Fig. 2
From: Recurrent Nicolau syndrome associated with subcutaneous glatiramer acetate injection—a case report
Histological picture of the patient’s skin biopsy. a partly necrotic and elevated epidermis (dashed arrows) due to thrombosized small vessels (solid arrows) in the upper dermis with only sparse cellular inflammation. b haematoma in the deeper part of dermis (solid arrow). c cellular inflammation in the deeper dermis (solid arrow) and panniculitis (dashed arrow) with coagulative necrosis of dermal collagen and local adipose tissue. Stain: haematoxylin-eosin, a: x 200, b: x 100, c: x 40. Software: ProgRes CapturePro v2.8.8