Table 1 Summary of patients with sporadic human prion disease
Patient number | 1 | 2 | 3 |
|---|---|---|---|
Sex | Female | Female | Male |
Age at onset (years) | 69 | 74 | 73 |
Time from onset till death (months) | 27 | 4 | 16 |
sCJD subtype based on Parchi’s classification | MM1 | MM1 | MM1 |
log SD50/g tissue in brains homogenates based on the RT-QuIC assay (mean ± SD) | 10.38 ± 0.18 | 10.25 ± 0.35 | 10.00 ± 0.00 |
log SD50/g tissue in brains homogenates based on the second generation QuIC assay (mean ± SD) | 10.50 ± 0.50 | 10.75 ± 1.15 | 10.60 ± 1.25 |
log SD50/g tissue in brains homogenates based on the eQuIC assay (mean ± SD) | 12.75 ± 0.35 | 12.25 ± 0.18 | 12.50 ± 0.35 |