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BMC Neurology

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  1. Content type: Research article

    Alexander disease (AxD) is an astrogliopathy that predominantly affects the white matter of the central nervous system (CNS), and is caused by a mutation in the gene encoding the glial fibrillary acidic protei...

    Authors: So-Hyun Lee, Tai-Seung Nam, Kun-Hee Kim, Jin Hee Kim, Woong Yoon, Suk-Hee Heo, Min Jung Kim, Boo Ahn Shin, Ming-Der Perng, Hyon E. Choy, Jihoon Jo, Myeong-Kyu Kim and Seok-Yong Choi

    Citation: BMC Neurology 2017 17:175

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  2. Content type: Research article

    In recent years, shared decision making (SDM) has been promoted as a model to guide interactions between persons with MS and their neurologists to reach mutually satisfying decisions about disease management –...

    Authors: S. Michelle Driedger, Ryan Maier, Ruth Ann Marrie and Melissa Brouwers

    Citation: BMC Neurology 2017 17:176

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  3. Content type: Research article

    Adult neurogenesis persists through life at least in classic neurogenic niches. Neurogenesis has been previously described as reduced in neurodegenerative diseases. There is not much knowledge about is adult n...

    Authors: Lucía Galán, Ulises Gómez-Pinedo, Antonio Guerrero, Jose Manuel García-Verdugo and Jorge Matías-Guiu

    Citation: BMC Neurology 2017 17:173

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  4. Content type: Research article

    Maintaining patient adherence to disease modifying drugs in multiple sclerosis is a challenge, which can be improved by autoinjectors. The BETACONNECT® is a fully electronic autoinjector for the injection of i...

    Authors: Ingo Kleiter, Michael Lang, Judith Jeske, Christiane Norenberg, Barbara Stollfuß and Markus Schürks

    Citation: BMC Neurology 2017 17:174

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  5. Content type: Research article

    The cerebral subcortical deep gray matter nuclei (DGM) are a common, early, and clinically-relevant site of atrophy in multiple sclerosis (MS). Robust and reliable DGM segmentation could prove useful to evalua...

    Authors: Renxin Chu, Shelley Hurwitz, Shahamat Tauhid and Rohit Bakshi

    Citation: BMC Neurology 2017 17:172

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  6. Content type: Research article

    Patient adherence to treatment is key to preventing the worsening of neurological disability in multiple sclerosis (MS). The RebiSmart® autoinjector facilitates self-administration of subcutaneous interferon β...

    Authors: Chiara Zecca, Giulio Disanto, Sarah Mühl and Claudio Gobbi

    Citation: BMC Neurology 2017 17:171

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  7. Content type: Research article

    While neurogranin has no value as plasma biomarker for Alzheimer’s disease, it may be a potential blood biomarker for traumatic brain injury. This evokes the question whether there are changes in neurogranin l...

    Authors: Ann De Vos, Maria Bjerke, Raf Brouns, Naomi De Roeck, Dirk Jacobs, Lien Van den Abbeele, Kaat Guldolf, Henrik Zetterberg, Kaj Blennow, Sebastiaan Engelborghs and Eugeen Vanmechelen

    Citation: BMC Neurology 2017 17:170

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  8. Content type: Research article

    Conditioned pain modulation (CPM) evaluates the pain modulating effect of a noxious conditioning stimulus (CS) on another noxious test stimulus (TS), mostly based solely on subjective pain ratings. We used pai...

    Authors: Oliver Höffken, Özüm S. Özgül, Elena K. Enax-Krumova, Martin Tegenthoff and Christoph Maier

    Citation: BMC Neurology 2017 17:167

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  9. Content type: Research article

    Whether there are differences in pathogenesis among different types and subtypes of cerebral watershed infarction (WSI) is controversial since they have been combined into a single group in most previous studies.

    Authors: Yue Li, Man Li, Xiaoyu Zhang, Shuna Yang, Huimin Fan, Wei Qin, Lei Yang, Junliang Yuan and Wenli Hu

    Citation: BMC Neurology 2017 17:166

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  10. Content type: Research article

    In order to evaluate the impact of cilostazol on endothelial function, we compared the changes of flow-mediated dilation (FMD) between aspirin and cilostazol groups in patients with acute cerebral ischemia.

    Authors: Seong-Joon Lee, Jin Soo Lee, Mun Hee Choi, Sung Eun Lee, Dong Hoon Shin and Ji Man Hong

    Citation: BMC Neurology 2017 17:169

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  11. Content type: Research article

    Neuropathy is one of the major complications of type 2 diabetes mellitus. Our first aim was to determine the clinical characteristics of a population of diabetic patients with different types of neuropathy. Ou...

    Authors: Angélica Carbajal-Ramírez, Rebeca García-Macedo, Carlos Manlio Díaz-García, Carmen Sanchez-Soto, Araceli Méndez Padrón, Jorge Escobedo de la Peña, Miguel Cruz and Marcia Hiriart

    Citation: BMC Neurology 2017 17:161

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  12. Content type: Debate

    Cerebral amyloid angiopathy (CAA) is characterized by the deposition of ß-amyloid peptides (Aß) in and surrounding the wall of microvasculature in the central nervous system, together with parenchymal amyloid ...

    Authors: Jian-Ming Li, Li-Ling Huang, Fei Liu, Bei-Sha Tang and Xiao-Xin Yan

    Citation: BMC Neurology 2017 17:163

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  13. Content type: Research article

    Acute autonomic neuropathy (AAN) is rare disorder with anecdotal report, especially for childhood onset patients. Misdiagnosis or delays in treatment can always be found in clinical practice. We conducted this...

    Authors: Ling-Yu Pang, Chang-Hong Ding, Yang-Yang Wang, Li-Ying Liu, Qiao-Jun Li and Li-Ping Zou

    Citation: BMC Neurology 2017 17:164

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  14. Content type: Case report

    Non-traumatic, spontaneous subarachnoid hemorrhage occurs in approximately 85% of cases where there is a ruptured saccular aneurysm. An additional 10% of cases arise from non-aneurysmal peri-mesencephalic hemo...

    Authors: Anna Misyail Abdul Rashid and Mohamad Syafeeq Faeez Md Noh

    Citation: BMC Neurology 2017 17:165

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  15. Content type: Research article

    The insular cortex is not routinely removed in modified functional hemispherectomy due to the risk of injury to the main arteries and to deep structures. Our study evaluates the safety and usefulness of applyi...

    Authors: Gun-Ha Kim, Joo Hee Seo, James E. Baumgartner, Fatima Ajmal and Ki Hyeong Lee

    Citation: BMC Neurology 2017 17:162

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  16. Content type: Research article

    Multiple sclerosis (MS) is a demyelinating disease with a wide range of symptoms including walking impairment and neuropathic pain mainly represented by mechanical allodynia. Noteworthy, exercise preconditioni...

    Authors: Danielle Bernardes and Alexandre Leite Rodrigues Oliveira

    Citation: BMC Neurology 2017 17:160

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  17. Content type: Research article

    Standard echocardiography (SE) is an essential part of the routine diagnostic work-up after ischemic stroke (IS) and also serves for research purposes. However, access to SE is often limited. We aimed to asses...

    Authors: Peter Kraft, Anna Fleischer, Silke Wiedmann, Viktoria Rücker, Daniel Mackenrodt, Caroline Morbach, Uwe Malzahn, Christoph Kleinschnitz, Stefan Störk and Peter U. Heuschmann

    Citation: BMC Neurology 2017 17:159

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  18. Content type: Research article

    Previous studies have identified various treatment and patient characteristics that may be associated with higher hospital cost after spontaneous intracerebral hemorrhage (ICH); a devastating type of stroke. P...

    Authors: Adrian V. Specogna, Tanvir C. Turin, Scott B. Patten and Michael D. Hill

    Citation: BMC Neurology 2017 17:158

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  19. Content type: Research article

    Patients with multiple sclerosis (MS) receiving long-term, subcutaneous interferon β-1b (IFN β-1b; Extavia®) often experience injection-site reactions and injection-site pain, which together with other side-ef...

    Authors: Frank A. Hoffmann, Anastasiya Trenova, Miguel A. Llaneza, Johannes Fischer, Giacomo Lus, Dorothea von Bredow, Núria Lara, Elaine Lam, Marlies Van Hoef and Rajesh Bakshi

    Citation: BMC Neurology 2017 17:156

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  20. Content type: Case report

    Cryptococcal meningoencephalitis (CM) causes cerebral infarction, typically, lacunar infarction in the basal ganglia. However, massive cerebral infarction leading to death is rare and its pathophysiology is un...

    Authors: Yoshiteru Shimoda, Satoru Ohtomo, Hiroaki Arai, Takashi Ohtoh and Teiji Tominaga

    Citation: BMC Neurology 2017 17:157

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  21. Content type: Research article

    The association between multiple sclerosis (MS) and cancer has long been investigated with conflicting results. Several reports suggest an increased cancer risk among MS patients treated with immunosuppressant...

    Authors: Paolo Ragonese, Paolo Aridon, Giulia Vazzoler, Maria Antonietta Mazzola, Vincenzina Lo Re, Marianna Lo Re, Sabrina Realmuto, Simona Alessi, Marco D’Amelio, Giovanni Savettieri and Giuseppe Salemi

    Citation: BMC Neurology 2017 17:155

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  22. Content type: Case report

    Bi-allelic mutations in the genes Parkin (PARK2), PINK1 (PARK6) and DJ-1 (PARK7) are established causes of autosomal recessive early-onset Parkinson’s Disease (EOPD). PINK1 mutations are the second commonest caus...

    Authors: Brendan P. Norman, Steven J. Lubbe, Manuela Tan, Naomi Warren and Huw R. Morris

    Citation: BMC Neurology 2017 17:153

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  23. Content type: Case report

    Uremic Encephalopathy (UE) is a neurological complication associated with acute or chronic renal failure. Imaging findings of UE may present involvement of the basal ganglia, cortical or subcortical regions, a...

    Authors: Li-jing Jia, Zhen-zhen Qu, Xue-qian Zhang, Yu-juan Tian and Ying Wang

    Citation: BMC Neurology 2017 17:154

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  24. Content type: Case report

    Huntington’s disease (HD) is an autosomal dominant disorder, typically characterized by chorea due to a trinucleotide repeat expansion in the HTT gene, although the clinical manifestations of patients with juv...

    Authors: Shi-Shuang Cui, Ru-Jing Ren, Ying Wang, Gang Wang and Sheng-Di Chen

    Citation: BMC Neurology 2017 17:152

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