Fig. 3

Correlations of neurodegenerative and glial activation markers with CSF Aβ₄₂ and CSF p-tau₁₈₁ in the overall study population and in genotype groups. A CSF neurofilament light chain (NfL) (higher levels index more neuroaxonal injury). B CSF neurogranin (Ng) (higher levels index more synaptic injury). C CSF YKL-40 (higher levels index more glial activation). Simple linear correlation analyses: R square and P value were obtained by fitting a simple linear regression model. Only those analytes associated with either CSF Aβ₄₂ or CSF p-tau₁₈₁ in multiple regression analyses are shown