Table 3 Correlation of MRI features with EDSS in NMOSD subjects

Brain T1 hypointense lesion

No

25

2.6

1.7

0.522

26

2.8

1.7

0.005

51

2.7

1.7

0.022

Yes

12

3.0

1.5

10

4.5

1.1

22

3.7

1.5

Hemispheric white matter T1 hypointense lesion

None

28

2.4

1.6

0.101

25

2.9

1.7

0.888

53

2.7

1.7

0.014

 < 2 cm

9

2.8

1.6

4

4.4

1.4

13

3.3

1.7

 =  > 2 cm

3

4.7

1.1

4

4.5

0.9

7

4.6

0.9

Corticospinal tract T1 hypointense lesion

No

36

2.6

1.6

0.051

34

3.2

1.7

0.680

70

2.9

1.7

0.112

Yes

1

6.0

2

3.7

1.8

3

4.5

1.8

Periependymal (Lateral Ventricles) T1 hypointense lesion

No

34

2.7

1.6

0.342

39

3.2

1.7

0.875

73

3.0

1.7

0.915

Yes

0

-

0

-

0

-

Periependymal (3rd and 4th ventricles) T1 hypointense lesion

No

34

3.0

1.4

0.065

36

2.8

1.8

0.574

70

2.9

1.7

0.216

Yes

1

5.0

2

3.7

1.8

3

4.2

2

Cord T1 hypointense lesion

No

28

2.7

1.7

0.022

27

2.8

1.7

0.121

55

2.7

1.7

0.055

Yes

8

2.7

1.7

10

4.6

0.9

18

3.6

1.6

Brain T2/FLAIR hyperintense lesions

No

12

2.2

1.8

0.212

15

2.4

1.6

0.014

27

2.3

1.7

0.013

Yes

25

2.9

1.6

21

3.8

1.6

46

3.3

1.6

Cord T2/FLAIR hyperintense lesions

No

1

5.0

0.162

3

2.0

1.0

0.194

4

2.7

1.7

0.790

Yes

36

2.6

1.6

33

3.4

1.7

69

3.0

1.7