Table 1 Baseline characteristics of the patients and hospitals
From: Geographic differences in pharmacotherapy patterns and outcomes of acute ischemic stroke in China
|  | All (N = 9973) | East (N = 4806) | Northeast (N = 2552) | Central (N = 2024) | West (N = 591) | P |
|---|---|---|---|---|---|---|
Age, years, median (IQR) | 64 (56–73) | 65 (56–73) | 63 (56–71) | 64 (55–73) | 64 (55–74) | 0.009 |
Female, n (%) | 3415 (34.2) | 1616 (33.6) | 861 (33.7) | 720 (35.6) | 218 (36.9) | 0.21 |
Medical insurance a, n (%) | 8218 (82.5) | 3805 (79.3) | 2129 (83.5) | 1837 (90.8) | 447 (75.6) | < 0.001 |
Medical history, n (%) | ||||||
 Hypertension | 6423 (64.4) | 3146 (65.5) | 1637 (64.1) | 1302 (64.3) | 338 (57.2) | 0.001 |
 Diabetes | 2568 (25.7) | 1267 (26.4) | 683 (26.8) | 479 (23.7) | 139 (23.5) | 0.038 |
 Dyslipidemia | 317 (3.2) | 190 (4) | 33 (1.3) | 77 (3.8) | 17 (2.9) | < 0.001 |
 Atrial fibrillation | 429 (4.3) | 204 (4.2) | 143 (5.6) | 61 (3.0) | 21 (3.6) | < 0.001 |
 Previous stroke | 2364 (23.7) | 929 (19.3) | 815 (31.9) | 506 (25.0) | 114 (19.3) | < 0.001 |
 Coronary heart disease | 1373 (13.8) | 596 (12.4) | 428 (16.8) | 284 (14.0) | 65 (11.0) | < 0.001 |
 Tumor | 243 (2.4) | 128 (2.7) | 65 (2.5) | 45 (2.2) | 5 (0.8) | 0.049 |
GCS score a | Â | |||||
 Median (IQR) | 15 (15–15) | 15 (15–15) | 15 (15–15) | 15 (14–15) | 15 (15–15) | < 0.001 |
 13–15, n (%) | 8993 (90.2) | 4355 (90.6) | 2334 (91.4) | 1788 (88.4) | 516 (87.3) | < 0.001 |
 9–12, n (%) | 758 (7.6) | 339 (7.1) | 170 (6.7) | 185 (9.1) | 64 (10.8) |  |
 3–8, n (%) | 220 (2.2) | 110 (2.3) | 48 (1.9) | 51 (2.5) | 11 (1.9) |  |
NIHSS score a | Â | |||||
 Median (IQR) | 4 (2–7) | 4 (2–8) | 4 (2–7) | 4 (2–8) | 4 (2–8) | < 0.001 |
 ≤ 3, n (%) | 4489 (45.0) | 2110 (43.9) | 1273 (49.9) | 847 (41.9) | 259 (43.8) | < 0.001 |
 4–25, n (%) | 5408 (54.2) | 2652 (55.2) | 1269 (49.7) | 1157 (57.2) | 330 (55.8) |  |
 ≥ 26, n (%) | 73 (0.7) | 42 (0.9) | 10 (0.4) | 19 (0.9) | 2 (0.3) |  |
Stroke etiology (TOAST criteria) b | < 0.001 | |||||
 Large artery atherosclerosis, n (%) | 2889(64.6) | 848(59.0) | 832(75.7) | 1129(63.2) | 80(52.6) |  |
 Cardioembolism, n (%) | 191(4.3) | 67(4.7) | 58(5.3) | 55(3.1) | 11(7.2) |  |
 Small vessel occlusion, n (%) | 1130(25.3) | 457(31.8) | 101(9.2) | 525(29.4) | 47(30.9) |  |
 Other, n (%) | 105(2.3) | 27(1.9) | 15(1.4) | 52(2.9) | 11(7.2) |  |
 Undetermined, n (%) | 159(3.6) | 39(2.7) | 93(8.5) | 24(1.3) | 3(2.0) |  |
Tertiary hospital | 9239 (92.6) | 4180 (87.0) | 2444 (95.8) | 2024 (100.0) | 591 (100.0) | < 0.001 |