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Table 1 Baseline clinical characteristics of all patients and those with and without postoperative delirium

From: Butyrylcholinesterase activity in patients with postoperative delirium after cardiothoracic surgery or percutaneous valve replacement- an observational interdisciplinary cohort study

 

Total (n = 237)

POD (n = 94)

No POD (n = 143)

P- value

Female Sex

89 (37.6%)

36 (38.3%)

53 (37.1%)

.848

Age (years)

74 (64–79.5)

76 (70–81)

71 (62–79)

.001

BMI (kg m−2)

26.9 (24.1–30.1)

26.6 (24–29.8)

27.1 (24.2–30.1)

.541

Type 2 diabetes mellitus

65 (27.4%)

33 (35.1%)

32 (22.4%)

.032

Coronary heart disease

206 (86.9%)

89 (94.7%)

117 (81.8%)

.004

Heart failure

130 (54.9%)

59 (62.8%)

71 (49.7%)

.047

NYHA

   

.011

 0-I

115 (48.5%)

36 (38.3%)

79 (55.2%)

 

 II-IV

122 (51.5%)

58 (61.7%)

64 (44.8%)

 

Arterial hypertension

51 (21.5%)

24 (25.5%)

27 (18.9%)

.223

History of myocardial Infarction

35 (14.8%)

18 (19.1%)

17 (11.9%)

.123

History of atrial fibrillation

67 (28.3%)

24 (25.6%)

43 (30.0%)

.448

History of chronic alcoholism

19 (8.0%)

7 (7.4%)

12 (8.4%)

.793

History of stroke

24 (10.1%)

13 (13.8%)

11 (7.7%)

.125

History of delirium

15 (6.3%)

9 (9.6%)

6 (4.2%)

.096

History of surgery < 6 months

18 (7.6%)

10 (10.6%)

8 (5.6%)

.152

History of depression

18 (7.6%)

6 (6.4%)

12 (8.4%)

.569

History of malignoma

29 (12.2%)

17 (18.1%)

12 (8.4%)

.026

MoCA-score preoperative

25 (22–26)

23 (21–26)

25 (23–27)

 < .001

PHQ-2

   

.322

 0

155 (65.4%)

59 (62.8%)

96 (67.1%)

 

 1

36 (15.2%)

13 (13.8%)

23 (16.1%)

 

 2

27 (11.4%)

12 (12.8%)

15 (10.5%)

 

 3

8 (3.4%)

2 (2.1%)

6 (4.2%)

 

 4

11 (4.6%)

8 (8.5%)

3 (2.1%)

 

MST ≥ 3 points

11 (4.6%)

5 (5.3%)

6 (4.2%)

.688

BChE activity preoperative (U l−1)

2741.1 (2139.7–3286.9)

2558.5 (2007.7–3148.7)

2867 (2249.2–3432.7)

.044

TAVI/MitraClip

41 (17.3%)

11 (11.7%)

30 (21%)

.065

Valve-surgery + CPB

58 (24.5%)

18 (19.1%)

40 (42.6%)

.122

Bypass-surgery + CPB

76 (32.1%)

28 (29.8%)

48 (33.6%)

.542

Bypass-surgery (without CPB)

17 (7.1%)

10 (10.6%)

7 (4.9%)

.094

Vascular-aortic surgery

6 (2.5%)

5 (5.3%)

1 (0.7%)

.027

Valve + bypass-surgery

35 (14.8%)

20 (21.3%)

15 (10.5%)

.022

Transapical valve-surgery

4 (1.7%)

2 (2.1%)

2 (1.4%)

.670

  1. Data are presented as median (25 th-75th percentile) or proportions. Baseline parameters were collected and the groups were compared using χ2-tests or Mann–Whitney-U, respectively. Statistically significant results are shown in bold, p < .05 was considered significant
  2. BMI Body Mass Index, NYHA New York Heart Association, MoCA Montreal Cognitive Assessment, PHQ-2 Patient Health Questionnaire-2, MST Malnutrition Screening Tool, BChE Butyrlycholinesterase, TAVI Transcatheter Aortic Valve Implantation, CPB Cardiopulmonary Bypass
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