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  1. Research article

    Biochemical markers in vascular cognitive impairment associated with subcortical small vessel disease - A consensus report

    Vascular cognitive impairment (VCI) is a heterogeneous entity with multiple aetiologies, all linked to underlying vascular disease. Among these, VCI related to subcortical small vessel disease (SSVD) is emergi...

    A. Wallin, E. Kapaki, M. Boban, S. Engelborghs, D. M. Hermann, B. Huisa, M. Jonsson, M. G. Kramberger, L. Lossi, B. Malojcic, S. Mehrabian, A. Merighi, E. B. Mukaetova-Ladinska, G. P. Paraskevas, B. O. Popescu, R. Ravid…

    BMC Neurology 2017 17:102

    Published on: 23 May 2017

  2. Research article

    Association of fibrinogen level with early neurological deterioration among acute ischemic stroke patients with diabetes

    Diabetes mellitus (DM) is a risk factor for early neurological deterioration (END) in acute ischemic stroke. The prothrombotic protein fibrinogen is frequently elevated in patients with diabetes, and may be as...

    Seong-Joon Lee, Ji Man Hong, Sung Eun Lee, Dae Ryong Kang, Bruce Ovbiagele, Andrew M. Demchuk and Jin Soo Lee

    BMC Neurology 2017 17:101

    Published on: 19 May 2017

  3. Study protocol

    The intracerebral hemorrhage acutely decreasing arterial pressure trial II (ICH ADAPT II) protocol

    Aggressively lowering blood pressure (BP) in acute intracerebral hemorrhage (ICH) may improve outcome. Although there is no evidence that BP reduction changes cerebral blood flow, retrospective magnetic resona...

    Laura Gioia, Ana Klahr, Mahesh Kate, Brian Buck, Dariush Dowlatshahi, Thomas Jeerakathil, Derek Emery and Kenneth Butcher

    BMC Neurology 2017 17:100

    Published on: 19 May 2017

  4. Research article

    The association between lunar phase and intracranial aneurysm rupture: Myth or reality? Own data and systematic review

    It is a common belief in medical community that lunar phases have an impact on human health. A growing body of evidence indicates that lunar phases can predict the risk to develop acute neurological and vascul...

    Adomas Bunevicius, Agne Gendvilaite, Vytenis Pranas Deltuva and Arimantas Tamasauskas

    BMC Neurology 2017 17:99

    Published on: 19 May 2017

  5. Research article

    Clinical experience with transcutaneous supraorbital nerve stimulation in patients with refractory migraine or with migraine and intolerance to topiramate: a prospective exploratory clinical study

    Migraine is included in the top-ten disabling diseases and conditions among the Western populations. Non-invasive neurostimulation, including the Cefaly® device, for the treatment of various types of pain is a...

    Michail Vikelis, Emmanouil V. Dermitzakis, Konstantinos C. Spingos, Georgios G. Vasiliadis, George S. Vlachos and Evaggelia Kararizou

    BMC Neurology 2017 17:97

    Published on: 18 May 2017

  6. Case report

    Case report: a novel frameshift mutation in the mitochondrial cytochrome c oxidase II gene causing mitochondrial disorder

    Mitochondrial cytochrome c oxidase 2, MT-CO2, encodes one of the three subunits, which form the catalytic core of cytochrome c oxidase (COX), complex IV. Mutations in MT-CO2 are rare a...

    Laura Kytövuori, Mikko Kärppä, Hannu Tuominen, Johanna Uusimaa, Markku Saari, Reetta Hinttala and Kari Majamaa

    BMC Neurology 2017 17:96

    Published on: 18 May 2017

  7. Research article

    Sex differences underlying orofacial varicella zoster associated pain in rats

    Most people are initially infected with varicella zoster virus (VZV) at a young age and this infection results in chickenpox. VZV then becomes latent and reactivates later in life resulting in herpes zoster (H...

    Crystal Stinson, Mohong Deng, Michael B Yee, Larry L. Bellinger, Paul R. Kinchington and Phillip R. Kramer

    BMC Neurology 2017 17:95

    Published on: 17 May 2017

  8. Research article

    Voxel-wise correlations between cognition and cerebral blood flow using arterial spin-labeled perfusion MRI in patients with Alzheimer’s disease: a cross-sectional study

    To analyze voxel-wise correlation between cerebral blood flow (CBF) measured using ASL-MRI and cognition in patients with Alzheimer’s disease (AD).

    Tomohiro Kaneta, Omi Katsuse, Takamasa Hirano, Matsuyoshi Ogawa, Ayako Shihikura-Hino, Keisuke Yoshida, Toshinari Odawara, Yoshio Hirayasu and Tomio Inoue

    BMC Neurology 2017 17:91

    Published on: 15 May 2017

  9. Case report

    A possible role of low regulatory T cells in anti-acetylcholine receptor antibody positive myasthenia gravis after bone marrow transplantation

    Chronic graft-versus-host disease (GVHD) appears several months following allogenic hematopoietic stem cell transplantation (HSCT) and is clinically analogous to autoimmune disorder. Polymyositis is a common n...

    Masahiko Fukatsu, Takenobu Murakami, Hiroshi Ohkawara, Shunichi Saito, Kazuhiko Ikeda, Suguru Kadowaki, Itaru Sasaki, Mari Segawa, Tomoko Soeda, Akihiko Hoshi, Hiroshi Takahashi, Akiko Shichishima-Nakamura, Kazuei Ogawa, Yoshihiro Sugiura, Hitoshi Ohto, Yasuchika Takeishi…

    BMC Neurology 2017 17:93

    Published on: 15 May 2017

  10. Research article

    Transcranial doppler sonography is not a valid diagnostic tool for detection of basilar artery stenosis or in-stent restenosis: a retrospective diagnostic study

    There are contradictory reports concerning the validity of transcranial sonography (TCD and TCCS) for examinations of the basilar artery. Here we investigated sensitivity and specificity of transcranial sonogr...

    Woori Koh, Kai Kallenberg, André Karch, Tobias Frank, Michael Knauth, Mathias Bähr and Jan Liman

    BMC Neurology 2017 17:89

    Published on: 11 May 2017

  11. Research article

    A diagnostic biomarker profile for fibromyalgia syndrome based on an NMR metabolomics study of selected patients and controls

    Fibromyalgia syndrome (FMS) is a chronic pain syndrome. A plausible pathogenesis of the disease is uncertain and the pursuit of measurable biomarkers for objective identification of affected individuals is a c...

    Bontle G. Malatji, Helgard Meyer, Shayne Mason, Udo F.H. Engelke, Ron A. Wevers, Mari van Reenen and Carolus J. Reinecke

    BMC Neurology 2017 17:88

    Published on: 11 May 2017

  12. Research article

    The effects of video game therapy on balance and attention in chronic ambulatory traumatic brain injury: an exploratory study

    Patients with traumatic brain injury often have balance and attentive disorders. Video game therapy (VGT) has been proposed as a new intervention to improve mobility and attention through a reward-learning app...

    Sofia Straudi, Giacomo Severini, Amira Sabbagh Charabati, Claudia Pavarelli, Giulia Gamberini, Anna Scotti and Nino Basaglia

    BMC Neurology 2017 17:86

    Published on: 10 May 2017

  13. Research article

    Effect of tendon vibration during wide-pulse neuromuscular electrical stimulation (NMES) on the decline and recovery of muscle force

    Neuromuscular electrical stimulation (NMES) is commonly used to activate skeletal muscles and reverse muscle atrophy in clinical populations. Clinical recommendations for NMES suggest the use of short pulse wi...

    Vanesa Bochkezanian, Robert U. Newton, Gabriel S. Trajano, Amilton Vieira, Timothy S. Pulverenti and Anthony J. Blazevich

    BMC Neurology 2017 17:82

    Published on: 2 May 2017

  14. Research article

    Effectiveness of the capsaicin 8% patch in the management of peripheral neuropathic pain in European clinical practice: the ASCEND study

    In randomised studies, the capsaicin 8% patch has demonstrated effective pain relief in patients with peripheral neuropathic pain (PNP) arising from different aetiologies.

    Colette Mankowski, Chris D. Poole, Etienne Ernault, Roger Thomas, Ellen Berni, Craig J. Currie, Cecil Treadwell, José I. Calvo, Christina Plastira, Eirini Zafeiropoulou and Isaac Odeyemi

    BMC Neurology 2017 17:80

    Published on: 21 April 2017

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