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Figure 2 | BMC Neurology

Figure 2

From: CMV-associated encephalitis and antineuronal autoantibodies - a case report

Figure 2

(A,B) Percentages of CD4 + T cells producing IFN-γ in response to CMV immediate early (IE) antigen-1 and pp65 in the patient (A) and 7 CMV-seropositive donors (B). S. aureus enterotoxin B (SEB) served as positive control. PBMC; peripheral blood mononuclear cells. (C,D) Enumeration of DC subsets in the patient (C) and 13 donors (D). BDCA; blood dendritic cell antigen. (E-H) Neuroimmunological findings. (E,G) Hippocampal neurons (granular [Gr] and pyramidal [Pyr] cell layers) after immunostaining with patient serum (green, 1:25,000) (E) or serum from control (1:5,000) (G). (F, H) Double-labeling with patient serum (green) and GAD (red). Arrows and inset indicate double-labelled cells. Arrowhead; GAD-positive serum-negative cell.

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