Table 2 Hospitalization: stroke severity, neurological and medical complications, disability at discharge
Emergency treatment: | All (n = 12750) | Statin + |  | p-value | |
|---|---|---|---|---|---|
Intravenous thrombolysis | 544 (4.3%) | 294 (54%) |  | p < 0.0001 | |
Intra-arterial thrombolysis | 92 (0.7%) | 37 (40%) | Â | Â | |
No thrombolysis | 12114 (95%) | 5061 (42%) | Â | Â | |
Stroke severity (NIHSS): |  | NIHSS ≤ 8 | NIHSS >8 |  | |
At admission available in 8470 pts | NIHSS ≤ 8: 6199 (73%) | 2846 (46%) | 849 (37%) | p < 0.0001 | |
NIHSS >8: 2271 (27%) | Â | Â | Â | ||
At discharge available in 8132 pts | NIHSS ≤ 8: 6691 (82%) | 3171 (47%) | 544 (38%) | p < 0.0001 | |
NIHSS >8: 1441 (18%) | Â | Â | |||
mRS at discharge available in 7958 pts | mRS 0–1: 3487 (44%) | mRS 0-1 | mRS 2-5 | p < 0.0001 | |
mRS 2–5: 4471 (56%) | 1707 (49%) | 1847 (41%) | |||
In-hospital complications, n (%) | Â | Present | Absent | Â | |
Intracranial hypertension | 427 (3.5%) | 170 (40%) | 5222 (42%) | p = 0.29 | |
Acute myocardial infarction | 37 (0.3%) | 22 (59%) | 5370 (42%) | p = 0.03 | |
Seizures | 270 (2%) | 91 (34%) | 5301 (42%) | p = 0.004 | |
Hypoxemia | 782 (6%) | 250 (32%) | 5142 (43%) | p < 0.0001 | |
Hypertensive fits | 2240 (18%) | 1060 (47%) | 4332 (41%) | p < 0.0001 | |
Hyperglycemia | 1136 (9%) | 579 (51%) | 4813 (41%) | p < 0.0001 | |
Atrial fibrillation/flutter | 931 (7%) | 324 (35%) | 5068 (43%) | p < 0.0001 | |
Fever | 1922 (15%) | 683 (35%) | 4709 (43%) | p < 0.0001 | |
Ventricular arrhythmia | 57 (0.5%) | 24 (42%) | 5368 (42%) | p = 0.97 | |
Bedsores | 195 (1.5%) | 40 (20.5%) | 5352 (43%) | p < 0.0001 | |
Deep venous thrombosis/pulmonary embolism | 49 (0.4%) | 16 (33%) | 5376 (42%) | p = 0.17 | |
Bleedings | 547 (4%) | 182 (33%) | 5210 (43%) | p < 0.0001 | |
Urinary infections | 1276 (10%) | 431 (34%) | 4961 (43%) | p < 0.0001 | |
Falls | 158 (1%) | 69 (44%) | 5323 (42%) | p = 0.72 | |
Pneumonia | 419 (3%) | 130 (31%) | 5262 (43%) | p < 0.0001 | |
Psychiatric disorders | 488 (4%) | 193 (39.5%) | 5199 (42%) | p = 0.21 | |
Diagnosis at discharge | Â | Ischemic stroke | TIA | Â | |
Ischemic stroke/TIA | 10534 (83%) | 4482 (43%) | 906 (41%) | p = 0.14 | |
TOAST classification available in 8564 patients | Â | All | With other indications to prescription* | Without other indications to prescription | Â |
Cardioembolism (possible/probable) | 3083 (36%) With* other indications to prescription: 1059; without 2024 | 1113 (36%) | 542 (51%) | 571 (28%) | p < 0.0001 |
Non-cardioembolism: | 5481 (54%) With* other indications to prescription: 1819; without 3662 | 2607 (47%) | 1185 (65%) | 1422(39%) | |
 -Large vessels atherosclerosis | 2078 (24%) With* other indications to prescription: 766; without 1312 | 1077 (52%) | 504 (66%) | 573 (44%) | |
 -Small vessels disease | 1983 (23%) With* other indications to prescription: 668; without 1315 | 979 (49%) | 458 (68%) | 521 (40%) | |
 -Other causes | 178 (2%) With* other indications to prescription: 43; without 135 | 48 (27%) | 24 (56%) | 24 (18%) | |
 -Undetermined etiology | 1242 (15%) With* other indications to prescription: 342; without 900 | 503 (40%) | 199 (58%) | 304 (34%) | |
Antithrombotic treatment at discharge | Â | Â | Â | Â | Â |
Antiplatelet | 9763 (76%) | 4296 (44%) | p < 0.0001 | ||
Anticoagulant | 2130 (17%) | 933 (42.8%) | |||
None | 857 (7%) | 163 (19%) | Â | ||