| PS-DHA | Placebo | |||||
---|---|---|---|---|---|---|---|
Variable | Baseline (mean ± SD) | 15 weeks (mean ± SD) | P value1 (within group) | Baseline (mean ± SD) | 15 weeks (mean ± SD) | P value1 (within group) | P value2 (between groups) |
White blood cell count (×103/cmm) | 6.8 ± 1.8 | 6.5 ± 1.6 | 0.083 | 7.1 ± 2.0 | 6.7 ± 1.9 | 0.011* | 0.434 |
Male | 6.8 ± 1.7 | 6.4 ± 1.5 | 0.020* | 7.3 ± 2.3 | 7.1 ± 2.2 | 0.298 | 0.467 |
Female | 6.7 ± 1.9 | 6.7 ± 1.6 | 0.829 | 6.9 ± 1.4 | 6.3 ± 1.3 | 0.009* | 0.066 |
Red blood cell count (×106/cmm) | 4.6 ± 0.5 | 4.6 ± 0.5 | 0.441 | 4.6 ± 0.4 | 4.6 ± 0.4 | 0.332 | 0.765 |
Male | 4.7 ± 0.5 | 4.7 ± 0.5 | 0.544 | 4.6 ± 0.4 | 4.6 ± 0.4 | 0.491 | 0.925 |
Female | 4.5 ± 0.4 | 4.4 ± 0.4 | 0.622 | 4.5 ± 0.4 | 4.5 ± 0.4 | 0.488 | 0.760 |
Hematocrit (%) | 41.2 ± 4.2 | 40.7 ± 4.3 | 0.113 | 41.6 ± 3.6 | 40.9 ± 3.6 | 0.045* | 0.504 |
Male | 42.5 ± 4.3 | 42.1 ± 4.4 | 0.229 | 42.6 ± 3.6 | 42.0 ± 3.4 | 0.100 | 0.763 |
Female | 39.8 ± 3.7 | 39.4 ± 3.8 | 0.309 | 40.5 ± 3.2 | 39.6 ± 3.5 | 0.193 | 0.548 |
Hemoglobin (g/dL) | 13.7 ± 1.5 | 13.7 ± 1.5 | 0.434 | 13.7 ± 1.2 | 13.6 ± 1.2 | 0.213 | 0.669 |
Male | 14.3 ± 1.4 | 14.3 ± 1.3 | 0.706 | 14.1 ± 1.2 | 13.9 ± 1.2 | 0.181 | 0.623 |
Female | 13.1 ± 1.4 | 13.0 ± 1.4 | 0.481 | 13.3 ± 1.1 | 13.2 ± 1.1 | 0.494 | 0.856 |
Platelet count (×103/cmm) | 221.5 ± 62.7 | 226.8 ± 60.5 | 0.374 | 226.9 ± 73.7 | 230.8 ± 68.8 | 0.347 | 0.839 |
Male | 200.1 ± 44.5 | 204.0 ± 44.3 | 0.479 | 202.8 ± 58.3 | 210.0 ± 61.1 | 0.128 | 0.648 |
Female | 243.5 ± 71.3 | 250.2 ± 66.4 | 0.536 | 255.4 ± 80.6 | 255.3 ± 70.4 | 0.980 | 0.592 |
Netrophils (%) | 62.8 ± 6.5 | 62.4 ± 6.4 | 0.514 | 63.8 ± 8.7 | 62.9 ± 8.6 | 0.207 | 0.543 |
Male | 65.1 ± 6.0 | 64.4 ± 5.7 | 0.390 | 64.8 ± 9.0 | 64.8 ± 9.2 | 0.968 | 0.569 |
Female | 60.4 ± 6.2 | 60.5 ± 6.7 | 0.969 | 62.6 ± 8.4 | 60.7 ± 7.5 | 0.097 | 0.147 |
Netrophils Absolute (×109/L) | 4.3 ± 1.3 | 4.1 ± 1.0 | 0.080 | 4.5 ± 1.4 | 4.2 ± 1.4 | 0.037* | 0.579 |
Male | 4.5 ± 1.3 | 4.1 ± 1.1 | 0.027* | 4.7 ± 1.5 | 4.6 ± 1.7 | 0.675 | 0.265 |
Female | 4.1 ± 1.2 | 4.0 ± 1.0 | 0.814 | 4.4 ± 1.2 | 3.8 ± 1.0 | 0.010* | 0.046* |
Lymphocytes (%) | 26.0 ± 6.1 | 26.1 ± 5.8 | 0.887 | 25.8 ± 8.7 | 26.4 ± 8.1 | 0.324 | 0.478 |
Male | 23.8 ± 5.6 | 24.4 ± 5.1 | 0.453 | 24.5 ± 8.8 | 24.4 ± 8.7 | 0.893 | 0.529 |
Female | 28.2 ± 5.8 | 27.8 ± 6.0 | 0.447 | 27.3 ± 8.4 | 28.8 ± 6.9 | 0.171 | 0.116 |
Lymphocytes Absolute (×109/L) | 1.8 ± 0.6 | 1.7 ± 0.5 | 0.167 | 1.9 ± 1.1 | 1.8 ± 0.8 | 0.051 | 0.449 |
Male | 1.6 ± 0.5 | 1.6 ± 0.4 | 0.234 | 1.9 ± 1.4 | 1.7 ± 1.0 | 0.115 | 0.468 |
Female | 1.9 ± 0.6 | 1.8 ± 0.6 | 0.458 | 1.8 ± 0.6 | 1.8 ± 0.5 | 0.238 | 0.819 |
Monocytes (%) | 5.8 ± 1.4 | 6.0 ± 1.5 | 0.119 | 5.6 ± 1.0 | 5.9 ± 1.4 | 0.093 | 0.918 |
Male | 5.9 ± 1.5 | 6.1 ± 1.4 | 0.343 | 5.7 ± 0.9 | 5.9 ± 1.3 | 0.299 | 0.976 |
Female | 5.6 ± 1.4 | 5.9 ± 1.6 | 0.220 | 5.5 ± 1.1 | 5.8 ± 1.5 | 0.193 | 0.895 |
Monocytes Absolute (×109/L) | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.731 | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.565 | 0.516 |
Male | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.497 | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.890 | 0.556 |
Female | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.284 | 0.4 ± 0.1 | 0.4 ± 0.1 | 0.359 | 0.159 |
Eosinophils (%) | 3.0 ± 2.5 | 3.1 ± 3.3 | 0.365 | 2.5 ± 1.6 | 2.5 ± 1.5 | 0.844 | 0.540 |
Male | 2.7 ± 1.5 | 2.8 ± 2.0 | 0.535 | 2.8 ± 1.8 | 2.7 ± 1.7 | 0.832 | 0.533 |
Female | 3.3 ± 3.3 | 3.5 ± 4.2 | 0.513 | 2.2 ± 1.4 | 2.3 ± 1.2 | 0.660 | 0.796 |
Eosinophils Absolute (×109/L) | 0.2 ± 0.3 | 0.2 ± 0.3 | 0.853 | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.227 | 0.400 |
Male | 0.2 ± 0.2 | 0.2 ± 0.2 | 0.421 | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.280 | 0.943 |
Female | 0.2 ± 0.4 | 0.3 ± 0.5 | 0.382 | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.513 | 0.284 |
Basophils (%) | 0.7 ± 0.3 | 0.6 ± 0.3 | 0.041* | 0.7 ± 0.3 | 0.6 ± 0.3 | 0.101 | 0.684 |
Male | 0.7 ± 0.3 | 0.6 ± 0.3 | 0.207 | 0.6 ± 0.3 | 0.6 ± 0.3 | 0.099 | 0.882 |
Female | 0.8 ± 0.2 | 0.6 ± 0.3 | 0.113 | 0.7 ± 0.4 | 0.7 ± 0.3 | 0.515 | 0.482 |
Basophils Absolute (×109/L) | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.006* | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.019* | 0.854 |
Male | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.035* | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.058 | 0.928 |
Female | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.077 | 0.1 ± 0.0 | 0.0 ± 0.0 | 0.174 | 0.701 |
Large Unstained Cells (%) | 1.7 ± 0.6 | 1.7 ± 0.5 | 1.000 | 1.6 ± 0.6 | 1.7 ± 0.6 | 0.162 | 0.306 |
Male | 1.8 ± 0.6 | 1.8 ± 0.5 | 0.616 | 1.6 ± 0.6 | 1.6 ± 0.6 | 0.623 | 0.483 |
Female | 1.7 ± 0.7 | 1.7. ± 0.6 | 0.701 | 1.7 ± 0.5 | 1.9 ± 0.6 | 0.139 | 0.434 |
Large Unstained Cells Absolute (×109/L) | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.652 | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.571 | 0.948 |
Male | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.243 | 0.1 ± 0.1 | 0.1 ± 0.1 | 0.568 | 0.753 |
Female | 0.1 ± 0.1 | 0.1 ± 0.0 | 0.784 | 0.1 ± 0.0 | 0.1 ± 0.0 | 0.847 | 0.742 |
MCV (μ3) | 90.1 ± 4.1 | 89.6 ± 4.4 | 0.133 | 91.0 ± 4.3 | 90.1 ± 4.3 | 0.049* | 0.506 |
Male | 90.7 ± 4.4 | 90.2 ± 4.4 | 0.204 | 92.2 ± 4.3 | 91.4 ± 4.6 | 0.211 | 0.780 |
Female | 89.5 ± 3.9 | 89.1 ± 4.31 | 0.397 | 89.6 ± 3.9 | 88.7 ± 3.6 | 0.124 | 0.503 |
MCH (pg) | 30.1 ± 2.1 | 30.1 ± 1.9 | 0.850 | 30.0 ± 1.5 | 30.0 ± 1.4 | 0.940 | 0.861 |
Male | 30.6 ± 2.2 | 30.7 ± 2.0 | 0.651 | 30.4 ± 1.6 | 30.4 ± 1.5 | 0.842 | 0.658 |
Female | 29.5 ± 1.8 | 29.5 ± 1.8 | 0.801 | 29.5 ± 1.1 | 29.5 ± 1.1 | 0.910 | 0.810 |
MCHC (%) | 33.4 ± 1.6 | 33.6 ± 1.4 | 0.108 | 33.0 ± 1.2 | 33.3 ± 0.9 | 0.041* | 0.673 |
Male | 33.8 ± 1.9 | 34.1 ± 1.7 | 0.116 | 33.0 ± 1.2 | 33.2 ± 1.1 | 0.267 | 0.794 |
Female | 32.9 ± 1.1 | 33.1 ± 0.9 | 0.533 | 32.9 ± 1.1 | 33.3 ± 0.7 | 0.061 | 0.335 |