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Table 1 Clinical characteristics

From: Differential expression of Semaphorin-7A /CD163-positive macrophages in large artery and cardiogenic stroke

Variables

Total (n = 67)

CE (n = 42)

LAA (n = 25)

Statistic

P

Age, Median (Q1, Q3)

68 (59, 75)

72.5 (59.5, 77)

68 (60, 73)

601

0.327

Gender, n (%)

   

0.658

0.417

 Female

27 (40)

19 (45)

8 (32)

  

 Male

40 (60)

23 (55)

17 (68)

  

Systolic blood pressure, Mean ± SD

152.04 ± 24.8

152.76 ± 23.52

150.84 ± 27.28

0.293

0.771

Diastolic blood pressure, Mean ± SD

85.4 ± 14.3

86.07 ± 12.52

84.28 ± 17.11

0.456

0.651

Glucose, Median (Q1, Q3)

6.7 (6.27, 8.09)

6.68 (6.18, 7.79)

6.85 (6.5, 8.25)

450

0.334

NHISS, Mean ± SD

15.22 ± 7.02

15.45 ± 7.37

14.84 ± 6.53

0.354

0.725

Hypertension, n (%)

41 (61)

22 (52)

19 (76)

2.754

0.097

Diabetes mellitus, n (%)

10 (15)

4 (10)

6 (24)

Fisher

0.157

Smoking, n (%)

19 (28)

8 (19)

11 (44)

3.653

0.056

Treatment, n (%)

   

0.008

0.929

 no-rtPA

42 (63)

27 (64)

15 (60)

  

 rtPA

25 (37)

15 (36)

10 (40)

  

90 day-mRS, n (%)

   

1.519

0.218

 0–2

22 (33)

11 (26)

11 (44)

  

 3–6

45 (67)

31 (74)

14 (56)

  

Sema7A, Median (Q1, Q3)

2 (1.12, 3.38)

2.5 (1.56, 3.94)

1 (0.25, 1.25)

831.5

< 0.001

rSema7A, Median (Q1, Q3)

0.06 (0.04, 0.11)

0.09 (0.06, 0.12)

0.03 (0.01, 0.07)

798

< 0.001

CD163, Median (Q1, Q3)

0.25 (0, 1.38)

0.62 (0, 1.44)

0 (0, 0.5)

616.5

0.218

rCD163, Median (Q1, Q3)

0.01 (0, 0.08)

0.02 (0, 0.08)

0 (0, 0.1)

598

0.327

  1. Abbreviation large-artery atherosclerosis (LAA), cardioembolism (CE), the National Institutes of Health Stroke Scale (NIHSS), recombinant tissue plasminogen activator (rt-PA, the modified Rankin score (mRS) and semaphorin-7A (Sema7A). The macrophage ratios (the number of positive macrophages divide the number of all macrophages) regarding Sema7A and CD163 were abbreviated as rSema7A and rCD163