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Table 3 Non-motor functions and quality of life among people with Parkinson’s disease and vascular parkinsonism

From: The clinical and neuroimaging differences between vascular parkinsonism and Parkinson’s disease: a case-control study

 

Parkinson’s disease

(No. =48)

Vascular parkinsonism

(No.=27)

Control

(No. =29)

Kruskal-Wallis Test

Parkinson’s disease

vs. Vascular parkinsonisma

Parkinson’s disease

vs. controla

Vascular 541

vs. controla

Median (Range/ IQR)

Median (Range/ IQR)

Median (Range/ IQR)

P

P

P

p

Non-motor Symptoms Sclae

NMSS total score

55 (4-205/ 47)

39 (10–100/ 30)

7 (1–33/ 6)

< 0.001*

0.030*

< 0.001*

< 0.001*

Cardiovascular

1 (2)

2(3)

0(0)

< 0.001*

0.688

< 0.001*

< 0.001*

Sleep/fatigue

8 (8)

6 (6)

0 (1)

< 0.001*

0.031*

< 0.001*

< 0.001*

Mood/Cognition

12 (16)

6 (4)

3 (2)

< 0.001*

0.006*

< 0.001*

< 0.001*

Perceptual problems/ hallucinations

0 (1)

0 (0)

0 (0)

0.102

   

Attention/memory

6 (10)

6 (9)

1 (1)

< 0.001*

0.820

< 0.001*

< 0.001*

Gastrointestinal tract

5 (8)

4 (8)

0 (1)

< 0.001*

0.319

< 0.001*

< 0.001*

Urinary

5.50 (11)

12 (6)

0 (1)

< 0.001*

0.037*

< 0.001*

< 0.001*

Sexual functions

2 (4)

2 (0)

0 (0)

< 0.001*

0.652

< 0.001*

< 0.001*

Miscellaneous

5.50 (7)

1 (2)

0 (1)

< 0.001*

< 0.001*

< 0.001*

0.003*

BDI total score

17 (0–39)

16.00 (5–33)

4.50 (2–9)

< 0.001*

0.675

< 0.001*

< 0.001*

PDQ-39

PDQ total score^

38.72 (30.10)

31.25 (14.95)

7.60 (3.56)

< 0.001*

0.047*

< 0.001*

< 0.001*

Mobility

42.50 (36.88)

60.00 (35.00)

2.50 (3.75)

< 0.001*

0.055

< 0.001*

< 0.001*

ADL

50.00 (53.12)

45.83 (29.17)

0.00 (0.00)

< 0.001*

0.103

< 0.001*

< 0.001*

Emotional wellbeing

39.58 (37.50)

29.17 (20.83)

20.83 (8.33)

< 0.001*

0.044*

< 0.001*

< 0.001*

Stigma

68.75 (48.44)

31.25 (50.00)

0.00 (0.00)

< 0.001*

< 0.001*

< 0.001*

< 0.001*

Social support

16.66 (37.50)

0.00 (8.33)

0.00 (0.00)

< 0.001*

< 0.001*

< 0.001*

0.002*

Cognition

25.00 (31.25)

37.50 (18.75)

12.50 (18.75)

< 0.001*

0.266

< 0.001*

< 0.001*

Communication

33.33 (39.59)

25.00 (25.07)

0.00 (0.00)

< 0.001*

0.388

< 0.001*

< 0.001*

Bodily discomfort

41.66 (25.00)

33.33 (16.67)

25.00 (16.73)

< 0.001*

0.003*

< 0.001*

0.651

Cognitive Scales

       

MOCA total score

22(6–29)

19.00 (12–24)

24 (17–27)

< 0.001*

0.015*

0.014*

< 0.001*

FAB total score

13 (2–17)

9.00 (6–14)

13.50 (9–17)

< 0.001*

0.001*

0.091

< 0.001*

WMS total score

41.75 (11.4)

38 (13.0)

47 (10.3)

< 0.001*

0.006*

0.040*

< 0.001*

Verbal fluency of ACE-III

1 (3)

0 (0)

1 (1)

< 0.001*

< 0.001*

0.974

< 0.001*

Clock drawing of ACE-III

3 (3)

3 (2)

5(2)

< 0.001*

0.602

< 0.001*

< 0.001*

  1. NMSS: non-motor symptoms scale; PDQ-39: Parkinson’s disease questionnaire-39, ADL: activities of daily living, MOCA: Montreal cognitive assessment; FAB: Frontal Assessment Battery; BDI: Beck depression inventory; WMS: Wechsler memory scale; ACE-III: Addenbrooke’s Cognitive Examination -III
  2. a Mann Whitney U test was used
  3. *p-value is significant
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BMC Neurology

ISSN: 1471-2377

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