Intrathecal baclofen efficacy for managing motor function and spasticity severity in patients with cerebral palsy: a systematic review and meta-analysis

Table 4 ITB Complications

System	Major Side Effects	Minor Side Effects	References
Immune System	Infections, Meningitis		[26, 68, 70, 73, 76, 77, 79,80,81, 84, 86]
Nervous system	Seizures, Cerebrospinal fluid leaks	Drowsiness, Sleepiness, Headache, Increased oral secretions, Lethargy	[25, 26, 68, 72, 76,77,78,79,80, 84,85,86]
Cognitive system	Hallucinations, Agitation, Depression, Irritability, Other psychiatric side effects		[25, 73, 80, 81]
Cardiovascular system	Hypotension, Bradycardia, Fainting	Edema of ankles, feet, or upper libs, Hypothermia	[26, 67, 72, 81, 85]
Respiratory system	Respiratory depression, Apnea		[81]
Gastrointestinal system	Nausea/vomiting	Constipation, Reflux	[26, 72, 76,77,78]
Urinary system	Urinary retention	Dysuria, Cystitis	[26, 72, 76, 85]
Skin	Cutaneous hematoma, Seroma	Skin reactions, Pressure sore, Wound dehiscence, Pruritus	[25, 26, 68,69,70, 72, 74, 76, 77, 79, 85]
Muscular system	Progression of scoliosis	Decreased balance, Flaccidity, Jumpy legs	[25, 68, 72, 78, 81]

ISSN: 1471-2377