Figure 2From: Nuclear entrapment and extracellular depletion of PCOLCE is associated with muscle degeneration in oculopharyngeal muscular dystrophy Transverse cryosections of VL muscle biopsies from an OPMD patient over a 6Â year interval. A) Biopsy taken at the time of first presentation in the clinic. B) Biopsy of the same muscle as in (A) taken 6Â years later. Sections were stained with haematoxylin-eosin. Muscle fibrosis is evidenced by fat infiltration (F), vacuole with basophilic rim (arrowhead) and thickening of the ECM (arrows). Scale bar equals 100Â ÎĽm.Back to article page