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  1. Content type: Study protocol

    Differentiation of Parkinson’s disease (PD) from the various types of atypical parkinsonism (AP) such as multiple system atrophy (MSA), progressive supranuclear palsy (PSP), dementia with Lewy bodies (DLB), co...

    Authors: Anouke van Rumund, Marjolein B. Aerts, Rianne A. J. Esselink, Frederick J. A. Meijer, Marcel M. Verbeek and Bastiaan R. Bloem

    Citation: BMC Neurology 2018 18:69

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  2. Content type: Research article

    On-treatment magnetic resonance imaging lesions may predict long-term clinical outcomes in patients receiving interferon β-1a. This study aimed to assess the effect of active T2 and T1 gadolinium-enhancing (Gd...

    Authors: Anthony Traboulsee, David K. B. Li, Mark Cascione, Juanzhi Fang, Fernando Dangond and Aaron Miller

    Citation: BMC Neurology 2018 18:68

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  3. Content type: Research article

    The principal biomarker of neurodegeneration in multiple sclerosis (MS) is believed to be brain volume, which is associated with cognitive functions and retinal nerve fibre layer (RNFL). A cross-sectional and ...

    Authors: Jessica Frau, Giuseppe Fenu, Alessio Signori, Giancarlo Coghe, Lorena Lorefice, Maria Antonietta Barracciu, Vincenzo Sechi, Federico Cabras, Mauro Badas, Maria Giovanna Marrosu and Eleonora Cocco

    Citation: BMC Neurology 2018 18:67

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  4. Content type: Research article

    HIV is a neurotropic virus, and it can bring about neurodegeneration and may even result in cognitive impairments. The precise mechanism of HIV-associated white matter (WM) injury is unknown. The effects of mu...

    Authors: Rui-li Li, Jun Sun, Zhen-chao Tang, Jing-ji Zhang and Hong-jun Li

    Citation: BMC Neurology 2018 18:66

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  5. Content type: Research article

    Posterior cortical atrophy (PCA) is a group of clinical syndromes characterized by visuospatial and visuoperceptual impairment, with memory relatively preserved. Although PCA is pathologically almost identical...

    Authors: Jieying Li, Liyong Wu, Yi Tang, Aihong Zhou, Fen Wang, Yi Xing and Jianping Jia

    Citation: BMC Neurology 2018 18:65

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  6. Content type: Study protocol

    Motor outcomes of children with unilateral cerebral palsy are clearly documented and well understood, yet few studies describe the cognitive functioning in this population, and the associations between the two...

    Authors: Brian Hoare, Michael Ditchfield, Megan Thorley, Margaret Wallen, Jenny Bracken, Adrienne Harvey, Catherine Elliott, Iona Novak and Ali Crichton

    Citation: BMC Neurology 2018 18:63

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  7. Content type: Case report

    POEMS syndrome is a plasma cell disorder, which clinically manifests from paraneoplastic syndrome: polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes. The most comm...

    Authors: Panitha Jindahra, Charungthai Dejthevaporn, Pimjai Niparuck, Jariya Waisayarat, Piyaphon Cheecharoen, Thanatporn Threetong, Purit Petpiroon, Tharikarn Sujirakul, Anuchit Poonyathalang and Kavin Vanikieti

    Citation: BMC Neurology 2018 18:64

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  8. Content type: Case report

    Some metabolic disorders, including abnormal calcium metabolism, can develop and worsen parkinsonism. However, whether hyperparathyroidism can cause parkinsonism remains controversial.

    Authors: Yuichiro Ohya, Masato Osaki, Shota Sakai, Shunsuke Kimura, Chiharu Yasuda, Tetsuro Ago, Takanari Kitazono and Shuji Arakawa

    Citation: BMC Neurology 2018 18:62

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  9. Content type: Research article

    Epilepsy is a major complication of stroke. We aimed to establish whether there is an association between intravenous thrombolysis, intra-arterial thrombolysis and post stroke seizure (PSS) development. Improv...

    Authors: Jillian Naylor, Arthur Thevathasan, Leonid Churilov, Ruibing Guo, Yunyun Xiong, Miriam Koome, Ziyi Chen, Ziyuan Chen, Xinfeng Liu, Patrick Kwan and Bruce C. V. Campbell

    Citation: BMC Neurology 2018 18:61

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  10. Content type: Case report

    Pediatric autoimmune neuropsychiatric disorder after streptococcal infection (PANDAS) is a specific autoimmune response to group-A streptococcal infections in children and adolescents with a sudden onset of ob...

    Authors: A. H. Nave, P. Harmel, R. Buchert and L. Harms

    Citation: BMC Neurology 2018 18:60

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  11. Content type: Case report

    Granulomatosis with polyangiitis (GPA, formerly Wegener’s granulomatosis) is a multisystem vasculitis of small- to medium-sized blood vessels. Cranial involvement can result in cranial nerve palsies and, rarel...

    Authors: James E. Peters, Vivek Gupta, Ibtisam T. Saeed, Curtis Offiah and Ali S. M. Jawad

    Citation: BMC Neurology 2018 18:59

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  12. Content type: Research article

    Persistent and uncontrollable intracranial hypertension (ICH) and difficulty in reducing Cryptococcus count are severe problems in cryptococcal meningitis (CM) patients. The therapeutic effects of ventriculope...

    Authors: Jia Liu, Zhuo-lin Chen, Min Li, Chuan Chen, Huan Yi, Li Xu, Feng Tan and Fu-hua Peng

    Citation: BMC Neurology 2018 18:58

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  13. Content type: Research article

    This study aimed to i) examine the frequency of C9orf72 expansions in a cohort of patients with the behavioural variant frontotemporal dementia (bvFTD) phenocopy syndrome, ii) observe outcomes in a group of pheno...

    Authors: E. Devenney, T. Swinn, E. Mioshi, M. Hornberger, K. E. Dawson, S. Mead, J. B. Rowe and J. R. Hodges

    Citation: BMC Neurology 2018 18:56

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  14. Content type: Research article

    Endovascular techniques have proven beneficial in the treatment of aneurysmal subarachnoid hemorrhage (aSAH), but with high risk of arterial clotting, emboli and dissection. Platelet activation and alterations...

    Authors: Pauline Perez, Anne-Claire Lukaszewicz, Stephanie Lenck, Rémy Nizard, Ludovic Drouet and Didier Payen

    Citation: BMC Neurology 2018 18:57

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  15. Content type: Case report

    Creutzfeldt-Jakob disease is a rare and fatal neurodegenerative disorder that affects mammals and humans. The prevalence of this disease in the United States is 0.5 to 1 per million inhabitants. So far in Ecua...

    Authors: Germaine Eleanor Torres Herrán, Andrés Damián Ortega Herrera, Braulio Martinez Burbano, Marcos Serrano-Dueñas, María Angélica Ortiz Yepez, Raúl Alberto Barrera Madera, Luis Alfredo Masabanda Campaña, Guillermo David Baño Jiménez, Denny Maritza Santos Saltos and Edgar Patricio Correa Díaz

    Citation: BMC Neurology 2018 18:55

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    The Correction to this article has been published in BMC Neurology 2018 18:84

  16. Content type: Research article

    Caregiver burden may be either a predictor or an outcome of caregiver quality of life (QoL). Patient or caregiver factors that directly affect caregiver QoL, predictors that are simultaneously shared with care...

    Authors: Yu-Hsia Tsai, Meei-Fang Lou, Tsui-Hsia Feng, Tsung-Lan Chu, Ying-Jen Chen and Hsueh-Erh Liu

    Citation: BMC Neurology 2018 18:50

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  17. Content type: Research article

    It is usually difficult to identify stroke pathogenesis for single lenticulostriate infarction with nonstenotic middle cerebral artery (MCA). Our aim is to differentiate the two pathogeneses, non-branch athero...

    Authors: Li-Li Sun, Zhong-Hao Li, Wen-Xiong Tang, Lei Liu, Fei-Yan Chang, Xue-Bin Zhang, Wei-Jie Ye, Shuo Lu, Zun-Jing Liu and Xian-Jin Zhu

    Citation: BMC Neurology 2018 18:51

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  18. Content type: Case report

    Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disease. Common first symptoms are dementia, cerebellar ataxia, visual disturbance, and psychiatric symptoms. Seizure as the first symptom of CJD is...

    Authors: Keita Miyake, Takashi Hara, Etsuko Oshima, Kiyohiro Kawada, Hideki Ishizu, Yuko Yamauchi, Katsuya Satoh, Tetsuyuki Kitamoto, Shintaro Takenoshita, Seishi Terada and Norihito Yamada

    Citation: BMC Neurology 2018 18:54

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  19. Content type: Research article

    Neuromyelitis optica (NMO) spectrum disorder (NMOSD) is a devastating autoimmune inflammatory disorder of the central nervous system, which can result in blindness or paralysis. Currently, there is a dire need...

    Authors: Yujuan Jiao, Lei Cui, Weihe Zhang, Chunyu Zhang, Yeqiong Zhang, Xin Zhang and Jinsong Jiao

    Citation: BMC Neurology 2018 18:47

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  20. Content type: Research article

    Congenital sphingosine-1-phosphate (S1P) lyase deficiency due to biallelic mutations in SGPL1 gene has recently been described in association with primary adrenal insufficiency and steroid-resistant nephrotic syn...

    Authors: Gulin Sunter, Ece Oge Enver, Azad Akbarzade, Serap Turan, Pinar Vatansever, Dilek Ince Gunal, Goncagul Haklar, Abdullah Bereket, Kadriye Agan and Tulay Guran

    Citation: BMC Neurology 2018 18:48

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  21. Content type: Research article

    The general principles in the administration of anesthetic drugs entail not only the suppression of seizure activity but also the achievement of electroencephalography burst suppression (BS). However, previous...

    Authors: Kanitpong Phabphal, Suparat Chisurajinda, Thapanee Somboon, Kanjana Unwongse and Alan Geater

    Citation: BMC Neurology 2018 18:46

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  22. Content type: Case report

    Hepatic encephalopathy may manifest by a wide spectrum of neuropsychiatric symptoms, including cognitive impairment, seizures or extrapyramidal symptoms. The liver transplant can lead to improvement of the sig...

    Authors: Karin Gmitterová, Michal Minár, Miroslav Žigrai, Zuzana Košutzká, Alice Kušnírová and Peter Valkovič

    Citation: BMC Neurology 2018 18:44

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  23. Content type: Case report

    Vertebrobasilar dolichoectasia (VBD) is a clinical entity associated with ischemic stroke, compression of cranial nerves or brainstem, and hydrocephalus. There have been relatively few studies following the pr...

    Authors: Dao Pei Zhang, Yan Fang Peng, Qian Kun Ma, Min Zhao, Huai Liang Zhang and Suo Yin

    Citation: BMC Neurology 2018 18:45

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  24. Content type: Research article

    The objective of this study was to compare the changes in the electroencephalogram (EEG) in response to noxious stimuli with tail flick and hot plate responses of rats administered opiorphin.

    Authors: Preet Singh, Kavitha Kongara, David Harding, Neil Ward, Venkata Sayoji Rao Dukkipati, Craig Johnson and Paul Chambers

    Citation: BMC Neurology 2018 18:43

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  25. Content type: Case report

    Idiopathic basal ganglia calcification (IBGC) is a rare neurodegenerative disorder characterized by symmetric intracranial calcium deposition. We report a patient with IBGC associated with cerebral infarction ...

    Authors: Takuma Nishimoto, Fumiaki Oka, Hideyuki Ishihara, Mizuya Shinoyama and Michiyasu Suzuki

    Citation: BMC Neurology 2018 18:42

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  26. Content type: Research article

    Data on autonomic nervous system (ANS) activations in migraine patients are quite controversial, with previous studies reporting over- and underactivation of the sympathetic as well as parasympathetic nervous ...

    Authors: Ozan E. Eren, Ruth Ruscheweyh, Christoph Schankin, Florian Schöberl and Andreas Straube

    Citation: BMC Neurology 2018 18:41

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  27. Content type: Study protocol

    Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes mellitus with significant clinical sequelae that can affect a patient’s quality of life. Metabolic and microvascular factors are...

    Authors: Gesa Meyer-Hamme, Thomas Friedemann, Henry Johannes Greten, Rosemarie Plaetke, Christian Gerloff and Sven Schroeder

    Citation: BMC Neurology 2018 18:40

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  28. Content type: Study protocol

    Stroke survivors are more physically inactive than even the most sedentary older adults, and low activity is associated with increased risk of recurrent stroke, medical complications, and mortality. We hypothe...

    Authors: Henry Wright, Tamara Wright, Ryan T. Pohlig, Scott E. Kasner, Jonathan Raser-Schramm and Darcy Reisman

    Citation: BMC Neurology 2018 18:39

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  29. Content type: Research article

    Behavioral assessment has been acted as the gold standard for the diagnosis of disorders of consciousness (DOC) patients. The item “Functional Object Use” in the motor function sub-scale in the Coma Recovery S...

    Authors: Yuxiao Sun, Jianan Wang, Lizette Heine, Wangshan Huang, Jing Wang, Nantu Hu, Xiaohua Hu, Xiaohui Fang, Supeng Huang, Steven Laureys and Haibo Di

    Citation: BMC Neurology 2018 18:38

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  30. Content type: Case report

    The development of progressive multifocal leukoencephalopathy (PML) is associated with severe cellular immunosuppression. Good’s syndrome (GS) is a rare immunodeficiency syndrome related to thymoma, with the d...

    Authors: Tatsuya Ueno, Nobuyuki Sato, Tomoya Kon, Rie Haga, Jin-ichi Nunomura, Kazuo Nakamichi, Masayuki Saijo and Masahiko Tomiyama

    Citation: BMC Neurology 2018 18:37

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  31. Content type: Case report

    Transient global amnesia is reported to be caused by cerebral venous congestion. Internal jugular venous flow reversal in particular with the Valsalva maneuver leads to cerebral venous congestion. In addition,...

    Authors: Yuta Maetani, Masahiro Nakamori, Tomoaki Watanabe, Hayato Matsushima, Eiji Imamura and Shinichi Wakabayashi

    Citation: BMC Neurology 2018 18:36

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  32. Content type: Research article

    Amyotrophic lateral sclerosis (ALS) is a devastating motor neuron disease characterized by substantial clinical and genetic heterogeneity. Thus far, only a few TARDBP-ALS families have been reported in China, and...

    Authors: Guo-rong Xu, Wei Hu, Ling-Ling Zhan, Chong Wang, Liu-Qing Xu, Min-Ting Lin, Wan-Jin Chen, Ning Wang and Qi-Jie Zhang

    Citation: BMC Neurology 2018 18:35

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  33. Content type: Research article

    Wilson disease is a rare genetic disorder in which impaired copper excretion results in toxic copper levels and tissue damage. Manifestations are primarily hepatic and/or neuropsychiatric, with a variety of ne...

    Authors: Anna Członkowska, Tomasz Litwin, Karolina Dzieżyc, Michal Karliński, Johan Bring and Carl Bjartmar

    Citation: BMC Neurology 2018 18:34

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  34. Content type: Research article

    Intravenous tissue plasminogen activator (IV tPA) after acute ischemic stroke carries the risk of symptomatic intracerebral hemorrhage (sICH). Cerebral microbleeds (CMBs) may indicate increased risk of hemorrh...

    Authors: Martin A. Chacon-Portillo, Rafael H. Llinas and Elisabeth B. Marsh

    Citation: BMC Neurology 2018 18:33

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  35. Content type: Research article

    There have been found apoptotic changes in brain tissue samples from humans after cerebral ischemia. Caspase-cleaved cytokeratin (CCCK)-18 could appears in blood during apoptosis. High circulating levels of CC...

    Authors: Leonardo Lorente, María M. Martín, Antonia Pérez-Cejas, Luis Ramos, Mónica Argueso, Jordi Solé-Violán, Juan J. Cáceres, Alejandro Jiménez and Victor García-Marín

    Citation: BMC Neurology 2018 18:32

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  36. Content type: Study protocol

    Intracerebral hemorrhage is a devastating disease with no specific treatment modalities. A significant proportion of patients with intracerebral hemorrhage are transferred to large stroke treatment centers, su...

    Authors: Farhaan S. Vahidy, Ellie G. Meyer, Arvind B. Bambhroliya, Jennifer R. Meeks, Charles E. Begley, Tzu-Ching Wu, Jon E. Tyson, Charles C. Miller, Ritvij Bowry, Wamda O. Ahmed, Gretchel A. Gealogo, Louise D. McCullough, Steven Warach and Sean I. Savitz

    Citation: BMC Neurology 2018 18:31

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  37. Content type: Research article

    Constipation is one of the most frequent non-motor symptoms (NMS) in Parkinson’s disease (PD) and the prevalence of constipation in PD patients varies among different studies. We designed this study to survey ...

    Authors: Jing Gan, Ying Wan, Junjie Shi, Mingzhu Zhou, Zhiyin Lou and Zhenguo Liu

    Citation: BMC Neurology 2018 18:29

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  38. Content type: Research article

    A significant proportion of patients with mild ischemic stroke become disabled despite receiving intravenous thrombolytic therapy. The purpose of this study was to assess the clinical and radiological factors ...

    Authors: Dae-Hyun Kim, Deok-Soo Lee, Hyun-Wook Nah and Jae-Kwan Cha

    Citation: BMC Neurology 2018 18:30

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  39. Content type: Research article

    Pediatric-onset multiple sclerosis (POMS) prevalence and incidence rates are increasing globally. No disease-modifying therapy are approved for MS pediatric population. Hence, we aim to review the literature o...

    Authors: Raed Alroughani and Alexey Boyko

    Citation: BMC Neurology 2018 18:27

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  40. Content type: Research article

    Prognostic models have been increasingly developed to predict complete recovery in ischemic stroke. However, questions arise about the performance characteristics of these models. The aim of this study was to ...

    Authors: Nampet Jampathong, Malinee Laopaiboon, Siwanon Rattanakanokchai and Porjai Pattanittum

    Citation: BMC Neurology 2018 18:26

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  41. Content type: Research article

    The aim of this study was to evaluate whether the glutathione S-transferase M1 (GSTM1) and T1 (GSTT1) null alleles may contribute to carbamazepine-induced hepatotoxicity.

    Authors: Chahra Chbili, Anis Hassine, Neila Fathallah, Manel Nouira, Salma Naija, Sofiene Ben Ammou and Saad Saguem

    Citation: BMC Neurology 2018 18:24

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  42. Content type: Research article

    Spiral drawing on papers is a common tremor evaluation tool for diagnosing patients with essential tremor (ET) or Parkinson’s disease (PD). No standard drawing methods and parameters that use graphic tablets a...

    Authors: Po-Chieh Lin, Kai-Hsiang Chen, Bing-Shiang Yang and Yu-Jung Chen

    Citation: BMC Neurology 2018 18:25

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  43. Content type: Research article

    Nosocomial infection (NI) control is an important issue in neurocritical care due to secondary brain damage and the increased morbidity and mortality of primary acute neurocritical care patients. The primary a...

    Authors: Vera Spatenkova, Ondrej Bradac, Daniela Fackova, Zdenka Bohunova and Petr Suchomel

    Citation: BMC Neurology 2018 18:23

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  44. Content type: Research article

    The objective of this study was to evaluate and identify the risk factors for developing a new or enlarged intracranial hemorrhage (ICH) after the placement of an external ventricular drain.

    Authors: A. Shaun Rowe, Derrick R. Rinehart, Stephanie Lezatte and J. Russell Langdon

    Citation: BMC Neurology 2018 18:22

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  45. Content type: Research article

    Chronic kidney disease increases stroke incidence and severity but the mechanisms behind this cerebro-renal interaction are mostly unexplored. Since both vascular beds share similar features, microvascular dys...

    Authors: Pedro Castro, Elsa Azevedo, Isabel Rocha, Farzaneh Sorond and Jorge M. Serrador

    Citation: BMC Neurology 2018 18:21

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