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Table 1 Baseline characteristics of the patients

From: Clopidogrel with indobufen or aspirin in minor ischemic stroke or high-risk transient ischemic attack: a randomized controlled clinical study

Characteristic

Clopidogrel with Aspirin(n = 93)

Clopidogrel with Indobufen(n = 89)

t or χ2

P

Female sex -no. (%)

73 (78.5)

61 (67.8)

χ2 = 2.321

0.128

Age (yr)

60.8 ± 12.3

60.8 ± 11.5

t=-0.006

0.995

 Interquartile range

53–71

52–68

  

BMI (kg/m2)

24.7 ± 3.15

25.6 ± 2.64

t = 1.915

0.060

Systolic pressure (mmHg)

146 ± 21

144 ± 18

t = 0.833

0.407

 Interquartile range

132–160

132–154

  

Diastolic pressure (mmHg)

88 ± 14

91 ± 13

t=-1.370

0.174

 Interquartile range

80–98

80–101

  

Medical history -no. (%)

    

 Hypertension

60 (64.5)

62 (69.7)

χ2 = 0.545

0.460

 Coronary heart disease

5 (5.4)

4 (4.5)

-

1.000

 Hypercholesterolemia

3 (3.2)

4 (4.5)

-

0.716

 Diabetes mellitus

16 (17.2)

12 (13.5)

χ2 = 0.484

0.487

 Arrhythmia

0 (0)

0 (0)

-

-

Current or previous smoking - no. (%)

51 (54.8)

43 (48.3)

χ2 = 0.775

0.379

Current or previous alcohol - no. (%)

32 (34.4)

31 (34.8)

χ2 = 0.004

0.952

TIA

4 (4.3)

4 (4.4)

χ2 = 0.002

0.962

ABCD2 Score

4

4.25

  

Minor stroke

89

85

-

1.000

TOAST -no. (%)

    

 Large-artery Atherosclerosis (LAA)

38 (42.7)

26 (30.6)

χ2 = 2.741

0.098

 Small-Artery Occlusion (SAO)

46 (51.2)

53 (62.3)

χ2 = 2.017

0.156

 Stroke of Other Determined Causes (SOE)

1 (1.1)

0 (0)

-

1.000

 Stroke of Undetermined Etiology (SUE)

4 (4.5)

6 (7.0)

χ2 = 0.161

0.689

WBC (×109/L)

7.84 ± 2.43

7.5 ± 2.38

t = 0.902

0.370

ESR (mm/H)

15.8 ± 13.88

13.1 ± 14.83

t = 0.752

0.458

CRP (mg/L)

4.28 ± 5.80

3.84 ± 7.25

t = 0.374

0.710

TG (mmol/l)

1.96 ± 1.56

1.86 ± 1.10

t = 0.468

0.641

TC (mmol/l)

5.11 ± 1.44

4.95 ± 1.01

t = 0.926

0.357

HDL-C (mmol/l)

1.09 ± 0.32

1.18 ± 0.47

t=-1.415

0.161

LDL-C (mmol/l)

3.13 ± 1.01

3.03 ± 0.96

t = 0.855

0.395

FIB

3.13 ± 0.85

3.05 ± 0.81

t = 0.697

0.488

GLU (mmol/l)

6.42 ± 2.87

6.21 ± 2.60

t = 0.453

0.652

HbA1c (%)

6.51 ± 1.57

6.55 ± 1.54

t=-0.211

0.833

tHcy (mmol/l)

15.89 ± 12.34

13.60 ± 4.05

t = 1.630

0.107

  1. Abbreviation: TOAST classification, Trial of Org 10,172 in Acute Stroke Treatment; WBC, White Blood Cell Count; ESR, Erythrocyte Sedimentation Rate; CRP, C-reactive Protein; TG, Triglyceride; HDL-C, High Density Lipoprotein Cholesterol; LDL-C, Low Density Lipoprotein Cholesterol, FIB, Fibrinogen; GLU, Glucose; HbA1c, Glycosylated Hemoglobin, Type A1C; tHcy, Total Homocysteine