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  1. There is a need for greater understanding of the impact of multiple sclerosis (MS) from the perspective of individuals with the condition. The South West Impact of MS Project (SWIMS) has been designed to impro...

    Authors: John P Zajicek, Wendy M Ingram, Jane Vickery, Siobhan Creanor, Dave E Wright and Jeremy C Hobart

    Citation: BMC Neurology 2010 10:88

    Content type: Research article

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  2. Behavioural and psychological symptoms of dementia (BPSD) are non-cognitive symptoms commonly associated to Alzheimer's disease (AD). The characterization of the clinical profile of AD patients might help to b...

    Authors: Manuel Fernández, Ana L Gobartt and Montse Balañá

    Citation: BMC Neurology 2010 10:87

    Content type: Research article

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  3. Rotigotine is a unique dopamine agonist with activity across D1 through D5 receptors as well as select adrenergic and serotonergic sites. This study reports the 2-year follow-up safety and efficacy data of an ...

    Authors: Birgit Högl, Wolfgang H Oertel, Karin Stiasny-Kolster, Peter Geisler, Heike Beneš, Diego García-Borreguero, Claudia Trenkwalder, Werner Poewe, Erwin Schollmayer and Ralf Kohnen

    Citation: BMC Neurology 2010 10:86

    Content type: Research article

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  4. The Freezing of Gait Questionnaire (FOGQ) was developed in response to the difficulties of observing and quantifying freezing of gait (FOG) clinically as well as in laboratory settings. However, as the FOGQ is...

    Authors: Maria H Nilsson, Gun-Marie Hariz, Klas Wictorin, Michael Miller, Lars Forsgren and Peter Hagell

    Citation: BMC Neurology 2010 10:85

    Content type: Research article

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  5. Shoulder pain is a common complication of a stroke which can impede participation in rehabilitation programs and has been associated with poorer outcomes. The evidence base for current medical and therapeutic ...

    Authors: Zoe A Allen, E Michael Shanahan and Maria Crotty

    Citation: BMC Neurology 2010 10:83

    Content type: Study protocol

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  6. Elevated serum uric acid (SUA) levels can enhance its antioxidant prosperities and reduce the occurrence of cerebral infarction. Significantly elevated SUA levels have been associated with a better prognosis i...

    Authors: Bin Zhang, Cong Gao, Ning Yang, WeiZhi Zhang, XingWang Song, JianRui Yin, ShuXiang Pu, YongHong Yi and QingChun Gao

    Citation: BMC Neurology 2010 10:82

    Content type: Research article

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  7. This study aims to investigate and compare the conduction parameters of nerve bundles in the ulnar nerve that innervates the forearm muscles and hand muscles; routine electromyography study merely evaluates th...

    Authors: Attila Oğuzhanoğlu, Sibel Güler, Mustafa Çam and Eylem Değirmenci

    Citation: BMC Neurology 2010 10:81

    Content type: Research article

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  8. The syndrome of the sinking skin flap (SSSF) with delayed sensorimotor deficits after craniectomy is not well known and often neglected. Among various postulated causes, there is evidence that disturbed brain ...

    Authors: Andre Kemmling, Thomas Duning, Lars Lemcke, Thomas Niederstadt, Jens Minnerup, Heike Wersching and Martin Marziniak

    Citation: BMC Neurology 2010 10:80

    Content type: Case report

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  9. The purpose of this study was to investigate the pattern of distribution of risk factors for stroke and the 10-year probability of stroke by the Framingham risk score in hypertensive patients visiting private ...

    Authors: Cheol Ung Choi and Chang Gyu Park

    Citation: BMC Neurology 2010 10:78

    Content type: Research article

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  10. The rate of recovery from the vegetative state (VS) is low. Currently, little is known of the mechanisms and cerebral changes that accompany those relatively rare cases of good recovery. Here, we combined func...

    Authors: Davinia Fernández-Espejo, Carme Junque, Damian Cruse, Montserrat Bernabeu, Teresa Roig-Rovira, Neus Fábregas, Eva Rivas and Jose M Mercader

    Citation: BMC Neurology 2010 10:77

    Content type: Research article

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  11. Type 2 Diabetes Mellitus (T2DM) and diabetic symmetrical polyneuropathy (DSP) impact multiple modalities of sensation including light touch, temperature, position sense and vibration perception. No study to da...

    Authors: Benjamin S Boyd, Linda Wanek, Andrew T Gray and Kimberly S Topp

    Citation: BMC Neurology 2010 10:75

    Content type: Research article

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  12. Within a multi-centre randomised controlled trial in three nursing homes, a process evaluation of a mental practice intervention was conducted. The main aims were to determine if the intervention was performed...

    Authors: Susy M Braun, Jolanda C van Haastregt, Anna J Beurskens, Alexandra I Gielen, Derick T Wade and Jos M Schols

    Citation: BMC Neurology 2010 10:74

    Content type: Research article

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  13. Despite extensive research, no reliable biological marker for chronic fatigue syndrome (CFS) has yet been identified. However, hyperactivation of melanotrophs in the pituitary gland and increased levels of pla...

    Authors: Nobue Shishioh-Ikejima, Tokiko Ogawa, Kouzi Yamaguti, Yasuyoshi Watanabe, Hirohiko Kuratsune and Hiroshi Kiyama

    Citation: BMC Neurology 2010 10:73

    Content type: Research article

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  14. Cerebrovascular disease is the second commonest cause of death, and over a third of stroke deaths occur in developing countries. To fulfil the current gap on data, this systematic review is focused on the freq...

    Authors: Akram A Hosseini, Davood Sobhani-Rad, Kavian Ghandehari and Hani TS Benamer

    Citation: BMC Neurology 2010 10:72

    Content type: Research article

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  15. Human serum paraoxonase 1 (PON1) plays a major role in the metabolism of several organophosphorus compounds. The enzyme is encoded by the polymorphic gene PON1, located on chromosome 7q21.3. Aiming to identify ge...

    Authors: Carmen Martínez, José A Molina, Hortensia Alonso-Navarro, Félix J Jiménez-Jiménez, José AG Agúndez and Elena García-Martín

    Citation: BMC Neurology 2010 10:71

    Content type: Research article

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  16. Many patients with Parkinson's disease (PD) lead a sedentary lifestyle. Promotion of physical activities may beneficially affect the clinical presentation of PD, and perhaps even modify the course of PD. Howev...

    Authors: Marlies van Nimwegen, Arlène D Speelman, Katrijn Smulders, Sebastiaan Overeem, George F Borm, Frank JG Backx, Bastiaan R Bloem and Marten Munneke

    Citation: BMC Neurology 2010 10:70

    Content type: Study protocol

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  17. Measuring quality of life (QOL) helps to delineate mechanisms underlying the interaction of disease and psychosocial factors. In adults, epileptic foci in the left temporal lobe led to lower QOL and higher dep...

    Authors: Krystyna A Mathiak, Małgorzata Łuba, Klaus Mathiak, Katarzyna Karzel, Tomasz Wolańczyk, Elżbieta Szczepanik and Paweł Ostaszewski

    Citation: BMC Neurology 2010 10:69

    Content type: Research article

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  18. In posterior cortical atrophy (PCA), there is a progressive impairment of high-level visual functions and parietal damage, which might predict the occurrence of visual neglect. However, neglect may pass undete...

    Authors: Katia Andrade, Dalila Samri, Marie Sarazin, Leonardo C de Souza, Laurent Cohen, Michel Thiebaut de Schotten, Bruno Dubois and Paolo Bartolomeo

    Citation: BMC Neurology 2010 10:68

    Content type: Research article

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  19. Depressive disorders are frequent in epilepsy and associated with reduced seizure control. Almost 50% of interictal depressive disorders have to be classified as atypical depressions according to DSM-4 criteri...

    Authors: Arne E Vaaler, Gunnar Morken, Valentina C Iversen, Daniel Kondziella and Olav M Linaker

    Citation: BMC Neurology 2010 10:67

    Content type: Research article

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  20. There is an ongoing debate whether essential tremor (ET) represents a monosymptomatic disorder or other neurologic symptoms are compatible with the diagnosis of ET. Many patients with clinically definite ET de...

    Authors: Peter Hedera, Fenna T Phibbs, John Y Fang, Michael K Cooper, P David Charles and Thomas L Davis

    Citation: BMC Neurology 2010 10:66

    Content type: Research article

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  21. Metabolic Syndrome (MetSd) is a cluster of vascular risk factors that may influence cerebrovascular pathology during aging. Recently, microstructural white matter (WM) changes detected by diffusion tensor imag...

    Authors: Bàrbara Segura, María Ángeles Jurado, Núria Freixenet, Núria Bargalló, Carme Junqué and Adrià Arboix

    Citation: BMC Neurology 2010 10:64

    Content type: Research article

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  22. Catheter ablation of the pulmonary veins has become accepted as a standard therapeutic approach for symptomatic paroxysmal atrial fibrillation (AF). However, there is some evidence for an ablation associated (...

    Authors: Karl Georg Haeusler, Lydia Koch, Juliane Ueberreiter, Matthias Endres, Heinz-Peter Schultheiss, Peter U Heuschmann, Alexander Schirdewan and Jochen B Fiebach

    Citation: BMC Neurology 2010 10:63

    Content type: Study protocol

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  23. National data on dementia prevalence are not always available, yet it may be possible to obtain estimates from large surveys that include dementia screening instruments. In Australia, many of the dementia prev...

    Authors: Kaarin J Anstey, Richard A Burns, Carole L Birrell, David Steel, Kim M Kiely and Mary A Luszcz

    Citation: BMC Neurology 2010 10:62

    Content type: Research article

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  24. Animal and human studies suggest that stress experienced early in life has detrimental consequences on brain development, including brain regions involved in cognitive function. Cognitive changes are cardinal ...

    Authors: Matthias Majer, Urs M Nater, Jin-Mann S Lin, Lucile Capuron and William C Reeves

    Citation: BMC Neurology 2010 10:61

    Content type: Research article

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  25. The disease burden of human immunodeficiency virus (HIV) - acquired immunodeficiency syndrome (AIDS) is highest in sub-Saharan Africa but there are few studies on the associated neurocognitive disorders in thi...

    Authors: Georgette D Kanmogne, Callixte T Kuate, Lucette A Cysique, Julius Y Fonsah, Sabine Eta, Roland Doh, Dora M Njamnshi, Emilienne Nchindap, Donald R Franklin Jr, Ronald J Ellis, John A McCutchan, Fidele Binam, Dora Mbanya, Robert K Heaton and Alfred K Njamnshi

    Citation: BMC Neurology 2010 10:60

    Content type: Research article

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  26. Cerebrotendinous xanthomatosis (CTX) is a rare genetic disorder. Recent studies show that brain damage in CTX patients extends beyond the abnormalities observed on conventional magnetic resonance imaging (MRI)...

    Authors: Chiung-Chih Chang, Chun-Chung Lui, Jiun-Jie Wang, Shu-Hua Huang, Cheng-Hsien Lu, Ching Chen, Chih-Feng Chen, Min-Chien Tu, Chi-Wei Huang and Wen-Neng Chang

    Citation: BMC Neurology 2010 10:59

    Content type: Research article

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  27. Use of Botulinum toxin-A (BoNT-A) for treatment of upper limb spasticity in children with cerebral palsy has become routine clinical practice in many paediatric treatment centres worldwide. There is now high-l...

    Authors: Brian J Hoare, Christine Imms, Hyam Barry Rawicki and Leeanne Carey

    Citation: BMC Neurology 2010 10:58

    Content type: Study protocol

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  28. In facioscapulohumeral dystrophy (FSHD) muscle function is impaired and declines over time. Currently there is no effective treatment available to slow down this decline. We have previously reported that loss ...

    Authors: Nicoline BM Voet, Gijs Bleijenberg, George W Padberg, Baziel GM van Engelen and Alexander CH Geurts

    Citation: BMC Neurology 2010 10:56

    Content type: Study protocol

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  29. As a continuation of the previous findings in human fetuses, accidental finding of an accessory vascular component in the posterior part of CAC of human adult cadavers inspired the authors to present and compa...

    Authors: Ljiljana Vasović, Milena Trandafilović, Ivan Jovanović, Aleksandra Antović, Jovan Stojanović, Miodrag Zdravković and Miroslav Milić

    Citation: BMC Neurology 2010 10:53

    Content type: Case report

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  30. Cerebral palsy (CP) may cause severe spasticity, requiring neurosurgical procedures. The most common neurosurgical procedures are continuous infusion of intrathecal baclofen and selective dorsal rhizotomy. Bot...

    Authors: Georges F Vles, Johan S Vles, Maarten van Kleef, Jan van Zundert, Heleen M Staal, Wim E Weber, Lodewijk W van Rhijn, Dan Soudant, H Kerr Graham and Anton J de Louw

    Citation: BMC Neurology 2010 10:52

    Content type: Research article

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  31. The metabolism of amyloid precursor protein (APP) and β-amyloid (Aβ) is widely studied in Alzheimer's disease, where Aβ deposition and plaque development are essential components of the pathogenesis. However, ...

    Authors: Niklas Mattsson, Daniel Bremell, Rolf Anckarsäter, Kaj Blennow, Henrik Anckarsäter, Henrik Zetterberg and Lars Hagberg

    Citation: BMC Neurology 2010 10:51

    Content type: Research article

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  32. Transient ischemic attack (TIA) patients are at a high vascular risk. Recently the ABCD2 score was validated for evaluating short-term stroke risk after TIA. We assessed the value of this score to predict the vas...

    Authors: Katrin Holzer, Regina Feurer, Suwad Sadikovic, Lorena Esposito, Angelina Bockelbrink, Dirk Sander, Bernhard Hemmer and Holger Poppert

    Citation: BMC Neurology 2010 10:50

    Content type: Research article

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  33. Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants for the treatment of depression in patients with Parkinson's Disease (PD) but data on their efficacy are controv...

    Authors: Petros Skapinakis, Eleni Bakola, Georgia Salanti, Glyn Lewis, Athanasios P Kyritsis and Venetsanos Mavreas

    Citation: BMC Neurology 2010 10:49

    Content type: Research article

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  34. Data from different studies suggest a favourable association between pretreatment with statins or hypercholesterolemia and outcome after ischaemic stroke. We examined whether there were differences in in-hospi...

    Authors: Adrià Arboix, Luis García-Eroles, Montserrat Oliveres, Cecília Targa, Miquel Balcells and Joan Massons

    Citation: BMC Neurology 2010 10:47

    Content type: Research article

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  35. Neuromyelitis optica (NMO) is an inflammatory demyelinating disease that predominantly affects the optic nerves and the spinal cord, and is possibly mediated by an immune mechanism distinct from that of multip...

    Authors: Hideto Nakajima, Takafumi Hosokawa, Masakazu Sugino, Fumiharu Kimura, Jun Sugasawa, Toshiaki Hanafusa and Toshiyuki Takahashi

    Citation: BMC Neurology 2010 10:45

    Content type: Research article

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  36. Anti-epileptic drugs (AEDs) are frequently prescribed to persons with HIV/AIDS receiving combination antiretroviral therapy (cART) although the extent of AED use and their interactions with cART are uncertain....

    Authors: Kathy Lee, Pornpun Vivithanaporn, Reed A Siemieniuk, Hartmut B Krentz, Ferdinand Maingat, M John Gill and Christopher Power

    Citation: BMC Neurology 2010 10:44

    Content type: Research article

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  37. Fatigue is one of the most commonly reported and debilitating symptoms of multiple sclerosis (MS); approximately two-thirds of people with MS consider it to be one of their three most troubling symptoms. It ma...

    Authors: Peter W Thomas, Sarah Thomas, Paula Kersten, Rosemary Jones, Alison Nock, Vicky Slingsby, Colin Green, Roger Baker, Kate Galvin and Charles Hillier

    Citation: BMC Neurology 2010 10:43

    Content type: Study protocol

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  38. Despite worldwide recognition of the burden of dementia, no epidemiological data is yet available in Portugal. The objective of this study is to estimate the prevalence and describe the pattern of cognitive im...

    Authors: Belina Nunes, Ricardo D Silva, Vitor T Cruz, Jose M Roriz, Joana Pais and Maria C Silva

    Citation: BMC Neurology 2010 10:42

    Content type: Research article

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  39. Genetic factors may play a role in susceptibility to spontaneous deep intracerebral hemorrhage (SDICH). Previous studies have shown that TNF-α gene variation was associated with risks of subarachnoid hemorrhage i...

    Authors: Yi-Chun Chen, Fen-Ju Hu, Phoebe Chen, Yih-Ru Wu, Hsiu-Chuan Wu, Sien-Tsong Chen, Guey-Jen Lee-Chen and Chiung-Mei Chen

    Citation: BMC Neurology 2010 10:41

    Content type: Research article

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  40. Despite the cardiovascular etiology of stroke, exercise and risk factor modification programs akin to cardiac rehabilitation (CR) are not available. This study aimed to establish the feasibility of adapting a ...

    Authors: Ada Tang, Susan Marzolini, Paul Oh, William E McIlroy and Dina Brooks

    Citation: BMC Neurology 2010 10:40

    Content type: Research article

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  41. PC plays an important role in early diagnosis of health disorders, particularly migraine, due to the financial impact of this disease for the society and its impact on patients' quality of life. The aim of the...

    Authors: Miguel J Láinez, Jesús Castillo, Manuel Domínguez, Gemma Palacios, Silvia Díaz and Javier Rejas

    Citation: BMC Neurology 2010 10:39

    Content type: Research article

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