Skip to main content

Table 4 Effect of the APOE ε4 allele on age at onset in LOAD and EOAD

From: APOE ε4 lowers age at onset and is a high risk factor for Alzheimer's disease; A case control study from central Norway

 

Number of APOE ε4-alleles

 

0

 

1

 

2

 

EOAD. Age at onset ± SD, n

57.3 ± 4.0

14

57.3 ± 4.7

16

58.7 ± 2.6

10

LOAD. Age at onset ± SD, n

78.4 ± 5.8

121

75.3 ± 5.8a

168

72.9 ± 5.0b

47

  1. SD = Standard deviation
  2. n = number of patients
  3. EOAD: Early onset Alzheimer's disease (onset < 65 years), no significant difference in onset between carriers of none, one and two APOE ε4 alleles.
  4. LOAD: Late onset Alzheimer's disease (onset ≥ 65 years)
  5. a: The difference between onset in LOAD (Late Onset AD) in carriers of none and one APOE ε4 allele was significant; p = 0.005.
  6. b: The difference between onset in LOAD in carriers of one and two APOE ε4 alleles was significant; p = 0.002.
Back to article page

BMC Neurology

ISSN: 1471-2377

Contact us