Table 1 Demographic data and clinical manifestations of painful ophthalmoplegia with normal neuroimaging
Ocular diabetic neuropathy | Benign Tolosa-Hunt syndrome | Ophthalmoplegic migraine | Total | pvalue | |
|---|---|---|---|---|---|
N (%) | 25 (47.2) | 25 (47.2) | 3 (5.7 ) | 53 | |
N of episodes | 26 | 27 | 5 | 58 | |
M/F | 12/13 | 10/15 | 3/0 | 25/28 | |
Age (year) | 62.8 ± 7.8 | 56.3 ± 12.0 | 45.8 ±23.0 | 58.3 ± 12.4 | 0.008* |
Involvement of cranial nerves, N (%) | |||||
CN3 | 19 (73.1) | 20 (74.1) | 4 (80.0) | 43 (74.1) | 0.949 |
CN4 | 9 (34.6) | 15 (55.6) | 2 (40.0) | 23 (39.7) | 0.301 |
CN6 | 13 (50.0) | 16 (59.3) | 2 (40.0) | 31 (53.4) | 0.652 |
Ptosis | 16 (61.5) | 11 (40.7) | 1 (20.0) | 28 (48.3) | 0.132 |
Pupillary dysfunction | 7 (26.9) | 6 (22.2) | 0 (0.0) | 13 (22.4) | 0.417 |
Multiple CNs involvement | 10 (38.5) | 18 (66.7) | 3 (60.0) | 31 (53.4) | 0.115 |
Laboratory data | |||||
ESR (mm/hr) | 29.4.2 ± 28.0 | 14.2 ± 21.7 | 9.6 ± 8.4 | 0.070 | |
HbA1c (%) | 8.3 ± 1.8 | 5.9 ± 2.5 | 6.2 ± 0.6 | 0.003* | |
Recurrence, N of patients (%) | 1 (4.0) | 2 (8.0) | 1 (33.3) | 0.190 | |
Duration of course (month) | 2.0 ± 1.0 | 1.6 ± 0.8 | 0.9 ± 0.4 | 1.7 ± 0.9 | 0.044* |
Duration of follow-up (year) | 3.4 ± 3.1 | 4.9 ± 3.6 | 3.6 ± 0.3 | 4.0 ± 3.3 | |
Total recovery, N (%) | 24 (92.3) | 26 (96.3) | 5 (100.0) | 55 (94.8) | 0.695 |