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Table 4 Comparison of variables between the VCI and NCF groups in patients with mWMH

From: The associations between peripheral inflammatory and lipid parameters, white matter hyperintensity, and cognitive function in patients with non-disabling ischemic cerebrovascular events

Characteristics

VCI (n = 54)

NCF (n = 92)

P value

Cohen’s d

Age (years)

61.26(57.00,66.00)

59.87(43.50,69.00)

0.413

0.143

BMI (kg/m2)

24.75 ± 3.44

24.78 ± 3.65

0.963

0.008

Gender, male, n (%)

23(42.6%)

62(67.4%)

0.301

 

Hypertension, n (%)

37(68.5%)

59(64.11%)

0.719

 

Diabetes, n (%)

14(25.9%)

28(30.4%)

0.695

 

Smoking, n (%)

23(42.6%)

45(48.9%)

0.669

 

Alcoholism, n (%)

19(35.1%)

29(31.5%)

0.614

 

Lymphocyte (* 109/L)

1.72 ± 0.56

2.09 ± 0.66

< 0.001

0.591

Neutrophil (* 109/L)

3.46(2.44,4.00)

4.00(2.80,4.84)

0.025

0.349

Platelet (* 109/L)

211.20 ± 45.51

216.85 ± 58.47

0.393

0.267

NLR

2.17(1.57,2.82)

2.02(1.51,2.59)

0.104

0.200

PLR

131.67 ± 57.09

110.47 ± 34.6

0.035

0.467

WBC (* 109/L)

6.24(5.11,7.05)

6.68(5.23,7.58)

0.081

0.283

MLR

0.30(0.23,0.34)

0.26(0.21,0.32)

0.022

0.366

SII

482.81(267.15,565.65)

424.92(297.60,568.54)

0.331

0.117

SIRI

1.08(0.61,1.27)

1.07(0.64,1.35)

0.650

0.012

TG (mmol/L)

1.54(0.86,1.90)

1.86(1.06,2.13)

0.111

0.257

TC (mmol/L)

6.22(3.56,4.81)

4.69(3.93,5.28)

0.007

0.178

HDL-C (mmol/L)

1.33(1.02,2.03)

2.92(0.98,1.64)

0.696

0.125

LDL-C (mmol/L)

2.35 ± 0.81

2.81 ± 0.91

0.007

0.514

LDL-C/HDL-C

1.94 ± 0.83

2.41 ± 1.02

0.009

0.507

Fasting glucose (mmol/L)

5.04(4.64,5.75)

4.95(4.72,5.75)

0.403

0.062

lipoprotein(a)

212.63(96.50,328.00)

202.90 (66.50,251.00)

0.171

0.062

  1. Abbreviations: WMH, White matter hyperintensities; BMI, body mass index; NLR, neutrophil-to-lymphocyte ratio; PLR platelet-to-lymphocyte ratio; WBC, white blood cells; MLR monocyte -to-lymphocyte ratio, SII systemic immune-inflammation index; SIRI systemic inflammation response index; TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; MoCA, Montreal Cognitive Assessment; AVLT, Auditory Verbal Learning Test; SDMT, Symbol Digit Modalities Test; SCWT, Stroop Color-Word Test; DST, Digit Span Test