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  1. In recent years, alkaline phosphatase (ALP) has been considered as one of the independent risk factors of acute ischemic stroke (AIS) and leads to worse clinical outcomes in patients with renal failure. In thi...

    Authors: Zhongzhong Liu, Xuemei Lin, Lingxia Zeng, Qingli Lu, Pei Liu, Jing Wang, Yan Liu, Qiaoqiao Chang, Yan Wang, Chensheng Song, Fang Wang, Yaling Shi, Guozheng Liu, Qing Wang and Songdi Wu
    Citation: BMC Neurology 2022 22:249
  2. Cryptococcal meningoencephalitis (CM) is a severe infection of central nervous system with high mortality and morbidity. Infection-related inflammatory syndrome is a rare complication of CM. Herein, we report ...

    Authors: Xiao-Hong Su, Wei-Peng Li, Qi Lin, Xiu-Jun Zheng, Ting Fang, Ying Jiang and Fu-Hua Peng
    Citation: BMC Neurology 2022 22:247
  3. Children with cerebral palsy (CP) often have communication impairments, including speech altered intelligibility. Multiple levels of disrupted speech have been reported in CP, which negatively impact on partic...

    Authors: S. Fiori, C. Ragoni, I. Podda, A. Chilosi, C. Amador, P. Cipriani, A. Guzzetta and G. Sgandurra
    Citation: BMC Neurology 2022 22:246
  4. Patient involvement in discharge planning of patients with stroke can be accomplished by providing personalized outcome information and promoting shared decision-making. The aim of this study was to develop a ...

    Authors: J. C. M. Prick, S. M. van Schaik, I. A. Deijle, R. Dahmen, P. J. A. M. Brouwers, P. H. E. Hilkens, M. M. Garvelink, N. Engels, J. W. Ankersmid, S. H. J. Keus, R. The, A. Takahashi, C. F. van Uden-Kraan, P. J. van der Wees and R. M. Van den Berg-Vos
    Citation: BMC Neurology 2022 22:245
  5. Oculopharyngodistal myopathy (OPDM) is an adult-onset neuromuscular disease characterized by progressive ocular, facial, pharyngeal, and distal limb muscle involvement. Recent research showed that GGC repeat e...

    Authors: Guang Ji, Yuan Zhao, Jian Zhang, Hui Dong, Hongran Wu, Xian Chen, Xiaoming Qi, Yun Tian, Lu Shen, Guofeng Yang and Xueqin Song
    Citation: BMC Neurology 2022 22:243

    The Correction to this article has been published in BMC Neurology 2022 22:295

  6. Anti-dipeptidyl-peptidase-like protein 6 (DPPX) encephalitis is a rare autoimmune encephalitis. The clinical symptoms of anti-DPPX encephalitis are often severe, manifested as diarrhea/weight loss, central ner...

    Authors: Jing Lin, Min Zhu, Xiaocheng Mao, Zeqing Jin, Meihong Zhou and Daojun Hong
    Citation: BMC Neurology 2022 22:242
  7. Allogeneic hematopoietic stem cell transplantation is a potentially curative treatment for acute myeloid leukemia. However, extramedullary relapse of acute myeloid leukemia can occur after hematopoietic stem c...

    Authors: Shogo Shirota, Daisuke Katoh, Yoshimitsu Shimomura, Yukihiro Imai and Takayuki Ishikawa
    Citation: BMC Neurology 2022 22:241
  8. Gait disturbances may appear prior to cognitive dysfunction in the early stage of silent cerebrovascular disease (SCD). Subtle changes in gait characteristics may provide an early warning of later cognitive de...

    Authors: Yan-min Tang, Bei-ni Fei, Xin Li, Jin Zhao, Wei Zhang, Guo-you Qin, Min Hu, Jing Ding and Xin Wang
    Citation: BMC Neurology 2022 22:240
  9. Patients with poor-grade aneurysmal subarachnoid hemorrhage (aSAH) often receive delayed or no aneurysm treatment, although recent studies suggest that functional outcome following early aneurysm treatment has...

    Authors: Jordi de Winkel, Tim Y. Cras, Ruben Dammers, Pieter-Jan van Doormaal, Mathieu van der Jagt, Diederik W. J. Dippel, Hester F. Lingsma and Bob Roozenbeek
    Citation: BMC Neurology 2022 22:239
  10. Stroke is one of the most frequent diseases, and half of the stroke survivors are left with permanent impairment. Prediction of individual outcome is still difficult. Many but not all patients with stroke impr...

    Authors: Corinna Blum, David Baur, Lars-Christian Achauer, Philipp Berens, Stephanie Biergans, Michael Erb, Volker Hömberg, Ziwei Huang, Oliver Kohlbacher, Joachim Liepert, Tobias Lindig, Gabriele Lohmann, Jakob H. Macke, Jörg Römhild, Christine Rösinger-Hein, Brigitte Zrenner…
    Citation: BMC Neurology 2022 22:238
  11. Intraplaque hemorrhage (IPH) is a hallmark of carotid plaque vulnerability. We aim to investigate the association between IPH and recurrent ipsilateral ischemic stroke.

    Authors: Fengli Che, Donghua Mi, Anxin Wang, Yi Ju, Binbin Sui, Xiaokun Geng, Xihai Zhao and Xingquan Zhao
    Citation: BMC Neurology 2022 22:237
  12. Stress hyperglycemia is a common condition in patients suffering from critical illness such as spontaneous intracerebral hemorrhage (ICH). Our study aimed to use glucose-to-glycated hemoglobin (HbA1c) ratio to...

    Authors: Sijia Li, Yu Wang, Wenjuan Wang, Qian Zhang, Anxin Wang and Xingquan Zhao
    Citation: BMC Neurology 2022 22:236
  13. Many patients with neurological disorders experience chronic fatigue, but the neural mechanisms involved are unclear.

    Authors: Ying Zhang, Hong-xi Chen, Zi-yan Shi, Qin Du, Jian-cheng Wang, Xiao-fei Wang, Yu-han Qiu, Yan-lin Lang, Ling-yao Kong, Lin-jun Cai, Xue Lin, Zi-chao Mou, Wen-qin Luo, Shuang-jie Li and Hong-yu Zhou
    Citation: BMC Neurology 2022 22:235
  14. Delirium, a common complication after stroke, is often overlooked, and long-term consequences are poorly understood. This study aims to explore whether delirium in the acute phase of stroke predicts cognitive ...

    Authors: Vilde Nerdal, Elise Gjestad, Ingvild Saltvedt, Ragnhild Munthe-Kaas, Hege Ihle-Hansen, Truls Ryum, Stian Lydersen and Ramune Grambaite
    Citation: BMC Neurology 2022 22:234
  15. The present case contributes to the limited literature on central nervous system involvement of blastic plasmacytoid dendritic cell neoplasm (BPDCN). 

    Authors: Anna Maria Florescu, Anne Louise Tølbøll Sørensen, Henrik Vedel Nielsen, Daniel Tolnai, Lene Dissing Sjö, Katja Lohmann Larsen and Mohammad Al-Mahdi Al-Karagholi
    Citation: BMC Neurology 2022 22:233
  16. Insulin has been demonstrated to play an important role in the occurrence and development of Alzheimer’s disease, especially in those with diabetes. β cells are important insulin-producing cells in human pancr...

    Authors: Mengyi Guo, Jiaokun Jia, Jia Zhang, Mingyue Zhou, Anxin Wang, Shengyun Chen and Xingquan Zhao
    Citation: BMC Neurology 2022 22:232
  17. Stroke is the main cause of oropharyngeal neurogenic dysphagia. Electrostimulation has been used as a therapeutic tool in these cases. However, there are few studies that prove its effectiveness. We evaluated ...

    Authors: Klayne Cunha Matos, Vanessa Fernandes de Oliveira, Paula Luanna Carvalho de Oliveira, Fabíola Aureliano Carvalho, Maria Renata Matos de Mesquita, Camila Gabriella da Silva Queiroz, Levi Mota Marques, Débora Lilian Nascimento Lima, Fernanda Martins Maia Carvalho and Pedro Braga-Neto
    Citation: BMC Neurology 2022 22:231
  18. Psychological interventions are shown to be effective in migraine, but not utilized routinely yet. We aimed to evaluate the efficacy of transdiagnostic cognitive behavioral therapy (TCBT) on people with migrai...

    Authors: Forouzandeh Soleimanian-Boroujeni, Negin Badihian, Shervin Badihian, Vahid Shaygannejad and Yousef Gorji
    Citation: BMC Neurology 2022 22:230
  19. As endovascular thrombectomy (EVT) is time-dependent, it is crucial to refer patients promptly. Current referral modes include Mothership (MS), Drip and Ship (DS) and Drive the Doctor (DD). The purpose of this...

    Authors: Jie Hou, Zhi-liang Guo, Zhi-chao Huang, Huai-shun Wang, Shou-jiang You and Guo-dong Xiao
    Citation: BMC Neurology 2022 22:228
  20. Ischemic stroke is the most common presentation of cervical artery dissection (CAD). Information regarding CAD-induced stroke is scarce, especially in the Middle East. Here we investigated the incidence of CAD...

    Authors: Mahta Ranjbar, Negin Badihian, Maryam Yazdi, Shahaboddin Milani, Marzieh Taheri, Fariborz Khorvash and Mohammad Saadatnia
    Citation: BMC Neurology 2022 22:227
  21. Patients with bone metastasis often experience severe pain that is difficult to control and seriously affects quality of life. Radiotherapy is an effective way to relieve pain in these patients. Currently, the...

    Authors: Li Yuan, Lidan Geng, Danfeng Wu, Tangzhi Dai, Gang Feng and Xiaobo Du
    Citation: BMC Neurology 2022 22:226
  22. Posterior reversible encephalopathy syndrome (PRES) is a disorder of reversible vasogenic brain oedema with acute neurologic symptoms. It is a rare but serious disease that affects the central nervous system. ...

    Authors: Bazhu, Yanhui Shi, Shuang Ren, Liang Shu and Qiang Li
    Citation: BMC Neurology 2022 22:225
  23. Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is a common type of autoimmune encephalitis. Patients with this condition are frequently very ill but are often misdiagnosed in the Emergency Depart...

    Authors: Jin Xu, Na Zhao, Hongzhi Guan, Joseph Harold Walline, Huadong Zhu and Xuezhong Yu
    Citation: BMC Neurology 2022 22:224
  24. Eccrine spiradenocarcinoma (SC), also known as malignant eccrine spiradenoma, is a rare malignant cutaneous adnexal neoplasm arising from long-standing benign eccrine spiradenoma. Malignant skin tumors rarely ...

    Authors: Yuji Kibe, Kuniaki Tanahashi, Kazuhiro Ohtakara, Yuka Okumura, Fumiharu Ohka, Kazuhito Takeuchi, Yuichi Nagata, Kazuya Motomura, Sho Akahori, Akihiro Mizuno, Hiroo Sasaki, Hiroyuki Shimizu, Junya Yamaguchi, Tomohide Nishikawa, Kenji Yokota and Ryuta Saito
    Citation: BMC Neurology 2022 22:223
  25. Systemic lupus erythematosus (SLE) is a chronic multisystem autoimmune inflammatory disease predominantly found in women of child-bearing age. Neurogenic pulmonary edema (NPE) is a recalcitrant complication th...

    Authors: Rongqi Li, Yingai Wang, Xiuhua Wu, Junping Wang, Wei Wei and Xin Li
    Citation: BMC Neurology 2022 22:222
  26. Erenumab is a fully human monoclonal antibody and a highly potent, first-in-class calcitonin gene-related peptide receptor inhibitor approved for migraine prevention in adults. Randomised, placebo-controlled t...

    Authors: Taoufik Alsaadi, Suzan Noori, Razmig Varakian, Saly Youssef and AbuBaker Almadani
    Citation: BMC Neurology 2022 22:221
  27. Upper limb (UL) paresis is one of the most common stroke consequences and significantly restricts patients in everyday life. Instruments objectively measuring direct arm use in stroke patients are lacking, but...

    Authors: Anne-Lisa Heye, Christine Kersting, Malte Kneer and Anne Barzel
    Citation: BMC Neurology 2022 22:220
  28. Amyotrophic lateral sclerosis (ALS) is an incurable and rapidly progressive neurological disorder. Biomarkers are critical to understanding disease causation, monitoring disease progression and assessing the e...

    Authors: Maize C. Cao, Erin E. Cawston, Grace Chen, Collin Brooks, Jeroen Douwes, Dave McLean, E. Scott Graham, Mike Dragunow and Emma L. Scotter
    Citation: BMC Neurology 2022 22:216
  29. Wake-up ischemic stroke (IS) has been usually excluded from acute stroke therapy options for being outside of the safe treatment window. We identified risk factors, and clinical or molecular biomarkers that co...

    Authors: Pablo Hervella, María Luz Alonso-Alonso, María Pérez-Mato, Manuel Rodríguez-Yáñez, Susana Arias-Rivas, Iria López-Dequidt, José M. Pumar, Tomás Sobrino, Francisco Campos, José Castillo and Ramón Iglesias-Rey
    Citation: BMC Neurology 2022 22:215
  30. Missense mutations in the mitochondrial alanyl-tRNA synthetase 2 (AARS2) gene are clinically associated with infantile mitochondrial cardiomyopathy or adult-onset leukoencephalopathy with early ovarian failure. T...

    Authors: Yan Fan, Jinming Han, Yanyan Yang and Tuanzhi Chen
    Citation: BMC Neurology 2022 22:214
  31. We aimed to investigate the risk factors of early neurological deterioration (END) after intravenous thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) and the relationship between END and...

    Authors: Fengli Che, Anxin Wang, Yi Ju, Yarong Ding, Honglian Duan, Xiaokun Geng, Xingquan Zhao and Yongjun Wang
    Citation: BMC Neurology 2022 22:212
  32. Over a dozen disease-modifying therapies (DMTs) have been approved for treatment of multiple sclerosis (MS). Treatment guidelines focus on when to initiate, change, and discontinue treatment but provide little...

    Authors: Robert J. Fox, Rina Mehta, Timothy Pham, Julie Park, Kathleen Wilson and Machaon Bonafede
    Citation: BMC Neurology 2022 22:211
  33. A subgroup of individuals experienced stroke-like symptoms after receiving an inactivated COVID-19 vaccine. We present clinical characteristics, neuroimaging, and outcome of these patients.

    Authors: Duangnapa Roongpiboonsopit, Chichaya Nithisathienchai, Wasan Akarathanawat, Krittanon Lertutsahakul, Jarturon Tantivattana, Anand Viswanathan and Nijasri Charnnarong Suwanwela
    Citation: BMC Neurology 2022 22:210
  34. The present strategies regarding poststent management for cerebral venous sinus stenosis (CVSS) are inconsistent. Herein, we compared the safety and efficacy of oral anticoagulants (OACs) plus single antiplate...

    Authors: Chaobo Bai, Zhiying Chen, Xiaoqin Wu, Roxanne Ilagan, Yuchuan Ding, Xunming Ji and Ran Meng
    Citation: BMC Neurology 2022 22:209
  35. So far, the diagnosis of acute artery of percheron (AOP) infarction is uncommon. In this study, patients with acute AOP infarction were studied to explore the relationship of imaging findings, clinical manifes...

    Authors: Bei Zhang, Xiaoxun Wang, Chen Gang and Jiping Wang
    Citation: BMC Neurology 2022 22:207
  36. The development of tools that could help emergency department clinicians recognize stroke during triage could reduce treatment delays and improve patient outcomes. Growing evidence suggests that stroke is asso...

    Authors: Grant C. O’Connell, Kyle B. Walsh, Christine G. Smothers, Suebsarn Ruksakulpiwat, Bethany L. Armentrout, Chris Winkelman, Truman J. Milling, Steven J. Warach and Taura L. Barr
    Citation: BMC Neurology 2022 22:206
  37. Eptinezumab is an anti-calcitonin gene-related peptide (CGRP) monoclonal antibody approved for the preventive treatment of migraine. In the phase 3 RELIEF study, eptinezumab resulted in shorter time to headach...

    Authors: Jessica Ailani, Peter McAllister, Paul K. Winner, George Chakhava, Mette Krog Josiassen, Annika Lindsten, Bjørn Sperling, Anders Ettrup and Roger Cady
    Citation: BMC Neurology 2022 22:205
  38. It is important to assess the degree of brain injury and predict long-term outcomes in neonates diagnosed with hypoxic-ischemic encephalopathy (HIE). However, routine studies, including magnetic resonance imag...

    Authors: Kwang Yeon Kim, Joo-Young Lee, Ja-Un Moon, Tae-Hoon Eom and Young-Hoon Kim
    Citation: BMC Neurology 2022 22:204
  39. To explore the expression relationship and significance of long chain non-coding RNA nuclear-enriched abundant transcript 1 (LncRNA NEAT1) and miR-27a-3p in serum and cerebrospinal fluid of patients with Alzhe...

    Authors: Lijie He, Zongnan Chen, Jing Wang and Heqiang Feng
    Citation: BMC Neurology 2022 22:203
  40. Neural tube defects (NTDs) are associated with high rates of neonatal mortality and morbidity worldwide. The promotion of folic acid fortification and supplementation in pregnant women by the Food and Drug Adm...

    Authors: Paddy Ssentongo, Emily S. Heilbrunn, Anna E. Ssentongo, Lydia V. N. Ssenyonga and Alain Lekoubou
    Citation: BMC Neurology 2022 22:202
  41. For patients with aneurysmal subarachnoid hemorrhages (SAHs) and multiple intracranial aneurysms (MIAs), a simple and fast imaging method that can identify ruptured intracranial aneurysms (RIAs) may have great...

    Authors: Xue-hua Zhang, Xiao-yan Zhao, Lan-lan Liu, Li Wen and Guang-xian Wang
    Citation: BMC Neurology 2022 22:201
  42. Hereditary spastic paraplegia 7 (SPG7) is one of the subtypes of autosomal-recessive hereditary spastic paraplegia, which is a clinically heterogeneous neurodegenerative disorder. SPG7 often displays a complic...

    Authors: Shan Wang, Yaye Wang, Yue Wu, Jinru Zhang, Weilin Zhang, Chang Li and Xueqin Song
    Citation: BMC Neurology 2022 22:200
  43. Specific dietary recommendations for migraine patients with comorbid irritable bowel syndrome (IBS) are lacking. This work aimed to study the severity scores of such two common pain-related disorders in relati...

    Authors: Rehab Magdy, Ragaey A Eid, Mahmoud Hassan, Mohamed Abdelghaffar, Asmaa F El Sayed, Zeinab Mohammed and Mona Hussein
    Citation: BMC Neurology 2022 22:199

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