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  1. Research article

    Effectiveness of the capsaicin 8% patch in the management of peripheral neuropathic pain in European clinical practice: the ASCEND study

    In randomised studies, the capsaicin 8% patch has demonstrated effective pain relief in patients with peripheral neuropathic pain (PNP) arising from different aetiologies.

    Colette Mankowski, Chris D. Poole, Etienne Ernault, Roger Thomas, Ellen Berni, Craig J. Currie, Cecil Treadwell, José I. Calvo, Christina Plastira, Eirini Zafeiropoulou and Isaac Odeyemi

    BMC Neurology 2017 17:80

    Published on: 21 April 2017

  2. Case report

    Cortical laminar necrosis in dengue encephalitis—a case report

    Dengue encephalitis is a rare neurological manifestation of dengue fever. Its clinical presentation is similar to other viral encephalitides and encephalopathy. No single specific finding on magnetic resonance...

    Ravindra Kumar Garg, Imran Rizvi, Rajan Ingole, Amita Jain, Hardeep Singh Malhotra, Neeraj Kumar and Dhruv Batra

    BMC Neurology 2017 17:79

    Published on: 20 April 2017

  3. Case report

    Anti-MOG antibody-positive ADEM following infectious mononucleosis due to a primary EBV infection: a case report

    Anti-Myelin oligodendrocyte glycoprotein (MOG) antibodies are detected in various demyelinating diseases, such as pediatric acute disseminated encephalomyelitis (ADEM), recurrent optic neuritis, and aquaporin-...

    Yoshitsugu Nakamura, Hideto Nakajima, Hiroki Tani, Takafumi Hosokawa, Shimon Ishida, Fumiharu Kimura, Kimihiko Kaneko, Toshiyuki Takahashi and Ichiro Nakashima

    BMC Neurology 2017 17:76

    Published on: 19 April 2017

  4. Research article

    Clinical predictors for the prognosis of myasthenia gravis

    Clinical predictors for myasthenia gravis relapse and ocular myasthenia gravis secondary generalization during the first two years after disease onset remain incompletely identified. This study attempts to inv...

    Lili Wang, Yun Zhang and Maolin He

    BMC Neurology 2017 17:77

    Published on: 19 April 2017

  5. Case report

    An unusual delusion of duplication in a patient affected by Dementia with Lewy bodies

    Dementia with Lewy bodies (DLB) is the second most frequent diagnosis of progressive degenerative dementia in older people. Delusions are common features in DLB and, among them, Capgras syndrome represents the...

    Paolo Solla, Gioia Mura, Antonino Cannas, Gianluca Floris, Davide Fonti, Gianni Orofino, Mauro Giovanni Carta and Francesco Marrosu

    BMC Neurology 2017 17:78

    Published on: 19 April 2017

  6. Study protocol

    Study protocol: Insight 46 – a neuroscience sub-study of the MRC National Survey of Health and Development

    Increasing age is the biggest risk factor for dementia, of which Alzheimer’s disease is the commonest cause. The pathological changes underpinning Alzheimer’s disease are thought to develop at least a decade p...

    Christopher A. Lane, Thomas D. Parker, Dave M. Cash, Kirsty Macpherson, Elizabeth Donnachie, Heidi Murray-Smith, Anna Barnes, Suzie Barker, Daniel G. Beasley, Jose Bras, David Brown, Ninon Burgos, Michelle Byford, M. Jorge Cardoso, Ana Carvalho, Jessica Collins…

    BMC Neurology 2017 17:75

    Published on: 18 April 2017

  7. Technical advance

    A computerized tablet system for evaluating treatment of essential tremor by magnetic resonance guided focused ultrasound

    Transcranial magnetic resonance guided focused ultrasound is an emerging technology under evaluation for treatment of essential tremor, a prevalent movement disorder. A qualitative evaluation is performed by a...

    Fred Tam, Yuexi Huang, Michael L. Schwartz, Tom A. Schweizer, Kullervo Hynynen and Simon J. Graham

    BMC Neurology 2017 17:74

    Published on: 17 April 2017

  8. Commentary

    Big data and data repurposing - using existing data to answer new questions in vascular dementia research

    Traditional approaches to clinical research have, as yet, failed to provide effective treatments for vascular dementia (VaD). Novel approaches to collation and synthesis of data may allow for time and cost eff...

    Fergus N. Doubal, Myzoon Ali, G. David Batty, Andreas Charidimou, Maria Eriksdotter, Martin Hofmann-Apitius, Yun-Hee Kim, Deborah A. Levine, Gillian Mead, Hermann A. M. Mucke, Craig W. Ritchie, Charlotte J. Roberts, Tom C. Russ, Robert Stewart, William Whiteley and Terence J. Quinn

    BMC Neurology 2017 17:72

    Published on: 17 April 2017

  9. Research article

    Short-term motor learning through non-immersive virtual reality task in individuals with down syndrome

    Down syndrome (DS) has unique physical, motor and cognitive characteristics. Despite cognitive and motor difficulties, there is a possibility of intervention based on the knowledge of motor learning. However, ...

    Carlos Bandeira de Mello Monteiro, Talita Dias da Silva, Luiz Carlos de Abreu, Felipe Fregni, Luciano Vieira de Araujo, Fernando Henrique Inocêncio Borba Ferreira and Claudio Leone

    BMC Neurology 2017 17:71

    Published on: 14 April 2017

  10. Case report

    Double or nothing: red flag symptoms of critical carotid stenosis, a case report

    Detailed knowledge of every possible manifestation of Internal Carotid Artery (ICA) disease is important. For improving detection and a timely adoption of secondary prevention procedures or treatments. Transie...

    José Carlos Morán-Sánchez, Irene Gómez-Estévez, Yasmina El Berdei, José C. Gómez-Sánchez and María E. Ramos-Araque

    BMC Neurology 2017 17:69

    Published on: 5 April 2017

  11. Research article

    High dose vitamin D supplementation does not affect biochemical bone markers in multiple sclerosis – a randomized controlled trial

    People with multiple sclerosis have high risk of osteoporosis and fractures. A poor vitamin D status is a risk factor for MS, and vitamin D supplementation has been recommended both to prevent MS progression a...

    Trygve Holmøy, Jonas Christoffer Lindstrøm, Erik Fink Eriksen, Linn Hofsøy Steffensen and Margitta T. Kampman

    BMC Neurology 2017 17:67

    Published on: 4 April 2017

  12. Research article

    Bapineuzumab for mild to moderate Alzheimer’s disease: a meta-analysis of randomized controlled trials

    Alzheimer’s disease (AD) is a globally prevalent neurodegenerative condition, clinically characterized by progressive memory loss and gradual impairment of cognitive functions. Bapineuzumab is a fully humanize...

    Abdelrahman Ibrahim Abushouk, Ahmed Elmaraezy, Amro Aglan, Reham Salama, Samar Fouda, Rana Fouda and Ammar M. AlSafadi

    BMC Neurology 2017 17:66

    Published on: 4 April 2017

  13. Case report

    Conjugal amyotrophic lateral sclerosis: a case report from Scotland

    Conjugal amyotrophic lateral sclerosis is rare, with significant effects on psychological and care needs. We report a case of conjugal amyotrophic lateral sclerosis disease from central Scotland. This case is ...

    P. M. Fernandes, M. R. Macleod, A. Bateman, S. Abrahams and S. Pal

    BMC Neurology 2017 17:64

    Published on: 29 March 2017

  14. Research article

    Healthcare resource use and costs of multiple sclerosis patients in Germany before and during fampridine treatment

    Multiple sclerosis (MS) patients often suffer from gait impairment and fampridine is indicated to medically improve walking ability in this population. Patient characteristics, healthcare resource use, and cos...

    Tjalf Ziemssen, Christine Prosser, Jennifer Scarlet Haas, Andrew Lee, Sebastian Braun, Pamela Landsman-Blumberg, Angela Kempel, Erika Gleißner, Sarita Patel and Ming-Yi Huang

    BMC Neurology 2017 17:62

    Published on: 27 March 2017

  15. Study protocol

    Protocol for a randomized, double blind, placebo controlled, crossover trial of Melatonin for treatment of Nocturia in adults with Multiple Sclerosis (MeNiMS)

    Nocturia (the symptom of needing to wake up to pass urine) is common in progressive Multiple Sclerosis (MS) patients. Moderate-to-severe nocturia affects quality of life, can exacerbate fatigue and may affect ...

    D. Delgado, L. Canham, N. Cotterill, D. Cottrell, M. J. Drake, K. Inglis, D. Owen and P. White

    BMC Neurology 2017 17:63

    Published on: 27 March 2017

  16. Research article

    Cigarette smoking is an independent risk factor for post-stroke delirium

    Post-stroke delirium is a common problem in the care of stroke patients, and is associated with longer hospitalization, high short-term mortality, and an increased need for long-term care. Although post-stroke...

    Tae Sung Lim, Jin Soo Lee, Jung Han Yoon, So Young Moon, In Soo Joo, Kyoon Huh and Ji Man Hong

    BMC Neurology 2017 17:56

    Published on: 23 March 2017

  17. Research article

    Health care cost associated with the use of enzyme-inducing and non-enzyme–active antiepileptic drugs in the UK: a long-term retrospective matched cohort study

    Some antiepileptic drugs (AEDs) induce expression of hepatic enzymes. This can contribute to comorbidities via interference with metabolic pathways and concomitant drug metabolization, thereby increasing the l...

    Simon Borghs, Solène Thieffry, Matthias Noack-Rink, Peter Dedeken, Lai San Hong, Laura Byram, John Logan, Jane Chan and Victor Kiri

    BMC Neurology 2017 17:59

    Published on: 23 March 2017

  18. Research article

    Ipsilateral and contralateral sensory changes in healthy subjects after experimentally induced concomitant sensitization and hypoesthesia

    In unilateral neuropathic pain. e.g. after peripheral nerve injury, both positive and negative sensory signs occur often, accompanied by minor but equally directed contralateral sensory changes. To mimic this ...

    Elena K. Enax-Krumova, Stephanie Pohl, Andrea Westermann and Christoph Maier

    BMC Neurology 2017 17:60

    Published on: 23 March 2017

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