Table 2 Pharmacotherapy of acute ischemic stroke in hospital by regions
From: Geographic differences in pharmacotherapy patterns and outcomes of acute ischemic stroke in China
|  | All (N = 9973) | East (N = 4806) | Northeast (N = 2552) | Central (N = 2024) | West (N = 591) | P |
|---|---|---|---|---|---|---|
IVT | 429 (4.3) | 147 (3.1) | 205 (8.0) | 53 (2.6) | 24 (4.1) | < 0.001 |
 rt-PA | 363 (3.6) | 126 (2.6) | 175 (6.9) | 44 (2.2) | 18 (3.0) | < 0.001 |
 Urokinase | 66 (0.7) | 21 (0.4) | 30 (1.2) | 9 (0.4) | 6 (1.0) | 0.001 |
Antiplatelet agents | 9363 (93.9) | 4597 (95.7) | 2324 (91.1) | 1874 (92.6) | 568 (96.1) | < 0.001 |
 Aspirin | 8186 (82.1) | 3956 (82.3) | 2024 (79.3) | 1666 (82.3) | 540 (91.4) | < 0.001 |
 Clopidogrel | 6106 (61.2) | 3170 (66.0) | 1345 (52.7) | 1260 (62.2) | 331 (56.0) | < 0.001 |
 Cilostazol | 83 (0.8) | 63 (1.3) | 16 (0.6) | 3 (0.1) | 1 (0.2) | < 0.001 |
 Tirofiban | 50 (0.5) | 12 (0.2) | 19 (0.7) | 17 (0.8) | 2 (0.3) | 0.003 |
 Ticagrelor | 7 (0.07) | 4 (0.08) | 1 (0.04) | 1 (0.05) | 1 (0.2) | 0.70 |
Anticoagulants | 1063 (10.7) | 480 (10.0) | 221 (8.7) | 311 (15.4) | 51 (8.6) | < 0.001 |
 Heparin | 149 (1.5) | 48 (1.0) | 22 (0.9) | 76 (3.8) | 3 (0.5) | < 0.001 |
 LMWH | 713 (7.1) | 333 (6.9) | 151 (5.9) | 207 (10.2) | 22 (3.7) | < 0.001 |
 Warfarin | 184 (1.8) | 102 (2.1) | 11 (0.4) | 40 (2.0) | 31 (5.2) | < 0.001 |
 NOAC | 102 (1.0) | 52 (1.1) | 42 (1.6) | 7 (0.3) | 1 (0.2) | < 0.001 |
 Fondaparinux sodium | 2 (0.02) | 0 (0.0) | 1 (0.04) | 1 (0.05) | 0 (0.0) | 0.33 |
Statin | 6828 (68.5) | 3502 (72.9) | 1602 (62.8) | 1372 (67.8) | 352 (59.6) | < 0.001 |
Human urinary kallidinogenase | 5112 (51.2) | 2374 (49.4) | 1761 (69.0) | 908 (44.9) | 68 (11.5) | < 0.001 |