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Figure 1 | BMC Neurology

Figure 1

From: Is a hypothetical melanoma-like neuromelanin the underlying factor essential for the aetiopathogenesis and clinical manifestations of multiple sclerosis?

Figure 1

Schematic description of normal neuromelanin and melanoma-like neuromelanin (MLN). Partial structures of the subunits A: 5,6-dihydroxyindole-2-carboxylic acid, B: the oxidised ortho-quinone form, and C: an initial product formed upon reaction of B with H2O2; 'red point symbol': iron (Fe2+). MLN has a greater tendency to become oxidatively charged (increased B/A-ratio) indicated in the background by stronger blue shading.

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BMC Neurology

ISSN: 1471-2377

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