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  1. Mesial temporal lobe epilepsy (MTLE) is the most common form of focal epilepsy, which is frequently characterized by hippocampal sclerosis (HS). Accumulating studies have suggested widespread cortico-cortical ...

    Authors: Dongyan Wu, Feiyan Chang, Dantao Peng, Sheng Xie, Xiaoxuan Li and Wenjing Zheng

    Citation: BMC Neurology 2020 20:235

    Content type: Research article

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  2. Interictal epileptiform discharges (IEDs) have been proven to impair cognitive function. However, it is not clear whether IEDs disrupt academic performance in children with idiopathic epilepsy, and the contrib...

    Authors: Dazhi Cheng, Xiuxian Yan, Keming Xu, Xinlin Zhou and Qian Chen

    Citation: BMC Neurology 2020 20:233

    Content type: Research article

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  3. Partially thrombosed giant aneurysms at the basilar apex (BA) artery are challenging lesions with a poor prognosis if left untreated. Here we describe a rare case of extensive brain edema after growth of a sur...

    Authors: Daniel García-Pérez, Irene Panero, Carla Eiriz, Luis Miguel Moreno, Pablo M. Munarriz, Igor Paredes, Alfonso Lagares and José F. Alén

    Citation: BMC Neurology 2020 20:232

    Content type: Case report

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  4. By 2050, the prevalence of Alzheimer’s disease (AD) in the United States is predicted to reach 13.8 million. Despite worldwide research efforts, a cure for AD has not been identified. Thus, it is critical to i...

    Authors: Kyoung Shin Park, Alexis B. Ganesh, Nathaniel T. Berry, Yashonda P. Mobley, William B. Karper, Jeffrey D. Labban, Christopher N. Wahlheim, Tomika M. Williams, Laurie Wideman and Jennifer L. Etnier

    Citation: BMC Neurology 2020 20:231

    Content type: Study protocol

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  5. Intracranial necrotizing granulomatous space-occupying lesions are sparsely reported in literature. Variability in presenting symptomatology and radiographic features makes diagnostic work-up difficult.

    Authors: Kerilyn N. Godbe, Brian F. Saway, Evin L. Guilliams, John J. Entwistle and Robert W. Jarrett Jr

    Citation: BMC Neurology 2020 20:230

    Content type: Case report

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  6. Arterial thoracic outlet syndrome is a rare condition characterized by a subclavian artery pathology associated with a bone abnormality. It is rarely associated with thromboembolic stroke. The mechanism of cer...

    Authors: Adam Celier, Simon Chabay, Aurélien Maurizot, Frédéric Cochennec, Daniela Stanciu and Fernando Pico

    Citation: BMC Neurology 2020 20:229

    Content type: Case report

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  7. Recent studies have examined hypertrophic pachymeningitis as an IgG4-RD. However, there are no reports of immunoglobulin G4 (IgG4)-related hypertrophic pachymeningitis with polycystic subdural hygroma.

    Authors: Kazumichi Ota, Yoshihiko Nakazato, Risa Okuda, Ryu Yokoyama, Hitoshi Kawasaki, Naotoshi Tamura and Toshimasa Yamamoto

    Citation: BMC Neurology 2020 20:228

    Content type: Case report

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  8. The aim of this study was to assess the cognitive function of patients over 60 years old with meningioma using a domain-specific neuropsychological test and to investigate the relevant factors affecting pre-op...

    Authors: Min Ju Kang, Jung-Min Pyun, Min Jae Baek, Kihwan Hwang, Jung Ho Han, Young Ho Park, Chae-Yong Kim and SangYun Kim

    Citation: BMC Neurology 2020 20:225

    Content type: Research article

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  9. We evaluated severe pain-related adverse events (SAE) during the percutaneous dilatational tracheostomy (PDT) procedure performed by a neurointensivist and compared the outcomes with that of conventional surgi...

    Authors: Yong Oh Kim, Chi Ryang Chung, Chi-Min Park, Gee Young Suh and Jeong-Am Ryu

    Citation: BMC Neurology 2020 20:223

    Content type: Research article

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  10. Palato-pharyngo-laryngeal myoclonus, a variant of palatal myoclonus, is characterized by involuntary rhythmic movements of palatal, pharyngeal, and laryngeal muscles. Symptomatic palatal myoclonus is classical...

    Authors: Jamie L. Fleet, Ronelle Calver, Gihan C. Perera and Zhihui Deng

    Citation: BMC Neurology 2020 20:222

    Content type: Case report

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  11. Surgery is usually the treatment of choice for patients with cervical compressive myelopathy (CCM). Motor evoked potential (MEP) has proved to be helpful tool in evaluating intraoperative cervical spinal cord ...

    Authors: Shujie Wang, Zhifu Ren, Jia Liu, Jianguo Zhang and Ye Tian

    Citation: BMC Neurology 2020 20:221

    Content type: Research article

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  12. Thrombocytopenia (TP) has been shown to be an independent predictor of mortality in the intensive care unit (ICU) patients. Studies are lacking in the neurological ICU (NICU) population. The aim was to evaluat...

    Authors: Dawei Zhou, Zhimin Li, Lei Wu, Guangzhi Shi and Jianxin Zhou

    Citation: BMC Neurology 2020 20:220

    Content type: Research article

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  13. Almost half of the stroke patients admitted to geriatric rehabilitation has persisting problems after discharge. Currently, there is no evidence based geriatric rehabilitation programme available for older str...

    Authors: Tom P. M. M. Vluggen, Jolanda C. M. van Haastregt, Jeanine A. Verbunt, Caroline M. van Heugten and Jos M. G. A. Schols

    Citation: BMC Neurology 2020 20:219

    Content type: Research article

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  14. Several studies have reported the association between polymorphisms in Matrix metalloproteinases (MMPs) gene family and risk of Multiple sclerosis (MS). However, the results have been inconsistent and inconclu...

    Authors: Mina Mohammadhosayni, Arezou Khosrojerdi, Keivan Lorian, Saeed Aslani, Danyal Imani, Bahman Razi, Farhad Babaie and Shahram Torkamandi

    Citation: BMC Neurology 2020 20:218

    Content type: Research article

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  15. Poststroke depression can lead to functional dependence, cognitive impairment and reduced quality of life. The aim of this study was to evaluate the effects of a percutaneous mastoid electrical stimulator (PME...

    Authors: Taoli Lu, Lanying He, Bei Zhang, Jian Wang, Lili Zhang, Wei Wei Dong and Hao Yang

    Citation: BMC Neurology 2020 20:217

    Content type: Research article

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  16. The association between cytomegalovirus (CMV) and dementia remains controversial. Previous studies have suggested that CMV serostatus, as assessed by serum immunoglobulin G, plays a role in neurodegeneration w...

    Authors: Kyoung Hwa Lee, Da Eun Kwon, Kyung Do Han, Yeonju La and Sang Hoon Han

    Citation: BMC Neurology 2020 20:216

    Content type: Research article

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  17. Spastic ataxia of Charlevoix-Saguenay is a neurodegenerative condition due to mutations in the SACS gene and without a cure. Attempts to treatments are scarce and limited to symptomatic drugs.

    Authors: Ivana Ricca, Alessandra Tessa, Rosanna Trovato, Giacomo Maria Bacci and Filippo Maria Santorelli

    Citation: BMC Neurology 2020 20:215

    Content type: Case report

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  18. It is not well defined whether Guillain–Barré syndrome (GBS) patients with elevated serum creatine kinase (CK) levels have characteristic clinical features and are related to the subgroups of GBS.

    Authors: Takafumi Hosokawa, Hideto Nakajima, Taiki Sawai, Yoshitsugu Nakamura, Eri Sano, Akihiro Tsukahara, Kiichi Unoda, Shimon Ishida, Sadaki Sakane, Fumiharu Kimura and Shigeki Arawaka

    Citation: BMC Neurology 2020 20:214

    Content type: Research article

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  19. Routine test of cerebrospinal fluid (CSF), such as glucose concentrations, chloride ion, protein and leukocyte, as well as color, turbidity and clot, were important indicators for intracranial infection. Howev...

    Authors: Tiantian Zhai, Zhong lian Fu, Yan bing Qiu, Qiang Chen, Dong Luo and Kaisen Chen

    Citation: BMC Neurology 2020 20:213

    Content type: Research article

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  20. DL-3-n-butylphthalide (NBP) was demonstrated to increase the cerebral blood flow (CBF) in the animal models, but there are no clinic studies to verify this. We aimed to explore the effect of NBP on improving c...

    Authors: Dawei Chen, Yanwei Yin, Jin Shi, Fen Yang, Kehua Wang, Faguo Zhao, Wenping Li and Bin Li

    Citation: BMC Neurology 2020 20:212

    Content type: Research article

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  21. Vestibular migraine, a kind of acute vestibular syndrome, leads to both migraines and vertigo symptoms in a single patient. The occurrence of vestibular migraine has shown an obvious increase in female groups ...

    Authors: Ying Xin, Junyi Fu, Longchang Xie, Jie Yang and Guanhao Ke

    Citation: BMC Neurology 2020 20:211

    Content type: Case report

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  22. Concussion is the most common type of TBI, yet reliable objective measures related to these injuries and associated recovery processes remain elusive, especially in military personnel. The purpose of this stud...

    Authors: Katie A. Edwards, Jessica M. Gill, Cassandra L. Pattinson, Chen Lai, Misha Brière, Nicholas J. Rogers, Denise Milhorn, Jonathan Elliot and Walter Carr

    Citation: BMC Neurology 2020 20:209

    Content type: Research article

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  23. Cerebellar degeneration as a consequence of a malignancy is a rare condition most commonly related to the presence of anti-Yo, anti-Hu, and anti-Tr/DNER antibodies. In recent years, several reports have indica...

    Authors: Philipp A. Loehrer, Lars Timmermann, Anika Pehl, Corinna I. Bien, Andreas Pfestroff and David J. Pedrosa

    Citation: BMC Neurology 2020 20:208

    Content type: Case report

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  24. Homozygous frameshift mutation in RUBCN (KIAA0226), known to result in endolysosomal machinery defects, has previously been reported in a single Saudi family with autosomal recessive spinocerebellar ataxia (Sa...

    Authors: Mohammed Z. Seidahmed, Muddathir H. Hamad, Albandary AlBakheet, Salah A. Elmalik, Abdulmajeed AlDrees, Jumanah Al-Sufayan, Ibrahim Alorainy, Ibrahim M. Ghozzi, Dilek Colak, Mustafa A. Salih and Namik Kaya

    Citation: BMC Neurology 2020 20:207

    Content type: Case report

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  25. Stroke burden in young adults is growing associated with unique risk factors and devastating outcomes. We aimed to investigate the magnitude, risk factors and outcomes of first ever stroke in young adults ≤45 ...

    Authors: Sarah Shali Matuja, Patricia Munseri and Khuzeima Khanbhai

    Citation: BMC Neurology 2020 20:206

    Content type: Research article

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  26. Multiple sclerosis (MS) causes significant economic burden to the patients, families, health systems and society. This study aimed to estimate the annual economic costs incurred by patients with multiple scler...

    Authors: Ali Imani, Farid Gharibi, Ali Khezri, Nasrin Joudyian and Koustuv Dalal

    Citation: BMC Neurology 2020 20:205

    Content type: Research article

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  27. Cognitive dysfunction affects up to 70% of people with progressive MS (PMS). It can exert a deleterious effect on activities of daily living, employment and relationships. Preliminary evidence suggests that pe...

    Authors: Anthony Feinstein, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy Chiaravalloti, Ulrik Dalgas, John DeLuca, Peter Feys, Massimo Filippi, Jennifer Freeman, Cecilia Meza, Matilde Inglese, Robert W. Motl, Maria Assunta Rocca, Brian M. Sandroff, Amber Salter…

    Citation: BMC Neurology 2020 20:204

    Content type: Study protocol

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  28. To our knowledge, the exposed nerve roots in thoracic spine are usually sacrificed to facilitate osteotomy during posterior vertebral column resection (PVCR) for severe spinal deformity. Currently we report a ...

    Authors: Shujie Wang, Zhifu Ren, Zhen Yang and Jianguo Zhang

    Citation: BMC Neurology 2020 20:203

    Content type: Case report

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  29. A high multiple sclerosis activity while on alemtuzumab is rather uncommon compared to moderate-efficacy drugs. The purpose of this case report is to present a case of a 37-year-old female patient with bronchi...

    Authors: Martin Vališ, Pavel Ryška, Simona Halúsková, Blanka Klímová and Zbyšek Pavelek

    Citation: BMC Neurology 2020 20:202

    Content type: Case report

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  30. Stress cardiomyopathy (Takotsubo cardiomyopathy) is very rare in the central nervous system (CNS) demyelinating disorders. Although this dysfunction of the heart-brain axis has been reported in several case se...

    Authors: Sungsik An, Hyeo-il Ma, Jooyeon Song, Hong-Mi Choi and Young Eun Kim

    Citation: BMC Neurology 2020 20:201

    Content type: Case report

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  31. Direct evidence of intimal flaps, double lumen and intramural haematomas (IMH) is difficult to detect on conventional angiography in most intracranial vertebrobasilar dissecting aneurysms (VBDAs). Our purpose ...

    Authors: Xianjin Zhu, Hancheng Qiu, Ferdinand K. Hui, Yiqun Zhang, Yun-e Liu, Fengyuan Man and Wei-Jian Jiang

    Citation: BMC Neurology 2020 20:199

    Content type: Research article

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  32. We investigated the clinical course of patients with prolonged disorders of consciousness (PDoC), predictors of emergence from PDoC (EDoC), and the temporal dynamics of six neurobehavior domains based on the J...

    Authors: Hoo Young Lee, Jung Hyun Park, Ae Ryoung Kim, Misun Park and Tae-Woo Kim

    Citation: BMC Neurology 2020 20:198

    Content type: Research article

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  33. Acute ischemic stroke attack with and without a recent TIA may differ in clinical risk factors, and this may affect treatment outcomes following thrombolytic therapy. We examined whether the odds of exclusion ...

    Authors: Nicolas Poupore, Dan Strat, Tristan Mackey, Ashley Snell and Thomas Nathaniel

    Citation: BMC Neurology 2020 20:197

    Content type: Research article

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  34. Pathogenic variants in the FKRP gene cause impaired glycosylation of α-dystroglycan in muscle, producing a limb-girdle muscular dystrophy with cardiomyopathy. Despite advances in understanding the pathophysiol...

    Authors: Doris G. Leung, Alex E. Bocchieri, Shivani Ahlawat, Michael A. Jacobs, Vishwa S. Parekh, Vladimir Braverman, Katherine Summerton, Jennifer Mansour, Genila Bibat, Carl Morris, Shannon Marraffino and Kathryn R. Wagner

    Citation: BMC Neurology 2020 20:196

    Content type: Research article

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  35. The prevalence of Multiple Sclerosis (MS) has been increasing worldwide and the north–south gradient of prevalence may be disappearing in the Northern hemisphere. The few previous prevalence studies performed ...

    Authors: Mariana Branco, Ivânia Alves, Ana Martins da Silva, Joaquim Pinheiro, Maria José Sá, Inês Correia, Lívia Sousa, Eva Brandão, Carlos Veira, Bernardo Gomes and Luis Ruano

    Citation: BMC Neurology 2020 20:195

    Content type: Research article

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  36. Injection-site reactions have been reported with biologicals. In this post hoc analysis of Phase 3 studies in participants with migraine, we provide a comprehensive overview and detailed summary of injection-s...

    Authors: Virginia L. Stauffer, Shufang Wang, Jo Bonner, ByungKun Kim, Rohit Bhandari, Kathleen A. Day and Angelo Camporeale

    Citation: BMC Neurology 2020 20:194

    Content type: Research article

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  37. Cognitive impairment is common in patients with multiple sclerosis (MS). Accurate and repeatable measures of cognition have the potential to be used as markers of disease activity.

    Authors: Seyed-Mahdi Khaligh-Razavi, Maryam Sadeghi, Mahdiyeh Khanbagi, Chris Kalafatis and Seyed Massood Nabavi

    Citation: BMC Neurology 2020 20:193

    Content type: Research article

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  38. To explore the underlying mechanisms leading to the occurrence of hyponatremia and enhanced urinary sodium excretion in brain trauma patients using sodium balance and urinary biochemical analysis.

    Authors: Alexandre Lannou, Cedric Carrie, Sebastien Rubin, Gregoire Cane, Vincent Cottenceau, Laurent Petit and Matthieu Biais

    Citation: BMC Neurology 2020 20:190

    Content type: Research article

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  39. Endovascular therapy (EVT) is increasingly used to improve cerebral reperfusion after moderate-to-severe acute ischemic stroke (AIS). However, the influence of hemodynamic factors on clinical outcome is still ...

    Authors: Ge Tian, Zhong Ji, Kaibin Huang, Zhenzhou Lin, Suyue Pan and Yongming Wu

    Citation: BMC Neurology 2020 20:189

    Content type: Research article

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  40. To explore the feasibility of the metrics of diffusion kurtosis imaging (DKI) for investigations of the microstructural changes of spinal cord injury in patients with degenerative cervical myelopathy (DCM) and...

    Authors: Zhuohang Liu, Bingyang Bian, Gang Wang, Cheukying Tian, Zhenshan Lv, Zhiqing Shao and Dan Li

    Citation: BMC Neurology 2020 20:185

    Content type: Research article

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  41. Pisa syndrome (PS) is characterized by an abnormally sustained posture, with flexion of the body and head to one side and slight rotation of the trunk. Although PS most commonly arises as an adverse effect of ...

    Authors: Yu Mimura, Shin Kurose, Taketo Takata, Hajime Tabuchi, Masaru Mimura and Michitaka Funayama

    Citation: BMC Neurology 2020 20:183

    Content type: Case report

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  42. To describe the clinical phenotype of paroxysmal extreme pain disorder, an autosomal dominant condition in four members in one family with the mutation NM_002977.3:c.3892G > T (p.Val1298Phe) in the SCN9A gene. Cl...

    Authors: Adam Stępień, Daria Sałacińska, Jacek Staszewski, Marta Durka-Kęsy and Jan Dobrogowski

    Citation: BMC Neurology 2020 20:182

    Content type: Case report

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