| Cohort 1 | Cohort 2 | |||||
---|---|---|---|---|---|---|---|
Domain | HC n = 295 | CFS * n = 145 | HC n = 19 | CFS ** n = 49 | CFS+MO** n = 28 | CFS+MA** n = 12 | CFS+T ** n = 9 |
Physical Functioning | 71.6 [67.8-75.4] | 47.6 [43.4-52.1] p < 10-10 | 91.1 [82.4-99.7] | 41.4 [34.6-48.2] p < 10-10 | 43.7 [35.5-51.9] p = 10-9 | 28.8 [15.6-41.9] p = 10-8 | 51.7 [34.5-68.8] p = 0.0001 |
Social Functioning | 67.4 [63.2-71.6] | 46.4 [41.8-51.0] p = 10-9 | 87.5 [76.5-98.5] | 26.9 [21.0-32.8] p < 10-10 | 25.5 [17.9-33.0] p < 10-10 | 23.9 [9.3-38.4] p = 10-7 | 35.9 [26.2-45.7] P = 0.000005 |
Role-Physical | 60.5 [63.2-71.6] | 18.5 [13.3-23.7] p < 10-10 | 76.3 [57.8-94.9] | 5.6 [0.8-10.4] p < 10-10 | 8.0 [0.5-15.6] p = 10-9 | 4.2 [-4.0-12.3] p = 10-6 | 0 P = 0.000009 |
Role-Emotional | 71.6 [62.8-80.3] | 53.3 [46.2-60.5] p = 0.008 | 86.0 [72.5-99.5] | 57.6 [44.8-70.5] | 59.3 [42.0-76.5] p = 0.03 | 55.6 [28.5-82.7] p = 0.04 | 55.6 [24.8-86.4] p = 0.048 |
Mental Health | 66.8 [63.0-70.5] | 58.4 [54.9-61.9] p = 0.006 | 79.2 [74.0-84.3] | 62.6 [57.0-68.3] | 64.9 [57.9-71.8] p = 0.005 | 59.7 [45.1-74.2] p = 0.007 | 59.6 [48.1-71.0] p = 0.001 |
Vitality | 50.1 [47.1-53.1] | 25.4 [22.3-28.5] p < 10-10 | 66.1 [56.5-75.8] | 13.9 [10.5-17.2] p < 10-10 | 14.8 [10.3-19.3] p < 10-10 | 6.7 [2.1-11.2] p = 10-10 | 20.6 [12.6-28.5] p = 10-6 |
Bodily Pain | 60.5 [56.5-64.6] | 35.1 [31.4-38.8] p < 10-10 | 83.8 [72.4-95.2] | 34.1 [28.1-40.2] p < 10-10 | 32.8 [25.3-40.3] p = 10-9 | 30.6 [16.2-44.9] p = 10-6 | 42.8 [29.5-56.0] p = 0.0003 |
General Health | 64.5 [56.5-64.6] | 38.3 [34.3-42.3] p < 10-10 | 76.8 [69.5-84.2] | 33.0 [27.8-38.2] p < 10-10 | 36.2 [28.3-44.1] p = 10-8 | 28.8 [19.9-37.6] p = 10-8 | 29.1 [20.9-37.4] p = 10-8 |