Table 2 PBMC subsets and HLA class I and class II expression

% CD3⁺ T cells

72.8 ± 0.8

74.4 ± 1.0

74.2 ± 1.5

72.2 ± 1.7

78.9 ± 1.5

p value

0.216*

< 0.05

% CD4⁺CD3⁺ T cells

46.2 ± 1.1

52.2 ± 1.2

49.7 ± 1.9

51.1 ± 1.8

58.1 ± 1.9

p value

< 0.001*

< 0.05

< 0.001

% CD8⁺CD3⁺ T cells

23.1 ± 0.8

19.8 ± 0.7

21.7 ± 1.1

18.8 ± 1.0

18.3 ± 1.6

p value

0.007†

< 0.01

< 0.05

CD4:CD8 ratio

2.2 ± 0.1

3.0 ± 0.2

2.5 ± 0.2

3.0 ± 0.3

3.7 ± 0.5

p value

< 0.001†

< 0.01

< 0.001

% NK cells

8.1 ± 0.6

8.1 ± 0.6

9.1 ± 1.1

8.0 ± 1.1

6.5 ± 1.0

p value

0.553†

% B cells

13.1 ± 0.6

11.7 ± 0.7

11.1 ± 1.1

13.0 ± 1.1

10.5 ± 1.1

p value

0.143*

% monocytes

7.7 ± 0.6

7.6 ± 0.6

8.2 ± 1.1

8.1 ± 1.0

5.4 ± 1.0

p value

0.752†

T cell HLA class I MFI

2015 ± 60

2072 ± 46

1964 ± 61

2082 ± 73

2223 ± 107

p value

0.445*

T cell HLA class II MFI

14.0 ± 0.5

13.7 ± 0.6

13.3 ± 0.8

13.3 ± 0.7

15.0 ± 1.7

p value

0.406†

B cell HLA class I MFI

3838 ± 132

4063 ± 123

4037 ± 231

3919 ± 164

4362 ± 261

p value

0.214*

B cell HLA class II MFI

4384 ± 146

4273 ± 153

4313 ± 210

3951 ± 265

4784 ± 315

p value

0.605*

Monocyte HLA class I MFI

4948 ± 221

4941 ± 189

4823 ± 282

4837 ± 355

5322 ± 297

p value

0.982*

Monocyte HLA class II MFI

2587 ± 218

2907 ± 236

3053 ± 418

2578 ± 317

3254 ± 561

p value

0.474†