Table 3 Characteristics Associated with Medication Nonpersistence at Six Months in the 420 Patients Enrolled in the Stroke Outcome Study from 2001–2002 at the Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
Characteristic | Antihypertensive | Antithrombotic | Antilipidemic | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Â | Not Persistenta | Unadj OR | Adj OR | Not Persistenta | Unadj OR | Adj OR | Not Persistenta | Unadj OR | Adj OR |
Stroke Cohort | 21/384 (5.5) | Â | Â | 20/405 (4.9) | Â | Â | 22/307 (7.2) | Â | Â |
Age (years) | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   < 65 | 7/112 (6.3) | 0.42 (0.16, 1.13) | 0.37 (0.13, 1.03) | 9/130 (6.9) | 0.82 (0.29, 2.29) | 0.92 (0.32, 2.65) | Not significant |  |  |
   65–79 | 3/192 (1.6) | 0.10 (0.03, 0.37) | 0.11 (0.03, 0.39) | 4/191 (2.1) | 0.24 (0.07, 0.83) | 0.23 (0.06, 0.81) |  |  |  |
   ≥ 80 | 11/80 (13.8) | 1.00 | 1.00 | 7/84 (8.3) | 1.00 | 1.00 |  |  |  |
Total medications prescribedb | Â | 0.80 (0.65, 0.995) | Â | Not significant | Â | Â | Not significant | Â | Â |
Monthly drug costsc | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   < $90.00 | 7/78 (9.0) | 7.05 (1.43, 34.81) | 6.74 (1.32, 34.46) | Not significant |  |  | Not significant |  |  |
   $90.00 – $199.99 | 12/161 (7.5) | 5.76 (1.27, 26.18) | 5.25 (1.14, 24.25) |  |  |  |  |  |  |
   ≥ $200.00 | 2/145 (1.4) | 1.00 | 1.00 |  |  |  |  |  |  |
OHS impairment before stroke | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Independent | Not significant |  |  | 17/390 (4.4) | 1.00 | 1.00 | Not significant |  |  |
   Dependent |  |  |  | 3/15 (20.0) | 5.49 (1.41, 21.27) | 7.01 (1.66, 29.58) |  |  |  |
OHS impairment at discharge | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Independent | Not significant |  |  | 11/318 (3.5) | 1.00 |  | Not significant |  |  |
   Dependent |  |  |  | 9/87 (10.3) | 3.22 (1.29, 8.04) |  |  |  |  |
Tobacco use before stroke | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Yes | Not significant |  |  | Not significant |  |  | 5/23 (21.7) | 4.35 (1.44, 13.13) | 4.35 (1.44, 13.13) |
   No |  |  |  |  |  |  | 17/283 (6.0) | 1.00 | 1.00 |
History of previous stroke | Â | Â | Â | Â | Â | Â | Â | Â | Â |
   Yes | Not significant |  |  | Not significant |  |  | 1/76 (1.3) | 0.13 (0.02, 1.004) |  |
   No |  |  |  |  |  |  | 21/230 (9.1) | 1.00 |  |