Table 1 Reported and rearranged data from MS incidence surveys presented in Figure 3

Debouverie 2007 [31]

0-14

0

3,070,347

0.00

7

2,911,480

0.24

7

5,981,827

0.12

15-24

59

2,191,949

2.69

213

2,072,309

10.28

272

4,264,258

6.38

25-34

154

2,236,211

6.89

445

2,199,900

20.23

599

4,436,111

13.50

35-44

151

2,262,937

6.67

339

2,249,492

15.07

490

4,512,429

10.86

45-54

93

1,827,995

5.09

137

1,782,369

7.69

230

3,610,364

6.37

55-64

21

1,458,543

1.44

32

1,542,168

2.08

53

3,000,711

1.77

65+

2

1,680,520

0.12

5

2,584,219

0.19

7

4,264,739

0.16

Guidetti 1995 [36]

0-14

0

449,088

0.00

0

428,838

0.00

0

877,926

0.00

15-24

12

437,867

2.74

20

424,286

4.71

32

862,153

3.71

25-34

7

429,913

1.63

25

425,059

5.88

32

854,972

3.74

35-44

9

420,283

2.14

16

419,570

3.81

25

839,853

2.98

45-54

1

407,265

0.25

11

409,216

2.69

12

816,481

1.47

55-64

0

384,447

0.00

2

416,345

0.48

2

800,792

0.25

65+

0

414,027

0.00

0

595,139

0.00

0

1,009,166

0.00

Alonso 2007 [48]

0-14

0

1,114,646

0.00

0

1,061,240

0.00

0

2,175,886

0.00

15-24

6

711,643

0.84

24

700,702

3.43

30

1,412,345

2.12

25-34

50

928,136

5.39

115

926,436

12.41

165

1,854,572

8.90

35-44

57

860,894

6.62

155

837,502

18.51

212

1,698,396

12.48

45-54

51

800,963

6.37

111

780,853

14.22

162

1,581,816

10.24

55-64

29

592,600

4.89

31

596,522

5.20

60

1,189,122

5.05

65+

5

754,786

0.66

8

1,078,718

0.74

13

1,833,504

0.71

Nicoletti 2005 [32]

0-14

2

297,120

0.67

1

281,850

0.35

3

578,970

0.52

15-24

10

251,490

3.98

19

246,740

7.70

29

498,230

5.82

25-34

22

237,360

9.27

34

240,670

14.13

56

478,030

11.71

35-44

12

205,920

5.83

25

226,150

11.05

37

432,070

8.56

45-54

7

177,620

3.94

17

203,130

8.37

24

380,750

6.30

55-64

3

158,980

1.89

3

193,760

1.55

6

352,740

1.70

65+

0

205,740

0.00

0

295,230

0.00

0

500,970

0.00

Joensen 2010 [40]

0-14

0

125,615

0.00

0

118,653

0.00

0

244,268

0.00

15-24

3

81,263

3.69

6

69,516

8.63

9

150,779

5.97

25-34

5

74,267

6.73

9

63,934

14.08

14

138,201

10.13

35-44

6

75,305

7.97

5

66,389

7.53

11

141,694

7.76

45-54

3

64,103

4.68

5

55,218

9.06

8

119,321

6.70

55-64

0

49,604

0.00

1

44,487

2.25

1

94,091

1.06

65+

0

59,298

0.00

1

71,896

1.39

1

131,194

0.76

Sundstrom 2003 [37]

0-14

1

255,257

0.40

1

244,079

0.40

2

499,336

0.40

15-24

5

175,802

2.90

14

169,431

8.40

19

345,233

5.60

25-34

18

179,111

10.00

32

166,142

19.20

50

345,253

14.40

35-44

16

182,644

8.70

23

171,520

13.40

39

354,164

10.90

45-54

7

163,908

4.20

12

157,093

7.50

19

321,001

5.90

55-64

0

126,402

0.00

4

131,128

3.10

4

257,530

1.60

65+

0

189,679

0.00

0

239,325

0.00

0

429,004

0.00

Granieri 2007 [34]

0-14

0

247,388

0.00

2

232,900

0.86

2

480,288

0.42

15-24

10

282,723

3.54

17

267,370

6.36

27

550,093

4.91

25-34

21

370,041

5.68

55

353,479

15.56

76

723,520

10.50

35-44

13

348,169

3.73

41

349,768

11.72

54

697,937

7.74

45-54

8

336,728

2.38

18

350,939

5.13

26

687,667

3.78

55-64

1

331,387

0.30

4

366,978

1.09

5

698,365

0.72

65+

0

443,139

0.00

2

656,512

0.30

2

1,099,651

0.18

Granieri 2008 [35]

0-14

0

31,856

0.00

0

28,859

0.00

0

60,708

0.00

15-24

2

25,489

7.85

4

24,735

16.17

6

50,196

11.95

25-34

3

35,513

8.45

11

40,625

27.08

14

76,022

18.42

35-44

0

32,290

0.00

5

33,221

15.05

5

65,509

7.63

45-54

2

27,336

7.32

2

27,582

7.25

4

54,887

7.29

55-64

1

22,396

4.47

2

22,356

8.95

3

44,736

6.71

65+

0

27,157

0.00

1

36,490

2.74

1

63,483

1.58

Nicoletti 2010 [10]

0-14

0

129,630

0.00

0

122,860

0.00

0

252,490

0.00

15-24

3

103,300

2.90

13

101,785

12.77

16

205,085

7.80

25-34

10

115,110

8.69

27

114,755

23.53

37

229,865

16.10

35-44

11

104,500

10.53

20

114,380

17.49

31

219,880

14.10

45-54

11

98,320

11.19

8

105,025

7.62

19

198,345

9.58

55-64

4

76,320

5.24

1

91,740

1.09

5

168,060

2.98

65+

0

111,475

0.00

0

167,980

0.00

0

275,855

0.00

Cabre 2009 [8]

0-14

1

1,388,049

0.07

2

1,351,144

0.15

3

2,739,193

0.11

15-24

6

848,215

0.71

17

837,479

2.03

23

1,685,694

1.36

25-34

8

808,481

0.99

35

926,145

3.78

43

1,734,626

2.48

35-44

7

814,933

0.86

30

931,847

3.22

37

1,746,780

2.12

45-54

2

608,781

0.33

18

699,425

2.57

20

1,308,206

1.53

55-64

1

447,677

0.22

2

511,278

0.39

3

958,955

0.31

65+

0

530,373

0.00

1

731,100

0.14

1

1,261,473

0.08