Copeptin is associated with mortality and outcome in patients with acute intracerebral hemorrhage

BMC Neurology

Table 3 Prediction of adverse 90 days outcome defined as a Barthel score < 85 points and mRS < 3 (n = 22) in univariate analysis of all patients (n = 40)

Parameter*	Odds Ratio	95% CI		p
Age	1.09	1.01	1.16	*0.023*
Gender	2.40	0.66	8.72	0.184
GCS	0.42	0.19	0.94	*0.036*
Charlson Index	1.88	0.96	3.68	0.07
Body Temperature	0.54	0.21	1.39	0.20
Hematoma Volume	1.06	1.01	1.10	*0.017*
ICH Score	5.48	1.81	16.48	*0.002*
ICH Grading Scale	2.84	1.34	5.98	*0.006*
Sodium	1.29	0.99	1.68	0.062
Osmolarity	1.15	0.97	1.35	0.098
Glucose	0.99	0.66	1.51	0.98
CRP	1.04	0.98	1.10	0.188
WBC	1.03	0.86	1.24	0.73
Copeptin	3.10	1.02	9.39	*0.046*

* Note that the odds ratio corresponds to a unit increase in the explanatory variable; for copeptin this corresponds to an increase per unit of the log-transformation of copeptin (thus a log transformed increase of 1 corresponds to a copeptin increase of 10 pmol/l). ICH Score according to Hemphill [15]; ICH Grading Scale according to Ruiz-Sandoval [15].

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