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Table 1 The baseline characteristics of participants

From: Relationship between glycated hemoglobin levels and three-month outcomes in acute ischemic stroke patients with or without diabetes: a prospective Korean cohort study

HbA1c

Non-DM

P-value

DM

P-value

HbA1c (< 5.5%)

HbA1c (5.5%-6.0%)

HbA1c (6.0%-6.5%)

HbA1c (< 6.0%)

HbA1c (6.0%-6.5%)

HbA1c (6.5%-7.0%)

HbA1c (≥ 7.0%)

Participants

158

502

236

 

60

90

181

297

 

Gender

   

0.232

    

0.073

 Male

94 (59.5%)

322 (64.1%)

137 (58.1%)

 

42 (70.0%)

44 (48.9%)

109 (60.2%)

177 (59.6%)

 

 Female

64 (40.5%)

180 (35.9%)

99 (41.9%)

 

18 (30.0%)

46 (51.1%)

72 (39.8%)

120 (40.4%)

 

Age(years)

   

 < 0.001

    

0.354

 < 60

80 (50.6%)

121 (24.1%)

44 (18.6%)

 

12 (20.0%)

16 (17.8%)

26 (14.4%)

64 (21.5%)

 

 60 to < 70

26 (16.5%)

140 (27.9%)

60 (25.4%)

 

14 (23.3%)

25 (27.8%)

51 (28.2%)

92 (31.0%)

 

 70 to < 80

38 (24.1%)

161 (32.1%)

89 (37.7%)

 

23 (38.3%)

30 (33.3%)

75 (41.4%)

104 (35.0%)

 

 ≥ 80

14 (8.9%)

80 (15.9%)

43 (18.2%)

 

11 (18.3%)

19 (21.1%)

29 (16.0%)

37 (12.5%)

 

BMI (kg/m2)

22.8 ± 3.1

23.5 ± 3.0

23.5 ± 3.2

0.034

22.6 ± 3.2

23.1 ± 2.9

23.9 ± 3.2

24.4 ± 3.5

< 0.001

Smoking status

   

0.772

    

0.330

 No

93 (58.9%)

302 (60.2%)

147 (62.3%)

 

34 (56.7%)

61 (67.8%)

115 (63.5%)

174 (58.6%)

 

 Yes

65 (41.1%)

200 (39.8%)

89 (37.7%)

 

26 (43.3%)

29 (32.2%)

66 (36.5%)

123 (41.4%)

 

NIHSS score

3 (1–7)

3(1-)

3 (1–6)

0.937

4.5 (0–23)

4 (0–28)

3 (0–25)

4 (0–30)

0.358

Hypertension

   

0.009

    

0.001

 No

86 (54.4%)

214 (42.6%)

93 (39.4%)

 

6 (10.0%)

12 (13.3%)

50 (27.6%)

83 (27.9%)

 

 Yes

72 (45.6%)

288 (57.4%)

143 (60.6%)

 

54 (90.0%)

78 (86.7%)

131 (72.4%)

214 (72.1%)

 

CHD

   

0.453

    

0.226

 No

146 (92.4%)

453 (90.2%)

209 (88.6%)

 

47 (78.3%)

80 (88.9%)

150 (82.9%)

257 (86.5%)

 

 Yes

12 (7.6%)

49 (9.8%)

27 (11.4%)

 

13 (21.7%)

10 (11.1%)

31 (17.1%)

40 (13.5%)

 

Previous stroke/TIA

   

0.249

    

0.336

 No

134 (84.8%)

412 (82.1%)

185 (78.4%)

 

45 (75.0%)

63 (70.0%)

137 (75.7%)

235 (79.1%)

 

 Yes

24 (15.2%)

90 (17.9%)

51 (21.6%)

 

15 (25.0%)

27 (30.0%)

44 (24.3%)

62 (20.9%)

 

Stroke etiology

   

0.179

    

0.405

 SVO

38 (24.1%)

145 (28.9%)

67 (28.4%)

 

17 (28.3%)

32 (35.6%)

67 (37.0%)

121 (40.7%)

 

 LAA

27 (17.1%)

93 (18.5%)

43 (18.2%)

 

11 (18.3%)

17 (18.9%)

44 (24.3%)

70 (23.6%)

 

 CE

41 (25.9%)

139 (27.7%)

78 (33.1%)

 

19 (31.7%)

24 (26.7%)

39 (21.5%)

50 (16.8%)

 

 Other determined

23 (14.6%)

47 (9.4%)

24 (10.2%)

 

4 (6.7%)

7 (7.8%)

8 (4.4%)

19 (6.4%)

 

 Undetermined

29 (18.4%)

78 (15.5%)

24 (10.2%)

 

9 (15.0%)

10 (11.1%)

23 (12.7%)

37 (12.5%)

 

Death

   

0.973

    

0.373

 No

152 (96.2%)

481 (95.8%)

226 (95.8%)

 

56 (93.3%)

88 (97.8%)

171 (94.5%)

287 (96.6%)

 

 Yes

6 (3.8%)

21 (4.2%)

10 (4.2%)

 

4 (6.7%)

2 (2.2%)

10 (5.5%)

10 (3.4%)

 

TC (mg/dL)

182.2 ± 38.1

184.3 ± 44.2

185.5 ± 44.6

0.757

164.7 ± 43.7

166.3 ± 37.6

174.1 ± 42.2

179.2 ± 49.1

0.031

TG (mg/dL)

107.2 ± 60.3

106.3 ± 49.7

112.1 ± 56.4

0.379

99.0 ± 51.7

121.0 ± 64.8

118.3 ± 58.3

129.4 ± 67.5

0.006

HDL-C(mg/dL)

47.8 ± 14.8

47.8 ± 13.9

47.3 ± 14.0

0.898

48.0 ± 15.1

44.9 ± 15.7

44.0 ± 12.5

42.9 ± 13.0

0.058

LDL-C (mg/dL)

107.9 ± 33.9

112.2 ± 37.9

114.1 ± 39.9

0.274

95.8 ± 39.5

94.9 ± 30.1

104.0 ± 35.8

106.2 ± 40.3

0.036

ALB (g/dL)

4.1 ± 0.4

4.1 ± 0.4

4.0 ± 0.4

0.098

3.9 ± 0.4

4.0 ± 0.5

4.0 ± 0.4

4.0 ± 0.5

0.332

Scr (mg/dL)

0.9 ± 0.6

1.0 ± 0.9

1.0 ± 0.4

0.740

2.1 ± 2.4

1.3 ± 1.3

1.2 ± 1.2

1.1 ± 1.0

< 0.001

HGB (g/dL)

13.8 ± 2.1

13.8 ± 1.8

13.5 ± 1.9

0.083

12.6 ± 1.9

12.6 ± 2.3

13.4 ± 1.9

13.5 ± 2.0

< 0.001

C-reactive protein (mg/dL)

0.9 ± 2.7

0.8 ± 2.1

1.2 ± 3.3

0.224

1.7 ± 3.0

0.8 ± 2.5

1.1 ± 3.1

1.4 ± 3.9

0.306

HbA1c (%)

5.3 ± 0.2

5.7 ± 0.1

6.2 ± 0.1

 < 0.001

5.7 ± 0.2

6.2 ± 0.1

6.7 ± 0.1

8.3 ± 1.2

< 0.001

  1. Values are n (%) or mean ± SD or median (quartile)
  2. DM Diabetes mellitus, HGB Hemoglobin concentration, BMI Body mass index, TC Total cholesterol, TG Triglyceride, LDL-C Low-density lipoproteins cholesterol, HDL-C High-density lipoprotein cholesterol, Scr Serum creatinine, ALB Serum albumin, BMI Body mass index, CHD Coronary heart disease, HbA1c Glycated hemoglobin, TIA Transient ischemia attack, NIHSS National institute of health stroke scale, SVO Small vessel occlusion, LAA Small vessel occlusion, CE Cardio embolism