Quality of life outcomes | Incontinence status | ||||||
---|---|---|---|---|---|---|---|
Base-case analysis | Sensitivity analysis | ||||||
Incontinence (Yes vs. No) | R2 | Average number of UI episodes per day | R2 | Number of UI episodes (Ordinal)c | R2 | ||
EQ-5D utility score a | −0.04 (0.03) | 0.21 | −0.01 (0.00)* | 0.22 | 0 ≤ n ≤ 4 | −0.02 (0.03) | 0.22 |
n > 4 | −0.07 (0.03)* | ||||||
I-QOL score a | −10.39 (2.52)*** | 0.25 | −1.03 (0.29)*** | 0.24 | 0 ≤ n ≤ 4 | −8.47 (2.69)** | 0.26 |
n > 4 | −13.66 (2.97)*** | ||||||
OAB-q symptom severity score a | 15.01 (2.58)*** | 0.22 | 1.65 (0.29)*** | 0.22 | 0 ≤ n ≤ 4 | 11.92 (2.72)*** | 0.25 |
n > 4 | 20.27 (3.01)*** | ||||||
OAB-q HRQL total score a | −8.69 (2.72)** | 0.19 | −1.03 (0.30)*** | 0.19 | 0 ≤ n ≤ 4 | −6.63 (2.89)* | 0.20 |
n > 4 | −12.22 (3.18)*** | ||||||
WPAI – percent activity impairment due to problem a | 8.23 (3.41)* | 0.15 | 1.40 (0.38)*** | 0.17 | 0 ≤ n ≤ 4 | 4.88 (3.62) | 0.17 |
n > 4 | 13.95 (4.03)** | ||||||
WPAI – percent work time miss due to problem‡ a,b | 3.69 (5.66) | 0.22 | 1.51 (1.15) | 0.24 | 0 ≤ n ≤ 4 | 3.51 (5.90) | 0.22 |
n > 4 | 4.71 (8.98) | ||||||
WPAI – percent impairment while working due to problem‡ a,b | 3.70 (7.13) | 0.28 | 3.14 (1.42)* | 0.34 | 0 ≤ n ≤ 4 | 1.69 (7.16) | 0.31 |
n > 4 | 15.93 (11.33) | ||||||
WPAI – percent overall work impairment due to problem‡ a,b | 3.04 (8.96) | 0.27 | 1.94 (1.79) | 0.28 | 0 ≤ n ≤ 4 | 3.30 (9.30) | 0.27 |
n > 4 | 1.21 (13.88) |