Relationship between glycated hemoglobin levels and three-month outcomes in acute ischemic stroke patients with or without diabetes: a prospective Korean cohort study

Table 4 The results of a two-piecewise binary logistic regression model

3-month adverse clinical outcomes	All participants (OR,95%CI, P)	Non-DM (OR,95%CI, P)	DM (OR,95%CI, P)
Fitting model by standard linear regression (per 1% increase for HbA1c)	1.12 (0.97, 1.30) 0.129	1.68 (0.92, 3.07) 0.092	1.14 (0.97, 1.35) 0.118
Fitting model by two-piecewise binary logistic regression
Inflection point of HbA1c (%)	8.2	5.4	6.1
≤ Inflection point (per 1% increase for HbA1c)	0.98 (0.76, 1.26) 0.866	0.69 (0.06, 7.96) 0.766	0.13 (0.02, 0.81) 0.029
> Inflection point (per 1% increase for HbA1c)	1.33 (0.99, 1.79) 0.060	1.942 (0.94, 4.0) 0.072	1.23 (1.03, 1.47) 0.021
P for log-likelihood ratio test	0.197	0.476	0.018

Note 1: In all participants, we adjusted age, smoking status, sex, TG, BMI, HGB, HDL-C, ALB, C-reactive protein, LDL-C, Scr, previous stroke or TIA, CHD, DM, hypertension, and NIHSS score
Note 2: For DM and Non-DM subgroups, we adjusted for age, smoking status, sex, TG, BMI, HGB, HDL-C, ALB, C-reactive protein, LDL-C, Scr, previous stroke or TIA, CHD, hypertension, stroke etiology, and NIHSS score
HbA1c Glycated hemoglobin, OR Odds ratios, CI Confidence, DM Diabetes mellitus

ISSN: 1471-2377