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Table 2 Peri- and postoperative variables for patients with and without POD

From: Butyrylcholinesterase activity in patients with postoperative delirium after cardiothoracic surgery or percutaneous valve replacement- an observational interdisciplinary cohort study

 

POD (n = 94 pat.)

No POD (n = 143 pat.)

P- value

Perioperative variables

 Length of surgery (min)

196 (160–246)

182 (128–225)

.028

 Type of anaesthesia

  

.068

 General anaesthetic

85 (90.4%)

117 (81.8%)

 

 Analgosedation

9 (9.6%)

26 (18.2%)

 

 Use of CPB

69 (73.4%)

99 (69.2%)

.489

 Time on CPB (min)

109 (83–137)

102 (80–134)

.355

 Cross-clamped aorta

68 (72.3%)

96 (67.1%)

.396

 Cross-clamp-time (min)

65 (44–79)

60 (46–80)

.435

 MAP (mean)

67 ± 5

68 ± 5

.318

 RCCs intraoperatively

38 (40.4%)

26 (18.2%)

 < .001

 RCCs total

75 (79.8%)

66 (46.2%)

 < .001

 FFPs intraoperatively

6 (6.4%)

5 (3.5%)

.281

 FFPs total

21 (22.3%)

16 (11.2%)

.018

Postoperative variables

 CRP (mg l−1)

174.4 (125.2–243.8)

160.9 (84–211.5)

.022

 Leukocytes (*1000 µl−1)

13.5 (10.3–17.5)

11.8 (9.7–15.3)

.072

 Lactate (mmol l−1)

2.6 (1.9–4.0)

2.1 (1.7–2.6)

 < .001

 Haemoglobine (g dl−1)

8.3 (7.6–8.8)

8.8 (8.2–9.6)

 < .001

 Length of stay (d)

9 (7–12)

8 (7–10)

.008

 Postoperative BChE activity (U l−1)

1463.8 (1217.6–1757.8)

1715.1 (1327.1–2120.8)

.001

 Decline of BChE activity (pre- to postoperative) (%)

39.75 (23.93–53.68)

38.80 (19.60–52)

.327

  1. Data are presented as median (25th-75th percentile) or proportions. Intra- and postoperative parameters were collected and the groups were compared using χ2-tests or Mann–Whitney-U test, respectively. Statistically significant results are shown in bold, p < .05 was considered significant
  2. POD Postoperative Delirium, CPB Cardiopulmonary bypass, MAP Mean arterial pressure, RCC Red-cell concentrate, FFP Fresh frozen plasma, CRP C-reactive Protein, BChE Butyrylcholinesterase