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  1. Case report

    Stroke caused by an inflammatory thrombus: a case report

    Stroke is the leading cause of mortality and disability worldwide. Several definite risk factors have been identified for stroke, although infectious factors might also contribute to stroke episodes through in...

    Kai Shan and Wei Guo

    BMC Neurology 2017 17:33

    Published on: 16 February 2017

  2. Research article

    Relationship between ABCB1 3435TT genotype and antiepileptic drugs resistance in Epilepsy: updated systematic review and meta-analysis

    Antiepileptic drugs (AEDs) are effective medications available for epilepsy. However, many patients do not respond to this treatment and become resistant. Genetic polymorphisms may be involved in the variation...

    Malek Chouchi, Wajih Kaabachi, Hedia Klaa, Kalthoum Tizaoui, Ilhem Ben-Youssef Turki and Lamia Hila

    BMC Neurology 2017 17:32

    Published on: 15 February 2017

  3. Research article

    Long noncoding RNA papillary thyroid carcinoma susceptibility candidate 3 (PTCSC3) inhibits proliferation and invasion of glioma cells by suppressing the Wnt/β-catenin signaling pathway

    The dysregulation of long noncoding RNAs (lncRNAs) has been identified in a variety of cancers. An increasing number of studies have found the critical role of lncRNAs in the regulation of cellular processes, ...

    Shujun Xia, Ri Ji and Weiwei Zhan

    BMC Neurology 2017 17:30

    Published on: 10 February 2017

  4. Case report

    Case report: subacute tetraplegia in an immunocompromised patient

    Clinical reasoning in Neurology is based on general associations which help to deduce the site of the lesion. However, even “golden principles” may occasionally be deceptive. Here, we describe the case of suba...

    Daniel Zeller, Anke Heidemeier, Götz Ulrich Grigoleit and Wolfgang Müllges

    BMC Neurology 2017 17:31

    Published on: 10 February 2017

  5. Research article

    Peginterferon beta-1a improves MRI measures and increases the proportion of patients with no evidence of disease activity in relapsing-remitting multiple sclerosis: 2-year results from the ADVANCE randomized controlled trial

    Subcutaneous peginterferon beta-1a has previously been shown to reduce the number of T2-hyperintense and gadolinium-enhancing (Gd+) lesions over 2 years in patients with relapsing-remitting multiple sclerosis ...

    Douglas L. Arnold, Peter A. Calabresi, Bernd C. Kieseier, Shifang Liu, Xiaojun You, Damian Fiore and Serena Hung

    BMC Neurology 2017 17:29

    Published on: 10 February 2017

  6. Research article

    Non-neuronal cholinergic activity is potentiated in myasthenia gravis

    Non–neuronal acetylcholine (ACh) restricts autoimmune responses and attenuates inflammation by cholinergic anti-inflammation pathway. To date, the implication of ACh in myasthenia gravis (MG) remained unexplor...

    Bin Han, Chao Zhang, Shoufeng Liu, Yiping Xia, Hao Sun, Zhongying Gong, Alain R. Simard, Qiang Liu and Junwei Hao

    BMC Neurology 2017 17:28

    Published on: 8 February 2017

  7. Study protocol

    Evaluation and implementation of highly challenging balance training in clinical practice for people with Parkinson’s disease: protocol for the HiBalance effectiveness-implementation trial

    If people with progressive neurological diseases are to avail of evidence-based rehabilitation, programs found effective in randomized controlled trials (RCT’s) must firstly be adapted and tested in clinical e...

    Breiffni Leavy, Lydia Kwak, Maria Hagströmer and Erika Franzén

    BMC Neurology 2017 17:27

    Published on: 7 February 2017

  8. Research article

    A comparison of central nervous system involvement in patients with classical Fabry disease or the later-onset subtype with the IVS4+919G>A mutation

    Patients with the later-onset IVS4+919G>A (IVS4) Fabry mutation are known to have positive central nervous system involvement compared with age- and sex-matched controls. This study compares central nervous sy...

    Han-Jui Lee, Ting-Rong Hsu, Sheng-Che Hung, Wen-Chung Yu, Tzu-Hung Chu, Chia-Feng Yang, Svetlana Bizjajeva, Chui-Mei Tiu and Dau-Ming Niu

    BMC Neurology 2017 17:25

    Published on: 6 February 2017

  9. Study protocol

    Randomized controlled trial of a coordinated care intervention to improve risk factor control after stroke or transient ischemic attack in the safety net: Secondary stroke prevention by Uniting Community and Chronic care model teams Early to End Disparities (SUCCEED)

    Recurrent strokes are preventable through awareness and control of risk factors such as hypertension, and through lifestyle changes such as healthier diets, greater physical activity, and smoking cessation. Ho...

    Amytis Towfighi, Eric M. Cheng, Monica Ayala-Rivera, Heather McCreath, Nerses Sanossian, Tara Dutta, Bijal Mehta, Robert Bryg, Neal Rao, Shlee Song, Ali Razmara, Magaly Ramirez, Theresa Sivers-Teixeira, Jamie Tran, Elizabeth Mojarro-Huang, Ana Montoya…

    BMC Neurology 2017 17:24

    Published on: 6 February 2017

  10. Case report

    Kikuchi-Fujimoto disease (histiocytic necrotizing lymphadenitis) with atypical encephalitis and painful testitis: a case report

    Kikuchi-Fujimoto disease is a self-limited clinicopathologic entity that is increasingly recognized worldwide. Kikuchi-Fujimoto disease is characterized by cervical lymphadenopathy occurring in young adults. N...

    Hidenori Kido, Osamu Kano, Asami Hamai, Hiroyuki Masuda, Yutaka Fuchinoue, Masaaki Nemoto, Chiaki Arai, Teppei Takeda, Fumihito Yamabe, Toshihiro Tai, Mizuki Kasahara, Kenichi Suzuki, Nobuyuki Shiraga, Sota Sadamoto, Megumi Wakayama, Yukitoshi Takahashi…

    BMC Neurology 2017 17:22

    Published on: 1 February 2017

  11. Research article

    Lower serum uric acid level strongly predict short-term poor functional outcome in acute stroke with normoglycaemia: a cohort study in China

    Conflicting results on the correlation between hyperuricemia and the prognosis of stroke had been reported and the close association between serum uric acid (SUA) and abnormal glycomatabolism might further com...

    Shuolin Wu, Yuesong Pan, Ning Zhang, Wang Yong Jun and Chunxue Wang

    BMC Neurology 2017 17:21

    Published on: 1 February 2017

  12. Research article

    Functional outcome and complications after the microsurgical removal of giant vestibular schwannomas via the retrosigmoid approach: a retrospective review of 16-year experience in a single hospital

    Intracranial vestibular schwannoma still remain to be difficulty for its unique microsurgical technique and preservation of neuro-function, as well as reducing common complications that may arise in surgery.

    Xiang Huang, Jian Xu, Ming Xu, Mingyu Chen, Kaiyuan Ji, Junwei Ren and Ping Zhong

    BMC Neurology 2017 17:18

    Published on: 31 January 2017

  13. Research article

    Elevated blood viscosity is associated with cerebral small vessel disease in patients with acute ischemic stroke

    Increased level of blood viscosity, which is one of the major factors that determine blood rheology, has been reported as a risk factor or predictor for cerebrovascular events. We investigated how blood viscos...

    Seung Hoon Song, Jeong Hee Kim, Joon Hwa Lee, Yeo-Min Yun, Dong-Hee Choi and Hahn Young Kim

    BMC Neurology 2017 17:20

    Published on: 31 January 2017

  14. Research article

    Monitoring training activity during gait-related balance exercise in individuals with Parkinson’s disease: a proof-of-concept-study

    Despite the benefits of balance exercise in clinical populations, balance training programs tend to be poorly described, which in turn makes it difficult to evaluate important training components and compare b...

    David Conradsson, Håkan Nero, Niklas Löfgren, Maria Hagströmer and Erika Franzén

    BMC Neurology 2017 17:19

    Published on: 31 January 2017

  15. Research article

    Long-term efficacy and safety of fingolimod in Japanese patients with relapsing multiple sclerosis: 3-year results of the phase 2 extension study

    The low level of disease activity and manageable safety profile seen with fingolimod versus placebo in a 6-month, phase 2, randomized controlled trial in Japanese patients with relapsing multiple sclerosis (MS...

    Takahiko Saida, Yasuto Itoyama, Seiji Kikuchi, Qi Hao, Takayoshi Kurosawa, Kengo Ueda, Lixin Zhang Auberson, Isao Tsumiyama, Kazuo Nagato and Jun-ichi Kira

    BMC Neurology 2017 17:17

    Published on: 28 January 2017

  16. Case report

    Dancing with a seizure, a case report

    Dancing is a very rare seizure semiology, and has only few case reports so far. Moreover, no case regarded as dancing with both description and video was presented.

    Keun Tae Kim, Kon Chu and Sang Kun Lee

    BMC Neurology 2017 17:16

    Published on: 25 January 2017

  17. Research article

    Why use a mirror to assess visual pursuit in prolonged disorders of consciousness? Evidence from healthy control participants

    Evidence of reliable smooth visual pursuit is crucial for both diagnosis and prognosis in prolonged disorders of consciousness (PDOC). However, a mirror is more likely than an object to elicit evidence of smoo...

    Damian Cruse, Marco Fattizzo, Adrian M. Owen and Davinia Fernández-Espejo

    BMC Neurology 2017 17:14

    Published on: 24 January 2017

  18. Case report

    LETM presented with causalgia and ensued by sudden death

    Longitudinally Extensive Transverse Myelitis LETM is a specific pattern of myelitis wherein at least three continuous vertebral segments are involved. Characteristically, it is a defining feature of neuromyeli...

    Rana Alnasser Alsukhni, Yasmin Aboras, Ziena Jriekh, Mahmoud Almalla and Ahmad Sheikh El-Kahwateya

    BMC Neurology 2017 17:13

    Published on: 21 January 2017

  19. Research article

    Electrocardiographic assessments and cardiac events after fingolimod first dose – a comprehensive monitoring study

    First dose observation for cardiac effects is required for fingolimod, but recommendations on the extent vary. This study aims to assess cardiac safety of fingolimod first dose. Individual bradyarrhythmic epis...

    Volker Limmroth, Tjalf Ziemssen, Michael Lang, Stephan Richter, Bert Wagner, Judith Haas, Stephan Schmidt, Kathrin Gerbershagen, Christoph Lassek, Luisa Klotz, Olaf Hoffmann, Christian Albert, Katrin Schuh, Monika Baier-Ebert, Guillaume Wendt, Heinke Schieb…

    BMC Neurology 2017 17:11

    Published on: 18 January 2017

  20. Research article

    Subjective and objective assessment of physical activity in multiple sclerosis and their relation to health-related quality of life

    Physical activity (PA) is frequently restricted in people with multiple sclerosis (PwMS) and aiming to enhance PA is considered beneficial in this population. We here aimed to explore two standard methods (sub...

    Theresa Krüger, Janina R. Behrens, Anuschka Grobelny, Karen Otte, Sebastian Mansow-Model, Bastian Kayser, Judith Bellmann-Strobl, Alexander U. Brandt, Friedemann Paul and Tanja Schmitz-Hübsch

    BMC Neurology 2017 17:10

    Published on: 13 January 2017

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