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  1. Mild cognitive impairment (MCI) is an intermediate stage between normal aging and dementia. Studies on MCI progression are important for Alzheimer’s disease (AD) prevention. 18F fluoro-deoxy-glucose positron e...

    Authors: Lirong Teng, Yongchao Li, Yu Zhao, Tao Hu, Zhe Zhang, Zhijun Yao and Bin Hu

    Citation: BMC Neurology 2020 20:148

    Content type: Research article

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  2. Cerebrovascular disease (CVD) survivors are at a high risk of recurrent stroke. Although it is thought that survivors with higher risk of stroke respond better to stroke onset, to date, no study has been able ...

    Authors: Shengde Li, Li-Ying Cui, Craig Anderson, Chunpeng Gao, Chengdong Yu, Guangliang Shan, Longde Wang and Bin Peng

    Citation: BMC Neurology 2020 20:147

    Content type: Research article

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  3. Parkinson disease (PD) is a debilitating and chronic neurodegenerative disease resulting in ambulation difficulties. Natural walking activity often declines early in disease progression despite the relative st...

    Authors: Kerri S. Rawson, James T. Cavanaugh, Cristina Colon-Semenza, Tami DeAngelis, Ryan P. Duncan, Daniel Fulford, Michael P. LaValley, Pietro Mazzoni, Timothy Nordahl, Lisa M. Quintiliani, Marie Saint-Hilaire, Cathi A. Thomas, Gammon M. Earhart and Terry D. Ellis

    Citation: BMC Neurology 2020 20:146

    Content type: Study protocol

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  4. Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late onset, X-linked genetic, neurodegenerative disorder caused by a “premutation (PM)” in the fragile X mental retardation 1 (FMR1) gene. Here we report a...

    Authors: Cuiping Zhao, Yiming Liu, Yihua Wang, Hongyan Li, Bin Zhang, Yaoxian Yue and Jianyuan Zhang

    Citation: BMC Neurology 2020 20:145

    Content type: Case report

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  5. Vagal nerve stimulation (VNS) can be an effective therapy for patients with epilepsy refractory to anti-epileptic drugs or intracranial surgery. While generally well tolerated, it has been associated with lary...

    Authors: James B. Nichols, Abigail P. McCallum, Nicolas K. Khattar, George Z. Wei, Rakesh Gopinathannair, Haring J. W. Nauta and Joseph S. Neimat

    Citation: BMC Neurology 2020 20:144

    Content type: Case report

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  6. This meta-analysis was designed to investigate the long-term efficacy and safety between cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF) in treating cervical disc degenerati...

    Authors: Yijian Zhang, Nanning Lv, Fan He, Bin Pi, Hao Liu, Angela Carley Chen, Huilin Yang, Mingming Liu and Xuesong Zhu

    Citation: BMC Neurology 2020 20:143

    Content type: Research article

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  7. Hydrocephalus is a common, life threatening complication of human immunodeficiency virus (HIV)-related central nervous system opportunistic infection which can be treated by insertion of a ventriculoperitoneal...

    Authors: James J. M. Loan, Michael T. C. Poon, Steven Tominey, Ncedile Mankahla, Graeme Meintjes and A. Graham Fieggen

    Citation: BMC Neurology 2020 20:141

    Content type: Research article

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  8. Presently, for patients presenting with suspected Normal Pressure Hydrocephalus (NPH) who undergo temporary drainage of cerebrospinal fluid (CSF) there is no defined model to differentiate chance improvement f...

    Authors: Alexander Davis, Sevil Yasar, Iris Emerman, Seema Gulyani, Kristina Khingelova, Aruna Rao, Lacie Manthripragada, Mark Luciano and Abhay Moghekar

    Citation: BMC Neurology 2020 20:140

    Content type: Research article

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  9. Endovascular therapy is widely used in acute large vessel occlusion. This study investigated whether imaging of lateral lenticulostriate arteries (LSAs) before thrombectomy would potentially be helpful for pre...

    Authors: Feifeng Liu, Chen Chen, Lan Hong, Hao Shen, Wenjie Cao, Qiang Dong, Xinyi Yang, Mengruo Guo, Ying Li, Yaping Xiao, Xin Cheng and Gang Li

    Citation: BMC Neurology 2020 20:139

    Content type: Research article

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  10. Fragile X syndrome (FXS) is the most frequent cause of inherited intellectual disability and the most commonly identified monogenic cause of autism. Recent studies have shown that long-term pathological conseq...

    Authors: Anke Van Dijck, Susana Barbosa, Patricia Bermudez-Martin, Olfa Khalfallah, Cyprien Gilet, Emanuela Martinuzzi, Ellen Elinck, R. Frank Kooy, Nicolas Glaichenhaus and Laetitia Davidovic

    Citation: BMC Neurology 2020 20:138

    Content type: Research article

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  11. Executive control dysfunction is observed in a sizable number of patients with temporal lobe epilepsy (TLE). Neural oscillations in the theta band are increasingly recognized as having a crucial role in execut...

    Authors: Yanping Ren, Liping Pan, Xueyun Du, Yuying Hou, Xun Li and Yijun Song

    Citation: BMC Neurology 2020 20:137

    Content type: Research article

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  12. Following acute ischemic stroke (AIS), approximately half of patients do not achieve recanalization after intravenous administration of tissue plasminogen activator (rt-PA). Thrombolysis resistance is a possib...

    Authors: Ye Li, Heying Wang, Lili Zhao, Yating Jian, Meijuan Dang, Yu Jiang, Yiheng Zhang, Lei Zhang, Huqing Wang, Ru Zhang, Mingxia Chen and Guilian Zhang

    Citation: BMC Neurology 2020 20:135

    Content type: Case report

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  13. For acute ischemic stroke (AIS) patient receiving mechanical thrombectomy (MT), renal dysfunction was an independent risk factor of contrast-induced nephropathy which may affect clinical outcomes. However, the...

    Authors: Xiding Pan, Feng Zhou, Rui Shen, Yubing Zhu, Hisatomi Arima, Jie Yang and Junshan Zhou

    Citation: BMC Neurology 2020 20:134

    Content type: Research article

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  14. Cerebral palsy (CP) causes motor, cognitive and sensory impairment at different extents. Many recent rehabilitation developments (therapies) have focused solely on the upper extremities (UE), although the lowe...

    Authors: R. Araneda, S. V. Sizonenko, C. J. Newman, M. Dinomais, G. Le Gal, E. Nowak, A. Guzzetta, I. Riquelme, S. Brochard and Y. Bleyenheuft

    Citation: BMC Neurology 2020 20:133

    Content type: Study protocol

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  15. RLS is known as one of the most common movement disorders during pregnancy, which is most aggravated in the third trimester of pregnancy and can affect up to one-third of pregnant women. This study intends to ...

    Authors: Niloofar Darvishi, Alireza Daneshkhah, Behnam Khaledi-Paveh, Aliakbar Vaisi-Raygani, Masoud Mohammadi, Nader Salari, Fateme Darvishi, Alireza Abdi and Rostam Jalali

    Citation: BMC Neurology 2020 20:132

    Content type: Research article

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  16. Cavernous malformations are rare cerebral pseudo-vascular lesions with annualized bleeding rates of 0.5–3% in most studies. Of the various explored risk factors for bleeding to date, only prior hemorrhage has ...

    Authors: Benjamin R. Hartley, Corinne Birnbaum and Caitlin E. Hoffman

    Citation: BMC Neurology 2020 20:131

    Content type: Case report

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  17. We imaged the corticospinal tract (CST) and corticoreticular pathway (CRP) using diffusion tensor tractography (DTT) to evaluate the cause of muscle weakness in a patient who was exposed to high-voltage electr...

    Authors: Mathieu Boudier-Revéret, Ming-Yen Hsiao, Shaw-Gang Shyu and Min Cheol Chang

    Citation: BMC Neurology 2020 20:130

    Content type: Case report

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  18. Hyperhomocysteinemia (HHCY) is a risk factor for cardiovascular and cerebrovascular diseases. The C677T 5, 10-methylenetetrahydrofolate reductase (MTHFR) gene polymorphism increases homocysteine (HCY) levels. ...

    Authors: Xiaoxia Du, Lin Xiao, Rong Sun, Kunpeng Li, Lin Liang, Luping Song and Zhizhong Liu

    Citation: BMC Neurology 2020 20:128

    Content type: Research article

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  19. The modified Rankin Scale (mRS) is a key global outcome measure after stroke internationally. The latest English version of the simplified modified Rankin scale questionnaire (smRSq)(2011) is a reliable and va...

    Authors: Junliang Yuan, Yunxiao Wang, Wenli Hu and Askiel Bruno

    Citation: BMC Neurology 2020 20:127

    Content type: Research article

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  20. IncobotulinumtoxinA (Xeomin®) is a botulinum neurotoxin type A with established efficacy in the treatment of upper-limb spasticity in adults. This retrospective case series in a university hospital setting aim...

    Authors: Angel León-Valenzuela, Juan Sánchez Palacios and Rogelio del Pino Algarrada

    Citation: BMC Neurology 2020 20:126

    Content type: Research article

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  21. Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative condition characterized by the loss of neurons and the presence of eosinophilic nuclear inclusions in the central and peripheral nervo...

    Authors: Mingming Li, Kai Li, Xin Li, Yun Tian, Lu Shen, Guode Wu, Zaiqiang Zhang and Weian Chen

    Citation: BMC Neurology 2020 20:125

    Content type: Case report

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  22. A new type of epileptogenic tumor, the polymorphous low-grade neuroepithelial tumor of the young (PLNTY) was firstly reported by Jason T. Huse et al. at 2016. After that, only 1 case of PLNTY was reported by a...

    Authors: Yingqian Chen, Tian Tian, Xinwen Guo, Fenfen Zhang, Miao Fan, Huawei Jin and Dawei Liu

    Citation: BMC Neurology 2020 20:123

    Content type: Case report

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  23. Reversible splenial lesion syndrome (RESLES) is known to cause severe psychiatric symptoms but is also a very rare clinical disease in which the specific aetiology is unknown. According to current reports, the...

    Authors: Song Hu, Xinyue Hou, Shuhao Liu, Chunxiao Fei, Lingyan Zhou, Ang Xing, Junqing Zhang, Chunming Yong and Xiaomeng Wang

    Citation: BMC Neurology 2020 20:122

    Content type: Case report

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  24. Spinal dysraphism with a hamartomatous growth (appendix) of the spinal cord is better known as herniated spinal cord. There are many arguments in favour of considering it a developmental defect. From this poin...

    Authors: Ronald H. M. A. Bartels, J. Andre Grotenhuis, Alexander P. A. Stegmann and Han Brunner

    Citation: BMC Neurology 2020 20:121

    Content type: Case report

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  25. This systematic review and meta-analysis aimed to synthesize the latest evidence on the efficacy and safety of tranexamic acid (TXA) on traumatic brain injury (TBI).

    Authors: Julius July and Raymond Pranata

    Citation: BMC Neurology 2020 20:119

    Content type: Research article

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  26. Acute hyperammonemia without signs of common causes in the elderly might be challenging to identify. We report the oldest case known to date of a female patient with late onset ornithine carbamyltransferase de...

    Authors: Justus Marquetand, Peter Freisinger, Tobias Lindig, Sebastian Euler, Michael Gasser and Dietrich Overkamp

    Citation: BMC Neurology 2020 20:118

    Content type: Case report

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  27. Associations between serum phosphorus level and the incidence of ischemic stroke are not clear. This study aimed to measure serum phosphorus, vitamin D3, and uric acid levels in ischemic stroke patients compar...

    Authors: Abolfazl Talebi, Alireza Amirabadizadeh, Samaneh Nakhaee, Zahra Ahmadi and Seyed Mohammad Mousavi-Mirzaei

    Citation: BMC Neurology 2020 20:116

    Content type: Research article

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  28. Cytokines are possible mediators of neuroinflammation and associated with adverse outcome in neonatal encephalopathy (NE). Our aim was to explore cytokine response in children with Neonatal Encephalopathy (NE)...

    Authors: Zunera Zareen, Tammy Strickland, Victoria Mc Eneaney, Lynne A. Kelly, Denise McDonald, Deirdre Sweetman and Eleanor J. Molloy

    Citation: BMC Neurology 2020 20:115

    Content type: Research article

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  29. Progressive supranuclear palsy (PSP) is a rare movement disorder with poor prognosis. This retrospective study aimed to characterize the natural history of PSP and to find predictors of shorter survival and fa...

    Authors: Shi-Shuang Cui, Hua-Wei Ling, Juan-Juan Du, Yi-Qi Lin, Jing Pan, Hai-Yan Zhou, Gang Wang, Ying Wang, Qin Xiao, Jun Liu, Yu-Yan Tan and Sheng-Di Chen

    Citation: BMC Neurology 2020 20:114

    Content type: Research article

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  30. Detection of brain-MRI T2/T2* gradient echo images (T2*GRE)-hypointensity can be compatible with iron accumulation and leads to a differential diagnosis work-up including neurodegeneration with brain iron accu...

    Authors: Stefania Scarlini, Francesco Cavallieri, Massimo Fiorini, Elisa Menozzi, Francesca Ferrara, Francesca Cavalleri, Chiara Reale, Barbara Garavaglia, Antonello Pietrangelo, Franco Valzania and Elena Corradini

    Citation: BMC Neurology 2020 20:113

    Content type: Case report

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  31. Patients with Alzheimer’s disease dementia (ADD) are thought to exhibit taste disorders; however, this has not been extensively studied. We investigated gustatory functions and factors affecting taste in patie...

    Authors: Minoru Kouzuki, Junya Ichikawa, Daiki Shirasagi, Fumiya Katsube, Yuuki Kobashi, Hideki Matsumoto, Huichia Chao, Shintaro Yoshida and Katsuya Urakami

    Citation: BMC Neurology 2020 20:110

    Content type: Research article

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  32. French Guiana has the highest incidence of ischemic and hemorrhagic stroke of all French territories. However, there is no further information on the epidemiology and management of stroke in French Guiana. Our...

    Authors: Dévi Rita Rochemont, Emmanuelle Mimeau, Caroline Misslin-Tritsch, Martine Papaix-Puech, Emmanuel Delmas, Yannick Bejot, Bertrand DeToffol, Isabelle Fournel and Mathieu Nacher

    Citation: BMC Neurology 2020 20:109

    Content type: Research article

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  33. Bilateral medial medullary infarction (MMI) is uncommon and bilateral medial pons infarction (MPI) is even rarer. “Heart appearance” on magnetic resonance imaging (MRI) is a characteristic presentation of bila...

    Authors: Zhi-Hua Zhou, Yun-Fan Wu, Wei-Feng Wu, Ai-Qun Liu, Qing-Yun Yu, Zhong-Xing Peng and Ming-Fan Hong

    Citation: BMC Neurology 2020 20:107

    Content type: Case report

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  34. Psoriasis is the most common chronic inflammatory condition involving the T helper cell system. Population studies have demonstrated that patients with psoriasis and/or psoriatic arthritis have an increased ri...

    Authors: Joline M. Fan, David A. Solomon, Giselle Y. López, Jeffrey W. Hofmann, Rene A. Colorado, Anthony S. Kim, Karl Meisel and Cathra Halabi

    Citation: BMC Neurology 2020 20:106

    Content type: Case report

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  35. Evoked potentials (EPs) are a measure of the conductivity of the central nervous system. They are used to monitor disease progression of multiple sclerosis patients. Previous studies only extracted a few varia...

    Authors: Jan Yperman, Thijs Becker, Dirk Valkenborg, Veronica Popescu, Niels Hellings, Bart Van Wijmeersch and Liesbet M. Peeters

    Citation: BMC Neurology 2020 20:105

    Content type: Research Article

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  36. Telemedicine improves the quality of acute stroke care in rural regions with limited access to specialized stroke care. We report the first 2 years’ experience of implementing a comprehensive telemedical strok...

    Authors: Katharina M. A. Gabriel, Steffi Jírů-Hillmann, Peter Kraft, Udo Selig, Viktoria Rücker, Johannes Mühler, Klaus Dötter, Matthias Keidel, Hassan Soda, Alexandra Rascher, Rolf Schneider, Mathias Pfau, Roy Hoffmann, Joachim Stenzel, Mohamed Benghebrid, Tobias Goebel…

    Citation: BMC Neurology 2020 20:104

    Content type: Research article

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  37. Road traffic accidents are known to be the main cause of traumatic brain injury (TBI). TBI is also a leading cause of death and disability. This study, by means of the idiographic approach (single-case experim...

    Authors: Samir Al-Adawi, Aziz Al-Naamani, Sanjay Jaju, Yahya M. Al-Farsi, Atsu S. S. Dorvlo, Ali Al-Maashani, Sara S. H. Al-Adawi, Ahmed A. Moustafa, Nasser Al-Sibani, Musthafa M. Essa, David T. Burke and M. Walid Qoronfleh

    Citation: BMC Neurology 2020 20:103

    Content type: Research article

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  38. Ruptured intracranial aneurysms are often associated with subarachnoid or intraparenchymal hemorrhage. However, the prevalence of subdural hemorrhage post aneurysmal rupture is low and rarely reported in scien...

    Authors: Abdulrahman Hamad Al-Abdulwahhab, Abdulaziz Mohammad Al-Sharydah, Sari Saleh Al-Suhibani, Abdullah Salman Almulhim, Obaied M. Al-Dhafeeri and Saeed A. Al-Jubran

    Citation: BMC Neurology 2020 20:102

    Content type: Case report

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  39. In adults, the anastomosis between carotid and vertebrobasilar arteries is usually the posterior communicating artery, sometimes the primitive trigeminal artery. In this case, the basilar artery fed the intern...

    Authors: Xiaogang Liu, Bing Li, Ying Liu, Hongliang Wu, Huilong Zhang, Lianwei Dou and Chuanyu Liu

    Citation: BMC Neurology 2020 20:97

    Content type: Case report

    Published on: