Cognitive performance in relapsing remitting multiple sclerosis: A longitudinal study in daily practice using a brief computerized cognitive battery

Table 4 Correlations between CDR measures and DSST, MSFC component scores and MSFC at baseline

	Power of Attention	Continuity of Attention	Quality of working memory	Quality of episodic memory	Speed of memory	CDR composite
DSST	0.61 p < 0.0001	0.49 p = 0.0009	0.33 p = 0.0333	0.25 p = 0.1068	0.55 p = 0.0001	0.7 p < 0.0001
Timed 25-FWT	0.18 p = 0.236	0.23 p = 0.1465	0.31 p = 0.0424	0.14 p = 0.3678	0.15 p = 0.3217	0.17 p = 0.2673
9-HPT	0.55 p = 0.0001	0.32 p = 0.0368	0.12 p = 0.3767	0.16 p = 0.3035	0.4 p = 0.0076	0.48 p = 0.001
PASAT 3"	0.6 p < 0.0001	0.31 p = 0.0431	0.2 p = 0.2092	0.17 p = 0.2692	0.35 p = 0.0209	0.49 p = 0.0009
MSFC	0.61 p = 0.0001	0.39 p = 0.0095	0.29 p = 0.0549	0.09 p = 0.5752	0.42 p = 0.0056	0.52 p = 0.0003

CDR, Cognitive Drug Research; DSST, Digit Symbol Substitution Test; MSFC, Multiple Sclerosis Functional Composite; Timed 25-FWT, Timed 25-Foot Walk Test; 9-HPT, 9 Hole Peg Test, PASAT 3", Paced Auditory Serial Addition Test 3 sec. Correcting for multiplicity p-values are statistically significant at p < 0.0017.

ISSN: 1471-2377