Table 3 Association of pharmacotherapy for acute ischemic stroke and hospital regions

IVT

 East

Ref.

Ref.

 Northeast

< 0.001

2.77 (2.23–3.44)

< 0.001

3.17 (2.53–3.99)

 Central

0.33

0.85 (0.62–1.17)

0.52

0.90 (0.65–1.25)

 West

0.19

1.34 (0.86–2.08)

0.15

1.39 (0.89–2.18)

Antiplatelet agents

 East

Ref.

Ref.

 Northeast

< 0.001

0.46 (0.38–0.56)

< 0.001

0.46 (0.38–0.57)

 Central

< 0.001

0.57 (0.46–0.71)

< 0.001

0.55 (0.44–0.69)

 West

0.61

1.12 (0.72–1.74)

0.62

1.12 (0.72–1.75)

Anticoagulants

 East

Ref.

Ref.

 Northeast

0.07

0.85 (0.72–1.01)

0.004

0.77 (0.64–0.92)

 Central

< 0.001

1.64 (1.40–1.91)

< 0.001

1.63 (1.38–1.92)

 West

0.30

0.85 (0.63–1.15)

0.21

0.82 (0.60–1.12)

Statin

 East

Ref.

Ref.

 Northeast

< 0.001

0.63 (0.57–0.70)

< 0.001

0.60 (0.54–0.67)

 Central

< 0.001

0.78 (0.70–0.88)

< 0.001

0.73 (0.65–0.82)

 West

< 0.001

0.55 (0.46–0.65)

< 0.001

0.51 (0.43–0.61)

Human urinary kallidinogenase

 East

Ref.

Ref.

 Northeast

< 0.001

2.28 (2.06–2.52)

< 0.001

2.30 (2.07–2.56)

 Central

0.001

0.83 (0.75–0.93)

< 0.001

0.76 (0.68–0.84)

 West

< 0.001

0.13 (0.10–0.17)

< 0.001

0.12 (0.09–0.15)