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  1. Case report

    Conjugal amyotrophic lateral sclerosis: a case report from Scotland

    Conjugal amyotrophic lateral sclerosis is rare, with significant effects on psychological and care needs. We report a case of conjugal amyotrophic lateral sclerosis disease from central Scotland. This case is ...

    P. M. Fernandes, M. R. Macleod, A. Bateman, S. Abrahams and S. Pal

    BMC Neurology 2017 17:64

    Published on: 29 March 2017

  2. Research article

    Healthcare resource use and costs of multiple sclerosis patients in Germany before and during fampridine treatment

    Multiple sclerosis (MS) patients often suffer from gait impairment and fampridine is indicated to medically improve walking ability in this population. Patient characteristics, healthcare resource use, and cos...

    Tjalf Ziemssen, Christine Prosser, Jennifer Scarlet Haas, Andrew Lee, Sebastian Braun, Pamela Landsman-Blumberg, Angela Kempel, Erika Gleißner, Sarita Patel and Ming-Yi Huang

    BMC Neurology 2017 17:62

    Published on: 27 March 2017

  3. Study protocol

    Protocol for a randomized, double blind, placebo controlled, crossover trial of Melatonin for treatment of Nocturia in adults with Multiple Sclerosis (MeNiMS)

    Nocturia (the symptom of needing to wake up to pass urine) is common in progressive Multiple Sclerosis (MS) patients. Moderate-to-severe nocturia affects quality of life, can exacerbate fatigue and may affect ...

    D. Delgado, L. Canham, N. Cotterill, D. Cottrell, M. J. Drake, K. Inglis, D. Owen and P. White

    BMC Neurology 2017 17:63

    Published on: 27 March 2017

  4. Research article

    Cigarette smoking is an independent risk factor for post-stroke delirium

    Post-stroke delirium is a common problem in the care of stroke patients, and is associated with longer hospitalization, high short-term mortality, and an increased need for long-term care. Although post-stroke...

    Tae Sung Lim, Jin Soo Lee, Jung Han Yoon, So Young Moon, In Soo Joo, Kyoon Huh and Ji Man Hong

    BMC Neurology 2017 17:56

    Published on: 23 March 2017

  5. Research article

    Health care cost associated with the use of enzyme-inducing and non-enzyme–active antiepileptic drugs in the UK: a long-term retrospective matched cohort study

    Some antiepileptic drugs (AEDs) induce expression of hepatic enzymes. This can contribute to comorbidities via interference with metabolic pathways and concomitant drug metabolization, thereby increasing the l...

    Simon Borghs, Solène Thieffry, Matthias Noack-Rink, Peter Dedeken, Lai San Hong, Laura Byram, John Logan, Jane Chan and Victor Kiri

    BMC Neurology 2017 17:59

    Published on: 23 March 2017

  6. Research article

    Ipsilateral and contralateral sensory changes in healthy subjects after experimentally induced concomitant sensitization and hypoesthesia

    In unilateral neuropathic pain. e.g. after peripheral nerve injury, both positive and negative sensory signs occur often, accompanied by minor but equally directed contralateral sensory changes. To mimic this ...

    Elena K. Enax-Krumova, Stephanie Pohl, Andrea Westermann and Christoph Maier

    BMC Neurology 2017 17:60

    Published on: 23 March 2017

  7. Technical advance

    Process for developing rehabilitation practice recommendations for individuals with traumatic brain injury

    Attempts at measuring quality of rehabilitation care are hampered by a gap in knowledge translation of evidence-based approaches and lack of consensus on best practices. However, adoption of evidence-based bes...

    Librada Callender, Rachel Brown, Simon Driver, Marie Dahdah, Ashley Collinsworth and Shahid Shafi

    BMC Neurology 2017 17:54

    Published on: 20 March 2017

  8. Research article

    Outcome of neurological early rehabilitation patients carrying multi-drug resistant bacteria: results from a German multi-center study

    Colonization or infection with multi-drug resistant (MDR) bacteria is considered detrimental to the outcome of neurological and neurosurgical early rehabilitation patients.

    J. D. Rollnik, M. Bertram, C. Bucka, M. Hartwich, M. Jöbges, G. Ketter, B. Leineweber, M. Mertl-Rötzer, D. A. Nowak, T. Platz, K. Scheidtmann, R. Thomas, F. von Rosen, C. W. Wallesch, H. Woldag, P. Peschel…

    BMC Neurology 2017 17:53

    Published on: 20 March 2017

  9. Research article

    Mindfulness-based interventions in epilepsy: a systematic review

    Mindfulness based interventions (MBIs) are increasingly used to help patients cope with physical and mental long-term conditions (LTCs). Epilepsy is associated with a range of mental and physical comorbidities...

    Karen Wood, Maggie Lawrence, Bhautesh Jani, Robert Simpson and Stewart W. Mercer

    BMC Neurology 2017 17:52

    Published on: 20 March 2017

  10. Research article

    Leukoaraiosis is associated with pneumonia after acute ischemic stroke

    Stroke-associated pneumonia (SAP) is common in patients with acute ischemic stroke, and several risk factors have been reported. However, the relationship between underlying leukoaraiosis (LA) and SAP has not ...

    Ki-Woong Nam, Hyung-Min Kwon, Jae-Sung Lim and Yong-Seok Lee

    BMC Neurology 2017 17:51

    Published on: 16 March 2017

  11. Research article

    Stroke unit care in germany: the german stroke registers study group (ADSR)

    Factors influencing access to stroke unit (SU) care and data on quality of SU care in Germany are scarce. We investigated characteristics of patients directly admitted to a SU as well as patient-related and st...

    Steffi Hillmann, Silke Wiedmann, Viktoria Rücker, Klaus Berger, Darius Nabavi, Ingo Bruder, Hans-Christian Koennecke, Günter Seidel, Björn Misselwitz, Alfred Janssen, Christoph Burmeister, Christine Matthis, Otto Busse, Peter Hermanek and Peter Ulrich Heuschmann

    BMC Neurology 2017 17:49

    Published on: 9 March 2017

  12. Research article

    Measurement properties of painDETECT: Rasch analysis of responses from community-dwelling adults with neuropathic pain

    painDETECT (PD-Q) is a self-reported assessment of pain qualities developed as a screening tool for pain of neuropathic origin. Rasch analysis is a strategy for examining the measurement characteristics of a s...

    Tara L. Packham, Joseph C. Cappelleri, Alesia Sadosky, Joy C. MacDermid and Florian Brunner

    BMC Neurology 2017 17:48

    Published on: 4 March 2017

  13. Case report

    Rapidly progressive psychotic symptoms triggered by infection in a patient with methylenetetrahydrofolate reductase deficiency: a case report

    Methylenetetrahydrofolate reductase (MTHFR) deficiency is a rare inborn error of metabolism inherited in autosomal recessive pattern and is associated with a wide spectrum of neurological abnormalities.

    Shin Iida, Masataka Nakamura, Shinya Asayama, Takenobu Kunieda, Satoshi Kaneko, Hitoshi Osaka and Hirofumi Kusaka

    BMC Neurology 2017 17:47

    Published on: 28 February 2017

  14. Research article

    Development and validation of a score for evaluating comprehensive stroke care capabilities: J-ASPECT Study

    Although the Brain Attack Coalition recommended establishing centers of comprehensive care for stroke and cerebrovascular disease patients, a scoring system for such centers was lacking. We created and validat...

    Akiko Kada, Kunihiro Nishimura, Jyoji Nakagawara, Kuniaki Ogasawara, Junichi Ono, Yoshiaki Shiokawa, Toru Aruga, Shigeru Miyachi, Izumi Nagata, Kazunori Toyoda, Shinya Matsuda, Akifumi Suzuki, Hiroharu Kataoka, Fumiaki Nakamura, Satoru Kamitani and Koji Iihara

    BMC Neurology 2017 17:46

    Published on: 28 February 2017

  15. Research article

    Syncope and Epilepsy coexist in ‘possible’ and ‘drug-resistant’ epilepsy (Overlap between Epilepsy and Syncope Study - OESYS)

    Differential diagnosis between syncope and epilepsy in patients with transient loss of consciousness of uncertain etiology is still unclear. Thus, the aim of the present work is to evaluate the prevalence of s...

    Andrea Ungar, Alice Ceccofiglio, Francesca Pescini, Chiara Mussi, Gianni Tava, Martina Rafanelli, Assunta Langellotto, Niccolò Marchionni, J. Gert van Dijk, Gianlugi Galizia, Domenico Bonaduce and Pasquale Abete

    BMC Neurology 2017 17:45

    Published on: 28 February 2017

  16. Research article

    What is the optimal sequence of decompression for multilevel noncontinuous spinal cord compression injuries in rabbits?

    In recent years, multilevel spinal cord injuries (SCIs) have gained a substantial amount of attention from clinicians and researchers. Multilevel noncontinuous SCI patients cannot undergo the multiple steps of...

    Chaohua Yang, Baoqing Yu, Fenfen Ma, Huiping Lu, Jianmin Huang, Qinghua You, Bin Yu, Jianlan Qiao and Jianjun Feng

    BMC Neurology 2017 17:44

    Published on: 23 February 2017

  17. Study protocol

    Assessment and rehabilitation of central sensory impairments for balance in mTBI using auditory biofeedback: a randomized clinical trial

    Complaints of imbalance are common non-resolving signs in individuals with post-concussive syndrome. Yet, there is no consensus rehabilitation for non-resolving balance complaints following mild traumatic brai...

    Peter C. Fino, Robert J. Peterka, Timothy E. Hullar, Chad Murchison, Fay B. Horak, James C. Chesnutt and Laurie A. King

    BMC Neurology 2017 17:41

    Published on: 23 February 2017

  18. Research article

    Anxiety, emotional processing and depression in people with multiple sclerosis

    Despite the high comorbidity of anxiety and depression in people with multiple sclerosis (MS), little is known about their inter-relationships. Both involve emotional perturbations and the way in which emotion...

    Marie-Claire Gay, Catherine Bungener, Sarah Thomas, Pierre Vrignaud, Peter W Thomas, Roger Baker, Sébastien Montel, Olivier Heinzlef, Caroline Papeix, Rana Assouad and Michèle Montreuil

    BMC Neurology 2017 17:43

    Published on: 23 February 2017

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