Table 2 Comparison of cryptococcal meningoencephalitis patients with and without acute/subacute cerebral infarction

Median age; range (years)

71 (46-78)

55 (19-82)

0.033 ^*

Male

4

21

0.659

Female

3

9

Underlying conditions

   Diabetes mellitus

3

2

0.037 ^*

   Liver disease

3

3

0.068

   Hypertension

1

6

1.000

Clinical manifestation

   Fever

5

15

0.113

   Altered consciousness

7

15

0.028 ^*

   Seizure

1

6

1.000

   Previous stroke

2

0

0.032 ^*

Hydrocephalus

4

11

0.408

Positive CSF India ink staining

0

10/27

0.145

Positive CSF culture

4

20/28

0.652

CSF data median (range)*

   WBC count (10 ⁹ /L)

144 (33-160)

136 (0-980)

0.575

   Glucose level (mmol/L)

26.5 (14-53)

24 (0-255)

0.827

   Glucose ratio

0.16 (0.07-0.31)

0.19 (0-0.96)

0.731

   Total protein level (g/L)

232.5 (113-431)

106 (55-1626)

0.131

   Lactate level (mmol/dL)

44.95 (31-67)

47.6 (9-97)

0.687

   Cryptococcus antigen

1:384 (1:4-1:1024)

1:1024 (1:4-1:4096)

0.265

Prognosis

   Poor

7

11

0.003