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Table 1 Baseline characteristics of ICH Cohort (n = 40)

From: Copeptin is associated with mortality and outcome in patients with acute intracerebral hemorrhage

 

Survivors

Non-Survivors

p

 

(n = 34)

(n = 6)

 

Demographics

   

Age (years)

69.5 (61.5 - 75.8)

80 (73.3 - 82.3)

0.06

Gender (Female)

38% (13)

80% (5)

0.04

Clinical parameters

   

GCS*

15 (14-15)

10 (4-13)

0.009

Charlson Index

1 (0-1)

1.5 (1-2)

0.18

Body Temperature (C°)

37.1 (36.7-37.4)

36.0 (35.9-37.5)

0.32

Hematoma Volume in ml

13 (5-30)

69 (60-75)

0.003

Hypertension

67.7% (23)

100% (6)

0.444

Drugs (antiplatelets, anticoagulants)

26.5% (9)

0

NA

ICH Score

1 (0-1)

3 (2.5-4)

0.002

ICH Grading Scale

7 (7-8)

9.5 (9-11)

0.004

Location

   

   Basal ganglia

44.1% (15)

50% (3)

0.75

   Lobar

47.1% (16)

50% (3)

0.72

   Infratentorial

8.8% (3)

0

NA§

Presence of IVH†

20.6% (7)

33.3% (2)

0.602

Operation

   

   Surgical hematoma evacuation

8.8% (3)

16.7% (1)

0.656

   EVD‡ Placement

8.8% (3)

0

NA

Laboratory Values

   

Sodium (mmol/l)

138 (136-141)

139 (132-141)

0.89

Osmolarity (mosml/l)

297 (293-301)

292 (283-300)

0.53

Glucose (mmol/l)

6.6 (5.8-7.8)

7.7 (6.1-8.4)

0.64

White blood count (×109/l)

9.5 (6.7-11.6)

8.7 (7.5-8.8)

0.58

C-reactive Protein (mg/l)

6 (3-18)

12 (3-81)

0.54

Copeptin level (nmol/l)

12.9 (5.2- 42.8)

179.0 (33.7-566.0)

0.003

  1. Values are presented as median (lower quartile, upper quartile) or % (counts)
  2. * GCS = Glasgow Coma Scale; † IVH = intraventricular hemorrhage, ‡ EVD = external ventricular drainage; § NA = not available; ICH Score according to Hemphill [15]; ICH Grading Scale according to Ruiz-Sandoval [16]