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Table 2 comparison of motor characteristics between Parkinson’s disease and vascular parkinsonism

From: The clinical and neuroimaging differences between vascular parkinsonism and Parkinson’s disease: a case-control study

 

Parkinson’s disease

(No. =48)

Vascular parkinsonism

(No. =27)

Mann Whitney U test / Chi-square test^

Median (IQR/Range)

Median (IQR/Range)

z/ x

p

AOO (years)

53.25(40–74)

65 (41–71)

-3.552

< 0.001*

DOI (years)

5 (1.50–14)

3 (1–10)

-2.693

0.007*

Onset ^

Gradual

48 (100%)

17 (63%)

 

Acute

0 (0%)

10 (37%)

Motor subtypes

Tremor dominant

37 (77.1%)

7 (25.9%)

20.867

< 0.001*

PIGD

6 (12.5%)

16 (59.3%)

Indeterminate subtype

5 (10.4%)

4 (14.8%)

Parkinson Asymmetry^

9 (18.75%)

2 (7.40%)

-5.21

< 0.001*

Symmetry index^

(Asymmetrical subjects)

34 (70.4%)

7 (25.9%)

14.062

< 0.001*

Lower parkinsonism^

6 (12.5%)

11 (40.7%)

7.862

0.005*

MDS-UPDRS total score OFF

80.50 (61)

79 (21)

-0.574

0.566

MDS-UPDRS total score ON

61 (42)

71(21)

-1.512

0.130

MDS-UPDRS part I

16.5 (10)

16 (5)

-0.746

0.455

MDS-UPDRS Part II

16 (17)

18(8)

-0.519

0.604

MDS-UPDRS Part III –OFF

51(31)

45 (14)

-1.016

0.310

MDS-UPDRS Part III –ON

27 (21)

39 (10)

-3.038

0.002*

Rigidity OFF

8 (6)

8 (3)

-0.577

0.564

Rigidity ON

4.50 (5)

7(3)

-3.825

< 0.001*

Bradykinesia OFF

17 (16)

16 (6)

-0.017

0.987

Bradykinesia ON

8.50 (10)

14 (7)

-2.113

0.035*

PIGD OFF

6.50 (10)

9 (2)

-1.881

0.060

PIGD ON

4 (7)

9 (2)

-3.543

< 0.001*

Axial OFF

12.50 (12)

16 (4)

-2.195

0.028*

Axial Score ON

7 (9)

15 (4)

-5.066

< 0.001*

Tremor score OFF

14 (11)

5 (13)

-4.418

< 0.001*

Tremor score ON

9 (7)

5 (8)

-3.310

< 0.001*

Constancy of rest tremors off

2 (2)

0 (2)

-4.477

< 0.001*

Constancy of rest tremors on

1 (1)

0 (2)

-2.709

0.007*

H&Y OFF

2.5 (1.5-4)

3 (2–5)

-3.373

< 0.001*

H&Y ON

2 (1–3)

3 (2–5)

-4.758

< 0.001*

S&E ADL OFF

80 (17.50)

60 (10)

-4.208

< 0.001*

S&E ADL ON

90 (10)

60 (20)

-5.254

< 0.001*

Motor complication total score

5 (8)

4 (2)

-1.272

0.203

NFOG-Q OFF

26 (54.2%)

5 (18.5%)

9.056

0.003*

NFOG-Q ON

21(43.8%)

5 (18.5%)

4.857

0.028*

BBS OFF

47.50 (14)

33 (9)

-4.541

< 0.001*

BBS ON

54 (9)

36 (12)

-5.505

< 0.001*

TUG OFF

12.90 (12.25)

16.12 (9.74)

-1.761

0.078

TUG ON

10.65 (6.16)

13.55 (8.31)

-2.936

0.003*

10-MWT, Comfortable speed OFF (meter/sec)

0.797 (0.435)

0.712 (0.347)

-1.496

0.135

10-MWT, Comfortable speed ON (meter/sec)

0.91 (0.412)

0.83 (0.389)

-1.887

0.059

Urine incontinence scale

1 (3)

2 (1)

2.463

0.014*

IPAQ total score

1790 (1283.3)

417 (954)

5.603

< 0.001*

LEDD Mean (SD)**

631.48 (398.76)

415.74 (126.94)

3.45

< 0.001*

Dopa responsive (%)^

44 (91.7%)

7 (25.9%)

34.321

< 0.001*

  1. AOO, age of onset; DOI, duration of illness; LEDD, Levodopa equivalent daily dose; MDS-UPDRS, Movement Disorder Society—Unified Parkinson’s Disease Rating Scale, PIGD postural instability –gait difficulty; H & Y, Hoehn and Yahr scale for Parkinson; S&E, Schwab and England ADL Scale; ADL, activities of daily living; NFOG-Q; new freezing of gait questionnaire; BBS, berg balance scale; TUG, time up and go test; 10 MWT, 10-meter walk test. IPAQ, international physical activity questionnaire,
  2. ^ Chi-square test is used
  3. ** T-test is used
  4. *p value is significant