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Table 1 Adjusted least square means by treatment and time from the two-group, repeated measures ANOVA model results.

From: Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats

Outcome

Minocycline

Saline

 

10'

90'

240'

360'

10'

90'

240'

360'

 

Mean

SE

Mean

SE

Mean

SE

Mean

SE

Mean

SE

Mean

SE

Mean

SE

Mean

SE

Blood Pressure

102.33

2.68

102.50

2.68

102.00

2.68

100.00

2.68

113.17

2.68

102.83

2.68

101.33

2.68

98.67

2.68

Heart Rate

335.00

14.36

364.33

14.36

342.67

14.36

368.67

14.36

340.50

14.36

332.00

14.36

322.83

14.36

326.50

14.36

Temperature

36.87

0.07

37.02

0.07

37.05

0.07

37.08

0.07

37.17

0.07

37.00

0.07

36.93

0.07

37.00

0.07

pH

7.45

0.01

7.43

0.01

7.43

0.01

7.45

0.01

7.45

0.01

7.44

0.01

7.44

0.01

7.45

0.01

P02

115.83

4.84

115.83

4.84

114.83

4.84

110.67

4.84

121.00

4.84

124.67

4.84

117.17

4.84

117.50

4.84

PC02

43.17

0.87

43.66

0.87

44.50

0.87

43.17

0.87

44.17

0.87

44.00

0.87

43.83

0.87

44.17

0.87

Glucose

176.00

8.37

186.33

8.37

202.33

8.37

178.67

8.37

186.00

8.37

220.67

8.37

209.50

8.37

200.17

8.37

  1. There were no statistically significant differences between the Minocycline or saline groups within any time point for any of the outcome measures