case report

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  36. Some epidemiologic studies have reported a sharp increase in multiple sclerosis (MS) incidence in different provinces in Iran. This report aimed to investigate more closely the increasing trend of MS incidence...

    Authors: Ali Hosseinzadeh, Behnaz Sedighi, Jamshid Kermanchi, Mohammad Heidari and Ali Akbar Haghdoost

    Citation: BMC Neurology 2021 21:7

    Content type: Research article

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  37. Unplanned readmission is one of many measures of the quality of care of pediatric patients with neurological conditions. In this multicenter study, we searched for novel risk factors of readmission of patients...

    Authors: Ryan O’Connell, William Feaster, Vera Wang, Sharief Taraman and Louis Ehwerhemuepha

    Citation: BMC Neurology 2021 21:5

    Content type: Research article

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  38. Stroke in adults aged between 18 and 64 years old is increasing significantly worldwide. Studies have reported that this group of young stroke survivors encounters enormous difficulties reintegrating into thei...

    Authors: Suzanne Hoi Shan Lo, Janita Pak Chun Chau, Kai Chow Choi, Edward Wai Ching Shum, Jonas Hon Ming Yeung and Siu Hung Li

    Citation: BMC Neurology 2021 21:3

    Content type: Study protocol

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  39. Migraine is a prevalent and disabling headache disorder that affects more than 1.04 billion individuals world-wide. It can result in reduction in quality of life, increased disability, and high socio-economic ...

    Authors: Philippe Ryvlin, Kirill Skorobogatykh, Andrea Negro, Rainel Sanchez-De La Rosa, Heike Israel-Willner, Christina Sundal, E. Anne MacGregor and Angel L. Guerrero

    Citation: BMC Neurology 2021 21:1

    Content type: Research article

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