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Table 5 Mean difference in change from baseline in seizure-free days over the last 28 days for pregabalin versus gabapentin from the indirect comparison using placebo as the common comparator

From: Pregabalin versus gabapentin in partial epilepsy: a meta-analysis of dose-response relationships

Dose Comparison

Mean Difference

95% CI

150 mg vs. 900 mg

0.97

0.25, 1.69

300 mg vs. 1200 mg

1.24

0.46, 2.02

450 mga vs. 1800 mg

1.35

0.52, 2.18

600 mg vs. 1800 mg

1.48

0.62, 2.34

600 mg vs. 2400 mga

1.42

0.55, 2.29

  1. a450 mg pregabalin and 2400 mg gabapentin were not studied, thus, these results were calculated from the dose-response equation.
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BMC Neurology

ISSN: 1471-2377

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