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  1. The morbidity and mortality of stroke is disproportionately high in developing countries owing to the poor health care system and poor neurologic interventions. Though a number of studies were conducted to est...

    Authors: Muluneh Alene, Moges Agazhe Assemie, Leltework Yismaw and Daniel Bekele Ketema

    Citation: BMC Neurology 2020 20:309

    Content type: Research article

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  2. Interleukin 36 (IL-36), as a gradually recognized cytokine, is involved in the occurrence and evolution of autoimmune diseases. Nevertheless, the relationship between myasthenia gravis (MG) and IL-36 is rarely...

    Authors: Qiu-Xia Zhang, Yue Li, Shu-Min Jiang, Lin-Jie Zhang, Ming Yi, Jing Wang, Yuan Qi, Li Yang and Chun-Sheng Yang

    Citation: BMC Neurology 2020 20:307

    Content type: Research article

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  3. Parkinson’s disease (PD) causes motor and nonmotor disorders in patients. Unlike aerobic training, potential adaptations from the practice of dance are less understood in PD, particularly compared with better ...

    Authors: Marcela dos Santos Delabary, Elren Passos Monteiro, Rebeca Gimenes Donida, Mariana Wolffenbuttel, Leonardo Alexandre Peyré-Tartaruga and Aline Nogueira Haas

    Citation: BMC Neurology 2020 20:305

    Content type: Research article

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  4. The present study aims to evaluate the performance and the clinical applicability of the Recognition of Stroke in the Emergency Department (ROSIER) scale via systematic review and meta-analysis.

    Authors: Fei Han, Chao Zuo and Guodong Zheng

    Citation: BMC Neurology 2020 20:304

    Content type: Research article

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  5. Perioperative cerebrospinal fluid (CSF) leakage is a major complication of pituitary adenomas transsphenoidal surgery. Lumbar drainage (LD) is a common method of treating CSF leakage. But whether intraoperativ...

    Authors: Jiahe Tan, Rui Song, Renzheng Huan, Ning Huang and Jin Chen

    Citation: BMC Neurology 2020 20:303

    Content type: Research article

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  6. Ischemic Moyamoya disease is one of the important causes of stroke, which leads to severe impairment in cognitive functions. This cognitive impairment occurs prior to stroke. However, the cognitive functions t...

    Authors: Ziqi Liu, Shihao He, Zongsheng Xu, Ran Duan, Li Yuan, Chu Xiao, Zhe Yi and Rong Wang

    Citation: BMC Neurology 2020 20:302

    Content type: Research article

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  7. Acceptance and Commitment Therapy (ACT), as a type of behavioral therapy, attempts to respond to changes in people’s performance and their relationship to events. ACT can affect sleep quality by providing tech...

    Authors: Nader Salari, Habibolah Khazaie, Amin Hosseinian-Far, Behnam Khaledi-Paveh, Hooman Ghasemi, Masoud Mohammadi and Shamarina Shohaimi

    Citation: BMC Neurology 2020 20:300

    Content type: Research article

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  8. With the growing awareness of restless legs syndrome (RLS), sensory disorders similar to RLS but initially confined to the arms, abdomen, and perineum have been reported. One of them is restless abdomen, which...

    Authors: Xi-Xi Wang, Xiao-Ying Zhu, Zan Wang, Jian-Wei Dong, William G. Ondo and Yun-Cheng Wu

    Citation: BMC Neurology 2020 20:298

    Content type: Research article

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  9. PDSAFE is an individually-tailored, physiotherapist-delivered, balance, strength and strategy training programme aimed at preventing falls among people with Parkinson’s. We evaluated the cost-effectiveness of ...

    Authors: Yiqiao Xin, Ann Ashburn, Ruth M. Pickering, Kim Chivers Seymour, Sophia Hulbert, Carolyn Fitton, Dorit Kunkel, Ioana Marian, Helen C. Roberts, Sarah E. Lamb, Victoria A. Goodwin, Lynn Rochester and Emma McIntosh

    Citation: BMC Neurology 2020 20:295

    Content type: Research article

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  10. The evidence on the efficacy of adipose derived stem cells (ADSCs) in the treatment of stroke is controversial. Therefore, the aim of present systematic review and meta-analysis is to evaluate the efficacy of ...

    Authors: Mahmoud Yousefifard, Jebreil Shamseddin, Asrin Babahajian and Arash Sarveazad

    Citation: BMC Neurology 2020 20:294

    Content type: Research article

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  11. New evidence on the efficacy and safety of dual antiplatelet therapy for secondary stroke prevention have been realized in the recent years. An updated meta analysis was done to determine the effect of the var...

    Authors: Christessa Emille Que Albay, Frederick Gavril D. Leyson and Federick C. Cheng

    Citation: BMC Neurology 2020 20:224

    Content type: Research article

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  12. Atherosclerosis of the internal carotid artery (ICA) is an important cause of ischemic stroke. Artery-to-artery embolism is the major stroke mechanism in patients with atherosclerotic carotid disease. This stu...

    Authors: Ho Geol Woo, Sung Hyuk Heo, Eui Jong Kim, Dae-il Chang, Tae Jin Song and Bum Joon Kim

    Citation: BMC Neurology 2020 20:288

    Content type: Research article

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  13. The blood-brain barrier has been a hindrance to developing blood-based diagnostic tests for dementias, as it limits the appearance of brain biomarkers in the blood. Our aim was to see if the natural opening of...

    Authors: Dennis W. Choi, Tae Song Kim, Young Soo Kim and Dong Jin Kim

    Citation: BMC Neurology 2020 20:293

    Content type: Research article

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  14. The diagnosis of Parkinson’s Disease (PD) remains a challenge and is currently based on the assessment of clinical symptoms. PD is also a heterogeneous disease with great variability in symptoms, disease cours...

    Authors: A. F. Wolters, M. Heijmans, S. Michielse, A. F. G. Leentjens, A. A. Postma, J. F. A. Jansen, D. Ivanov, A. A. Duits, Y. Temel and M. L. Kuijf

    Citation: BMC Neurology 2020 20:292

    Content type: Study protocol

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  15. Stress-induced childhood-onset neurodegeneration with variable ataxia and seizures (CONDSIAS) is an autosomal recessive disorder caused by defects in the ADP-Ribosylhydrolase Like 2 (ADPRHL2; OMIM: 618170) gene. ...

    Authors: Hajar Aryan, Ehsan Razmara, Dariush Farhud, Marjan Zarif-Yeganeh, Shaghayegh Zokaei, Seyed Abbas Hassani, Mahmoud Reza Ashrafi, Masoud Garshasbi and Ali Reza Tavasoli

    Citation: BMC Neurology 2020 20:291

    Content type: Case report

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  16. Spastic paraplegia type 30 (SPG30) caused by KIF1A mutations was first reported in 2011 and was initially considered a very rare autosomal recessive (AR) form. In the last years, thanks to the development of mass...

    Authors: G. E. Rudenskaya, V. A. Kadnikova, O. P. Ryzhkova, L. A. Bessonova, E. L. Dadali, D. S. Guseva, T. V. Markova, D. N. Khmelkova and A. V. Polyakov

    Citation: BMC Neurology 2020 20:290

    Content type: Research article

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  17. To evaluate the medium-and long-term effect of intravascular interventional therapy for symptomatic severe basilar artery stenosis supported by multimodal imaging.

    Authors: Yuanzhi Li, Zhenfa Li, Ligang Song, Weimin Xie, Xianghao Gong, Dongliang He and Xin Zhang

    Citation: BMC Neurology 2020 20:289

    Content type: Research article

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  18. Surgical treatment of anterior communicating artery (Acom) aneurysm is challenging due to anatomic complexity. We aimed to describe our experiences with endovascular treatment (EVT) of Acom aneurysms, and to ev.....

    Authors: Chang Ki Jang, Joonho Chung, Jae Whan Lee, Seung Kon Huh, Nak-Hoon Son and Keun Young Park

    Citation: BMC Neurology 2020 20:287

    Content type: Research article

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  19. Central sensitization is thought to be an important contributing factor in many chronic pain disorders. The Central Sensitization Inventory (CSI) is a patient-reported measure frequently used to assess symptom...

    Authors: Saurab Sharma, Jyoti Jha, Anupa Pathak and Randy Neblett

    Citation: BMC Neurology 2020 20:286

    Content type: Research article

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  20. Patients with vascular Ehlers-Danlos syndrome (EDS) occasionally suffer from arterial dissection. Eagle syndrome, which is caused by an elongated styloid process and also causes arterial dissection, is difficu...

    Authors: Hajime Ikenouchi, Masahito Takagi, Ayako Nishimura, Eriko Yamaguchi, Junpei Koge, Kozue Saito, Kazunori Toyoda and Masatoshi Koga

    Citation: BMC Neurology 2020 20:285

    Content type: Case report

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  21. Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT). Herein, we hypothesi...

    Authors: Yong-Won Kim, Sung-Il Sohn, Joonsang Yoo, Jeong-Ho Hong, Chang-Hyun Kim, Dong-Hun Kang, Yong-Sun Kim, Seong-Joon Lee, Ji Man Hong, Jin Wook Choi, Yang-Ha Hwang and Jin Soo Lee

    Citation: BMC Neurology 2020 20:284

    Content type: Research article

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  22. Although stent retriever (SR) is recommended as a frontline device of endovascular treatment (EVT) for embolic large artery occlusion causing acute ischemic stroke, contact aspiration (CA) device showed simila...

    Authors: Joonsang Yoo, Seong-Joon Lee, Jeong-Ho Hong, Yong-Won Kim, Ji Man Hong, Chang-Hyun Kim, Dong-Hun Kang, Jin Wook Choi, Yong-Sun Kim, Sung-Il Sohn, Yang-Ha Hwang and Jin Soo Lee

    Citation: BMC Neurology 2020 20:283

    Content type: Research article

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  23. Nonadherence to disease-modifying drugs (DMDs) for multiple sclerosis (MS) is associated with poorer clinical outcomes, including higher rates of relapse and disease progression, and higher medical resource us...

    Authors: Jacqueline A. Nicholas, Natalie C. Edwards, Roger A. Edwards, Anna Dellarole, Megan Grosso and Amy L. Phillips

    Citation: BMC Neurology 2020 20:281

    Content type: Research article

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  24. Ischemic stroke is a leading cause of morbidity and mortality. Thrombolytic therapy improves disability and survival rates; however, to be effective, it must be given within 4.5 h of onset. Moreover, thromboly...

    Authors: Jun Ni, Huisheng Chen, Guofang Chen, Yong Ji, Fei Yi, Zhuobo Zhang, Yi Yang, Jin Wu, Xueli Cai, Bei Shao, Jianfeng Wang, Yafang Liu, Deqin Geng, Xinhui Qu, Xiaohong Li, Yan Wei…

    Citation: BMC Neurology 2020 20:282

    Content type: Research article

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  25. Balanced Steady State Free Precession (b-SSFP) sequences and the newly developed Fast-Spin-Echo (FSE)-sequences enable an optimized visualization of neurovascular compression (NVC) in patients with trigeminal ...

    Authors: Sebastian Müller, Eya Khadhraoui, Ali Khanafer, Marios Psychogios, Veit Rohde and Levent Tanrikulu

    Citation: BMC Neurology 2020 20:279

    Content type: Research article

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  26. Variants in the SLC25A1 gene are associated with a severe neurometabolic disease, D-2- and L-2-hydroxyglutaric aciduria (D/L-2-HGA). A report in 2014 presented the first account of congenital myasthenic syndrome ...

    Authors: Wenhui Li, Min Zhang, Linmei Zhang, Yiyun Shi, Lei Zhao, Bingbing Wu, Xihua Li and Shuizhen Zhou

    Citation: BMC Neurology 2020 20:278

    Content type: Case report

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  27. Dopamine transporter (DAT) imaging may enable clinicians to discriminate idiopathic normal pressure hydrocephalus (iNPH) from other parkinsonian disorders. However, a specific pattern of dopaminergic loss in D...

    Authors: Jeong-Yoon Lee, Soo Bin Park, Mina Lee, Hyunjin Ju, Kayeong Im and Kyum-Yil Kwon

    Citation: BMC Neurology 2020 20:277

    Content type: Research article

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  28. There is growing evidence for proprioceptive dysfunction in patients with Parkinson’s disease (PD). The Lee Silvermann Voice Treatment-BIG therapy (LSVT-BIG), a special training program aiming at an increase o...

    Authors: Manuel Peterka, Thorsten Odorfer, Michael Schwab, Jens Volkmann and Daniel Zeller

    Citation: BMC Neurology 2020 20:276

    Content type: Research article

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  29. Headache and Attention Deficit Hyperactivity Disorder (ADHD) are two relatively common, neuropsychiatric conditions seen in children. Recent studies have shown an association between these two disorders, which...

    Authors: Udena Ruwindu Attygalle, Gemunu Hewawitharana and Champa Jayalakshmie Wijesinghe

    Citation: BMC Neurology 2020 20:275

    Content type: Research article

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  30. Real-world data on sufficient/insufficient response, and predictors of insufficient response, to acute treatments for migraine are limited in Japan. This study aimed to identify factors associated with insuffi...

    Authors: Koichi Hirata, Kaname Ueda, Wenyu Ye, Yongin Kim, Mika Komori, James Jackson, Sarah Cotton, Narayan Rajan and Tamas Treuer

    Citation: BMC Neurology 2020 20:274

    Content type: Research article

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  31. Restoring community walking remains a highly valued goal for persons recovering from traumatic incomplete spinal cord injury (SCI). Recently, studies report that brief episodes of low-oxygen breathing (acute i...

    Authors: Avantika Naidu, Denise M. Peters, Andrew Q. Tan, Stella Barth, Andrea Crane, Angela Link, Swapna Balakrishnan, Heather B. Hayes, Chloe Slocum, Ross D. Zafonte and Randy D. Trumbower

    Citation: BMC Neurology 2020 20:273

    Content type: Study protocol

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  32. Cerebral-cardiac syndrome, newly developed cardiac damage manifestations subsequent to cerebral injuries, is a common complication of stroke and leads to increased morbidity and mortality. The current study is...

    Authors: Haijuan Lian, Xiaomeng Xu, Xuhui Shen, Jinhua Chen, Dandan Mao, Yan Zhao and Meiqi Yao

    Citation: BMC Neurology 2020 20:272

    Content type: Research article

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  33. Cerebral vasospasm still results in high morbidity and mortality rates in patients after aneurysmal subarachnoid hemorrhage (SAH). The aim of this study was to establish a protocol for the management of vasosp...

    Authors: Chun-Ting Chen, Ching-Chang Chen, Alvin Yi-Chou Wang, Yi-Ming Wu, Shy-Chyi Chin, Po-Chuan Hsieh, Mun-Chun Yeap, Shih-Yuan Hsu and Ya-Jui Lin

    Citation: BMC Neurology 2020 20:271

    Content type: Research article

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  34. Stroke mimics account for up to one-third of acute stroke admissions and are a heterogeneous entity which pose diagnostic challenges. Diagnosing such patients is however crucial to avoid delays in treatment an...

    Authors: Sarah Shali Matuja, Khuzeima Khanbhai, Karim M. Mahawish and Patricia Munseri

    Citation: BMC Neurology 2020 20:270

    Content type: Research article

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  35. Acute ischemic stroke is a time-sensitive emergency where accurate diagnosis is required promptly. Due to time pressures, stroke mimics who present with similar signs and symptoms as acute ischemic stroke, pos...

    Authors: Tian Ming Tu, Guan Zhong Tan, Seyed Ehsan Saffari, Chee Keong Wee, David Jeremiah Ming Siang Chee, Camlyn Tan and Hoon Chin Lim

    Citation: BMC Neurology 2020 20:269

    Content type: Research article

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  36. The ultrasound based non-invasive ICP measurement method has been recently validated. Correlation of symptoms and signs of intracranial hypertension with actual ICP measurements in patients with large intracra...

    Authors: Jenny C. Kienzler, Rolandas Zakelis, Serge Marbacher, Sabrina Bäbler, Lucia Schwyzer, Elke Remonda and Javier Fandino

    Citation: BMC Neurology 2020 20:268

    Content type: Research article

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  37. Remote ischemic conditioning during cerebral ischemia (remote ischemic perconditioning, RIPerC) refers to the application of several cycles of brief ischemia and reperfusion (I/R) commonly to a limb, and it re...

    Authors: Francisco Purroy, Cristina García, Gerard Mauri, Cristina Pereira, Coral Torres, Daniel Vazquez-Justes, Mikel Vicente-Pascual, Ana Vena and Gloria Arque

    Citation: BMC Neurology 2020 20:266

    Content type: Research article

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  38. The level of function of instrumental activities of daily living (IADL) is crucial for a person’s autonomy. A clear understanding of the nature of IADL and its limitations in people with mild cognitive impairm...

    Authors: Marina Bruderer-Hofstetter, Sietske A. M. Sikkes, Thomas Münzer and Karin Niedermann

    Citation: BMC Neurology 2020 20:264

    Content type: Research article

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  39. Level of dependency after a stroke is important for long-term outcome in several aspects, but less is known about important predictors for outcome depending on functional dependency. The aim of the current stu...

    Authors: Emma Westerlind, Daniel Hörsell and Hanna C. Persson

    Citation: BMC Neurology 2020 20:263

    Content type: Research article

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  40. In this study, we explored whether the proposed short-echo-time magnitude (setMag) image derived from quantitative susceptibility mapping (QSM) could resemble NM-MRI image in substantia nigra (SN), by quantita...

    Authors: Xue Ling Liu, Li Qin Yang, Feng Tao Liu, Pu-Yeh Wu, Yong Zhang, Han Zhuang, Yong Hong Shi, Jian Wang, Dao Ying Geng and Yu Xin Li

    Citation: BMC Neurology 2020 20:262

    Content type: Research article

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  41. Although the criteria for acute migraine treatment and prevention have been well described, there are still unmet needs, general underuse and low benefits of preventive drugs.

    Authors: Marianna Delussi, Eleonora Vecchio, Giuseppe Libro, Silvia Quitadamo and Marina de Tommaso

    Citation: BMC Neurology 2020 20:256

    Content type: Research article

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