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Table 3 Amplitude and latency of ERP components for target and standard stimuli and for the CNV periods

From: Cluster analysis of behavioural and event-related potentials during a contingent negative variation paradigm in remitting-relapsing and benign forms of multiple sclerosis

   

Amplitude

    

Latency

  
  

Controls

RRMS

BMS

p

 

Controls

RRMS

BMS

p

ERPs

 

Mean ± SD

   

ERPs

Mean ± SD

   

(â—‹) eN1

    

0.001 a

     
 

Valid

-0.85 ± 2.4

0.47 ± 1.2

0.97 ± 1.2

      
 

Invalid

-0.63 ± 0.9

0.33 ± 1.5

0.96 ± 2.1

      

(â—‹) P1

    

0.020 a,b,c

(â—‹) P1

   

0.558

 

Valid

1.59 ± 1.8

1.86 ± 1.3

1.59 ± 1.0

  

132 ± 6

135 ± 6

136 ± 7

 
 

Invalid

1.17 ± 1.5

1.19 ± 1.2

2.09 ± 2.1

  

133 ± 7

133 ± 5

133 ± 6

 

(â—‹) N1

    

0.419

(â—‹) N1

   

< 0.001 a,c

 

Valid

- 0.95 ± 1.2

- 1.41 ± 1.1

- 1.01 ± 1.7

  

174 ± 11

179 ± 10

188 ± 8

 
 

Invalid

-0.98 ± 1.5

-1.46 ± 1.1

-0.81 ± 1.5

  

173 ± 11

181 ± 10

188 ± 9

 

(â—‹) P3

    

0.294

(â—‹) P3

   

0.003 a,b,c,d

 

Valid

4.99 ± 2.4

4.38 ± 4.8

4.56 ± 2.7

  

352 ± 1

371 ± 10

381 ± 18

 
 

Invalid

5.67 ± 1.4

5.18 ± 1.5

4.61 ± 2.5

  

353 ± 13

375 ± 17

390 ± 12

 

(⊙) P2

    

0.232

(⊙) P2

   

< 0.001 a

 

Valid

5.40 ± 2.8

5.37 ± 3.3

5.26 ± 3.7

  

219 ± 12

240 ± 13

241 ± 17

 
 

Invalid

5.99 ± 3.7

6.25 ± 2.7

7.25 ± 1.5

  

226 ± 11

242 ± 12

249 ± 13

 

(⊙) N2

    

0.169

(⊙) N2

   

0.002 a

 

Valid

-0.30 ± 1.7

-0.16 ± 1.8

-0.52 ± 3.8

  

252 ± 13

268 ± 10

271 ± 17

 
 

Invalid

-0.10 ± 2.6

-0.81 ± 2.4

-0.40 ± 3.1

  

262 ± 11

270 ± 12

269 ± 12

 

(⊙) P3

    

0.239

(⊙) P3

   

< 0.001 a

 

Valid

8.95 ± 3.7

7.63 ± 4.3

7.13 ± 4.4

  

372 ± 19

397 ± 15

399 ± 20

 
 

Invalid

9.81 ± 3.9

8.36 ± 4.1

9.22 ± 4.2

  

363 ± 20

381 ± 20

390 ± 17

 

(â—‹) LN

 

-1.72 ± 1.1

-1.80 ± 1.5

-1.68 ± 1.5

0.718

     

(⊙) LN

 

-2.23 ± 2.1

-3.24 ± 2.0

-1.13 ± 1.5

0.031 b

     

eCNV

 

-1.82 ± 1.7

-0.87 ± 1.1

-0.18 ± 2.2

0.035 a, c

     

cCNV

 

1.13 ± 0.8

-0.57 ± 0.8

0.89 ± 1.0

0.043 a, d

     

tCNV

 

0.57 ± 0.6

0.96 ± 0.7

0.74 ± 0.9

0.632

     
  1. Means and standard deviations (SD) of electrodes and regions of interest used for each ERP-component ANOVA analysis are shown. P values show main statistical effects involving the group factor.
  2. [⊙ = target stimuli; ○ = standard stimuli].
  3. a= p < 0.05 between control and both MS groups;
  4. b= p < 0.05 between RRMS and BMS groups;
  5. c= p = < 0.05 between control and BMS groups;
  6. d = p < 0.05 between control and RRMS groups.
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BMC Neurology

ISSN: 1471-2377

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