Table 1 Baseline characteristics of included studies
From: Corticosteroid and antiviral therapy for Bell's palsy: A network meta-analysis
Author (Year) | N | Mean age | % Male Participants | Mean disease severity score | Type of treatment | Outcomes | FU time(month) | QA score | |
|---|---|---|---|---|---|---|---|---|---|
Intervention (dosage) | Control | ||||||||
Adour et al. (1996) [8] | 99 | 43 | 50 | 3 (FPRP) | Acyclovir 2,000 mg/day × 10 days Prednisolone 30 mg/kg/day × 5 days, 10 mg/day × next 5 days | Prednisolone with the same dosage | FPRI ≥ 8 | 4 | 7 |
De Diego et al. (1998)[25] | 101 | - | - | - | Acyclovir 2,400 mg/day ×10 days | Prednisolone 1 mg/kg/day × 10 days, taper over next 6 days | HB grade ≤ II, FPRI score≥ 8 | 3 | 3 |
Hato et al. (2007)[10] | 221 | 50 | 53 | 15 (Yanagihara) | Valacyclovir 1,000 mg/day × 5 days Prednisolone 60 mg/day for 5 days, taper with Mecobalamin 1·5 mg/day × 6 months | Placebo | Yanagihara score > 36 points, no facial contracture or synkinesis | 6 | 9 |
Sullivan et al. (2007) [12] | 551 | 44 | 51 | 3.6 (HB) | Acyclovir 2000 mg/day × 10 days Prednisolone 50 mg/day × 10 days | Placebo | HB grade I | 3, 9 | 12 |
Yeo et al. (2008)[13] | 91 | 41 | 45 | 3.7 (HB) | Acyclovir 2,400 mg/day × 5 days Prednisolone 1 mg/kg/day × 4 days with maximum of 80 mg/day, 60 mg/day × 5-6 day, 40 mg/day × 7-8 day, 20 mg/day × 9-10 day | Placebo | HB grade ≤ II | 2, 6 | 2 |
Engstrom et al. (2008) [9] | 829 | 40 | 59 | 4 by HB | Valacyclovir 3,000 mg/day × 7 days Prednisolone 60 mg/day × 5 days, 10 mg/day until 10 days | Placebo | Sunnybrook 100/100, HB ≤ II | 1, 2, 3, 6, 12 | 12 |