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Table 2 Study assessments and registrations

From: Exploring vascular contributions to cognitive impairment and dementia (ENIGMA): protocol for a prospective observational study

Assessment/registration

Baseline

3-month follow-up

12-month follow-up

Long-term follow-up

Demographics

x

   

Medical history

x

   

Medication use

x

   

Admission NIHSS score

x

   

Symptom onset and admission time

x

   

Acute treatment

x

   

Standard blood chemistry at admission

x

   

Pre-stroke mRS

x

   

IQCODE

x

   

Height, weight and BP

x

x

x

 

Smoking and alcohol use

x

   

MoCA

x

x

x

 

PASE

x

x

x

 

WHO-5

x

x

x

 

MDI

x

x

x

 

Educational level

x

   

New vascular events

 

x

x

x

Functional outcome: mRS

 

x

x

 

Stroke classification: TOAST and OSCP

 

x

  

RBANS

 

x

x

 

Blood sample for EVs*

x

x

  

Blood sample for APOE genotyping

 

x

  

MRI**

x

 

x

 

Dementia

   

x

  1. *Blood sample for EVs is drawn 24 h (+/- 8 h) after admission
  2. **Baseline MRI is performed 24 h (+/- 6 h) after acute MRI on admission
  3. NIHSS: National Institutes of Health Stroke Scale, mRS: modified Rankin scale, IQCODE: Informant Questionnaire on Cognitive Decline in the Elderly, BP: blood pressure, MoCA: Montreal Cognitive Assessment, PASE: Physical Activity Scale for the Elderly, WHO-5: World Health Organisation Five Well-Being Index, MDI: Major Depression Inventory, TOAST: trial of Org 10,172 in Acute Stroke Treatment, OSCP: Oxfordshire Community Stroke Project Classification, RBANS: Repeatable Battery for the Assessment of Neuropsychological Status, EVs: extracellular vesicles, APOE: apolipoprotein E, MRI: magnetic resonance imaging