Table 5 Relationship between HbA1c and 3-month adverse clinical outcomes in AIS patients with and without diabetes analyzed by two-piecewise binary logistic regression model in different sensitivity analyses
3-month adverse clinical outcomes | Non-DM (OR,95%CI, P) | DM (OR,95%CI, P) | Total (OR,95%CI, P) |
|---|---|---|---|
Model 4 | |||
 Fitting model by two-piecewise binary logistic regression | |||
  Inflection point of HbA1c (%) | 5.9 | 5.9 | 8.3 |
  ≤ Inflection point (per 1% increase for HbA1c) | 1.33 (0.51, 3.50) 0.559 | 0.02 (0.00, 0.73) 0.032 | 0.99 (0.76, 1.30) 0.943 |
  > Inflection point (per 1% increase for HbA1c) | 3.36 (0.64, 17.77) 0.154 | 1.22 (1.02, 1.46) 0.032 | 1.36 (0.98, 1.87) 0.063 |
 P for log-likelihood ratio test | 0.425 | 0.018 | 0.217 |
Model 5 | |||
 Fitting model by two-piecewise binary logistic regression | |||
  Inflection point of HbA1c (%) | 5.7 | 6.0 | 8.3 |
  ≤ Inflection point (per 1% increase for HbA1c) | 4.26 (0.68, 26.66) 0.122 | 0.02 (0.00, 0.48) 0.015 | 0.89 (0.64, 1.23) 0.481 |
  > Inflection point (per 1% increase for HbA1c) | 1.490 (0.381, 5.833) 0.5665 | 1.24 (0.99, 1.55) 0.058 | 1.61 (1.09, 2.37) 0.016 |
 P for log-likelihood ratio test | 0.447 | 0.007 | 0.050 |