Articles

First report of Bickerstaff’s brainstem encephalitis caused by Salmonella Dublin: a case report

Diseases caused by nontyphoid Salmonella can range from mild, to self-limiting gastroenteritis and severe invasive infection. Relatively rarely, Salmonella may cause severe encephalopathy.

Authors: Jiangbo Xie, Tingting Zhang and Tao Liu

Endovascular treatment of vertebral and basilar artery aneurysms with low-profile visualized intraluminal support device

The Low-profile Visualized Intraluminal Support (LVIS) device is a self-expanding, nitinol, single-braid, closed-cell device that was recently developed for endovascular embolization of intracranial aneurysms....

Authors: Quanlong Hong, Wenqiang Li, Jing Ma, Peng Jiang and Yisen Zhang

Identification of upregulated NF-κB inhibitor alpha and IRAK3 targeting lncRNA following intracranial aneurysm rupture-induced subarachnoid hemorrhage

This study was performed to identify genes and lncRNAs involved in the pathogenesis of subarachnoid hemorrhage (SAH) from ruptured intracranial aneurysm (RIA).

Authors: Wei Leng, Dan Fan, Zhong Ren and Qiaoying Li

Time course of outcome in poor grade subarachnoid hemorrhage patients: a longitudinal retrospective study

Neurological outcome and mortality of patients suffering from poor grade subarachnoid hemorrhage (SAH) may have changed over time. Several factors, including patients’ characteristics, the presence of hydrocep...

Authors: Elisa Gouvêa Bogossian, Daniela Diaferia, Andrea Minini, Narcisse Ndieugnou Djangang, Marco Menozzi, Lorenzo Peluso, Filippo Annoni, Jacques Creteur, Sophie Schuind, Olivier Dewitte and Fabio Silvio Taccone

BRAF^non-V600E more frequently co-occurs with IDH1/2 mutations in adult patients with gliomas than in patients harboring BRAF^V600E but without a survival advantage

The effects of BRAF^non-V600E and BRAF^V600E on the outcomes and the molecular characteristics of adult glioma patients are unknown and need to be explored, although BRAF^V600E has been extensively studied in pediat...

Authors: Wei Wang, Maode Wang, Haitao Jiang, Tuo Wang and Rong Da

Prevalence and profile of nocturnal disturbances in Chinese patients with advanced-stage Parkinson’s disease: a cross-sectional epidemiology study

The impact of nocturnal disturbance (ND) in Parkinson’s disease on quality of life of patients in Western Countries is increasingly understood. Our study aimed to investigate ND prevalence and its quality of l...

Authors: Guiying He, Chun-Feng Liu, Qinyong Ye, Zhenguo Liu, Miao Jin, Huifang Shang, Ling Chen, Houzhen Tuo, Hong Jiang, Jifu Cai, Kalpesh Joshi, James Cooper, Lu Zi and Shengdi Chen

Explaining the facilitators of quality of life in patients with multiple sclerosis: a qualitative study

In patients with multiple sclerosis (MS), the disease’s complications and manifestations affect a person’s ability to function normally and leads to further disruptions in their education, family life, job opp...

Authors: Atefeh Homayuni, Sedigheh Abedini, Zahra Hosseini, Masoud Etemadifar and Amin Ghanbarnejad

Correction to: Post-traumatic cerebral fat embolism syndrome with a favourable outcome: a case report

Authors: Wei Wang, Weibi Chen, Yan Zhang, Yingying Su and Yuping Wang

Prognostic value of the neutrophil-to-lymphocyte ratio in acute ischemic stroke patients treated with intravenous thrombolysis: a systematic review and meta-analysis

The relationship between the neutrophil-to-lymphocyte ratio (NLR) and poor prognostics in acute ischemic stroke (AIS) patients who receive intravenous thrombolysis (IVT) remains controversial. The purpose of t...

Authors: Chengbing Wang, Qian Zhang, Mingwei Ji, Jing Mang and Zhongxin Xu

The role of surgical resection in primary central nervous system lymphoma: a single-center retrospective analysis of 70 patients

The aim of this study was to evaluate the effect of surgical resection and stereotactic biopsy on the complication rate, progression-free survival (PFS) and overall survival (OS) of 70 patients diagnosed at a ...

Authors: Shiqiang Wu, Junwen Wang, Weihua Liu, Feng Hu, Kai Zhao, Wei Jiang, Ting Lei and Kai Shu

Agreement between neuroimages and reports for natural language processing-based detection of silent brain infarcts and white matter disease

There are numerous barriers to identifying patients with silent brain infarcts (SBIs) and white matter disease (WMD) in routine clinical care. A natural language processing (NLP) algorithm may identify patient...

Authors: Lester Y. Leung, Sunyang Fu, Patrick H. Luetmer, David F. Kallmes, Neel Madan, Gene Weinstein, Vance T. Lehman, Charlotte H. Rydberg, Jason Nelson, Hongfang Liu and David M. Kent

Ipsilateral hypoperfusion caused by intracerebral steal phenomenon after carotid artery stenting: a case report

Abnormal hypoperfusion on the surgical side after carotid artery stenting is rare. Neurological deterioration caused by it is deceptive, which can easily lead to misdiagnosis. The mechanism of hypoperfusion ha...

Authors: Zhizhong Yan, Zhonghua Shi, Yuhai Wang, Chunlei Zhang, Huize Liu, Jin Cai and Xin Zhang

Study of the collagen type VI alpha 3 (COL6A3) gene in Parkinson’s disease

To date, the genetic contribution to Parkinson’s disease (PD) remains unclear. Mutations in the collagen type VI alpha 3 (COL6A3) gene were recently identified as a cause of isolated dystonia. Since PD and dyston...

Authors: Chong-Yao Jin, Ran Zheng, Zhi-Hao Lin, Nai-Jia Xue, Ying Chen, Ting Gao, Yi-Qun Yan, Yi Fang, Ya-Ping Yan, Xin-Zhen Yin, Jun Tian, Jia-Li Pu and Bao-Rong Zhang

Risk factors related balance disorder for patients with dizziness/vertigo

When dizziness/vertigo patients presented with balance disorder, it will bring severe morbidity. There is currently lack of research to explore risk factor related balance disorder in dizziness patients, espec...

Authors: Zhentang Cao, Cuiting Zhu, Yanan Zhou, Yan Wang, Meimei Chen, Yi Ju and Xingquan Zhao

Morvan syndrome associated with LGI1 antibody: a case report

Morvan syndrome (MoS) is a rare autoimmune syndrome associated with antibodies against two kinds of potassium channel proteins, contactin associated protein-like 2 (CASPR2) and leucine-rich glioma inactivated ...

Authors: Shui-Jing Zhang, Yan-Yan Xue, Hao Yu and Qing-Qing Tao

Headache from clinically confirmed hemicrania continua arising from the sternocleidomastoid muscle: a case report

A patient with a history of cluster headaches, now in remission, presented with confirmed hemicrania continua that resolved with a local anaesthetic injection into the Sternocleidomastoid (SCM) muscle. To the ...

Authors: Osnat Wende and Shira Markowitz

Rituximab and risk of COVID-19 infection and its severity in patients with MS and NMOSD

Choosing a safe disease modifying therapy during the COVID-19 pandemic is challenging. This case series study was conducted to determine the incidence rate and the course of Covid-19 infection in MS/NMOSD pati...

Authors: Sara Esmaeili, Mohammad Hossein Abbasi, Meysam Abolmaali, Mohammad Mojtahed, Seyedeh Niloufar Rafiei Alavi, Sevim Soleimani, Mahisa Mokhtari, Jaber Hatam, Samaneh Tanhapour Khotbehsara, Mohammad Reza Motamed, Mohammad Taghi Joghataei, Zahra Mirzaasgari and Mehdi Moghaddasi

An age-dependent outcome analysis of microvascular decompression and percutaneous thermocoagulation in trigeminal neuralgia

Trigeminal neuralgia (TN) is a severe pain condition and the most common facial neuralgia. While microvascular decompression (MVD) presents an excellent treatment in neurovascular compression cases, percutaneo...

Authors: Naureen Keric, Darius Kalasauskas, Sophia L. Kreth, Martin B. Glaser, Harald Krenzlin, Sven R. Kantelhardt and Florian Ringel

Camptocormia in patients with multiple system atrophy at different disease durations: frequency and related factors

Camptocormia is common in patients with multiple system atrophy (MSA). The current study was aimed at assessing the frequency of camptocormia and its related factors in MSA patients with different disease dura...

Authors: Ling Yu Zhang, Bei Cao, Qian-Qian Wei, Ru Wei Ou, Bi Zhao, Jing Yang, Ying Wu and Hui Fang Shang

Novel manifestations of Warburg micro syndrome type 1 caused by a new splicing variant of RAB3GAP1: a case report

The present study aimed to determine the underlying genetic factors causing the possible Warburg micro syndrome (WARBM) phenotype in two Iranian patients.

Authors: Raziyeh Khalesi, Ehsan Razmara, Golareh Asgaritarghi, Ali Reza Tavasoli, Yasser Riazalhosseini, Daniel Auld and Masoud Garshasbi

Hemisensory syndrome: Hyperacute symptom onset and age differentiates ischemic stroke from other aetiologies

An important cause of hemisensory syndrome is ischemic stroke. However, the diagnostic yield of neuroradiological imaging on hemisensory syndrome is low. Therefore, we aim to describe patients hospitalized wit...

Authors: Pei Xuan Koh, Joanna Ti, Seyed Ehsan Saffari, Zhen Yu Isis Claire Lim and Tianming Tu

Traumatic ischemic injury in a top of the basilar distribution: a case report

Top of the basilar syndrome is a rare, heterogeneous disorder that has previously only been described in the setting of acute ischemic stroke in predominantly elderly patients. We present the first reported ca...

Authors: Mihir Gupta, Anudeep Yekula, David Barba, J. Scott Pannell and Jeffrey Tomlin

Nerve transfer surgery in spinal cord injury: online information sharing

Nerve transfer to improve upper extremity function in persons with cervical spinal cord injury (SCI) is a new reconstructive option, and has led to more people seeking and sharing surgical information and expe...

Authors: Syena Moltaji, Christine B. Novak and Jana Dengler

Effectiveness of paranasal air suction on acute migraine using portable air sucker – a randomized, double blind study

Migraine is a primary headache disorder and is the most common disabling primary headache disorder that occurs in children and adolescents. A recent study showed that paranasal air suction can provide relief t...

Authors: S. M. R. Bandara, S. Samita, A. M. Kiridana and H. M. M. T. B. Herath

Efficacy of galcanezumab in patients with migraine who did not benefit from commonly prescribed preventive treatments

Galcanezumab is a calcitonin gene-related peptide (CGRP) monoclonal antibody (mAb) indicated for the preventive treatment of migraine. While galcanezumab has demonstrated efficacy in patients who did not respo...

Authors: Dulanji K. Kuruppu, Joshua Tobin, Yan Dong, Sheena K. Aurora, Laura Yunes-Medina and A. Laine Green

Effectiveness of medication in cluster headache

The aim of this work is to analyze the reports on cluster headache attacks collected online in the citizen science project CLUE with respect to the effectiveness of drugs taken during the attacks. The collecti...

Authors: Johannes Drescher, Andreas Khouri, Tina Katharina Amann, Charly Gaul, Peter Kropp, Yannic Siebenhaar and Jörg Scheidt

Serial magnetic resonance imaging findings during severe attacks of familial hemiplegic migraine type 2: a case report

Hemiplegic migraines represent a heterogeneous disorder with various presentations. Hemiplegic migraines are classified as sporadic or familial based on the presence of family history, but both subtypes have ...

Authors: David Fear, Misha Patel and Ramin Zand

Performance of Mattis dementia rating scale-Chinese version in patients with mild cognitive impairment and Alzheimer’s disease

To identify the applicability of the Chinese Version of Mattis Dementia Rating Scale (DRS-CV).

Authors: Shuxia Qian, Keliang Chen, Qiaobing Guan and Qihao Guo

Clinical prognosis of isolated anterior cerebral artery territory infarction: a retrospective study

Isolated anterior cerebral artery territory (ACA) infarction is a rare phenomenon, and is known to have distinctive clinical features. Little is known regarding the clinical prognosis of isolated ACA territory...

Authors: Hyungjong Park, Young Seok Jeong, Seo Hyeon Lee, Seong Hwa Jang, Doo Hyuk Kwon, Jeong-Ho Hong, Sung-Il Sohn and Joonsang Yoo

Assessment of cognitive functions in patients with multiple sclerosis applying the normative values of the Rao’s brief repeatable battery in the Portuguese population

The Brief Repeatable Battery of Neuropsychological Tests (BRBN-T) is one of the most sensitive and used measures for detecting cognitive impairment in Multiple Sclerosis (MS).

Authors: Claudia Sousa, Mariana Rigueiro-Neves, Ana Margarida Passos, Aristides Ferreira and Maria José Sá

Aging-associated inflammation and fibrosis in arachnoid membrane

The physiological and pathological significance of the arachnoid membrane (AM) is still unknown. In this study, we investigated various characteristics of the AM, focusing on the influence of inflammation and ...

Authors: Hime Suzuki, Takeshi Mikami, Naotoshi Iwahara, Yukinori Akiyama, Masahiko Wanibuchi, Katsuya Komatsu, Rintaro Yokoyama, Tsukasa Hirano, Ryusuke Hosoda, Yoshiyuki Horio, Atsushi Kuno and Nobuhiro Mikuni

Reduction in circulating vitamin D binding protein in patients with multiple sclerosis

In this study, we aimed to determine the risk association between vitamin D binding protein (VDBP) polymorphism in patients with multiple sclerosis (MS) in a MS biobank and the difference in VDBP serum levels ...

Authors: Zhila Maghbooli, Abolfazl Omidifar, Tarlan Varzandi, Tayebeh Salehnezhad and Mohammad Ali Sahraian

The possible role of Interleukin-6 as a regulator of insulin sensitivity in patients with neuromyelitis optica spectrum disorder

Neuromyelitis optica spectrum disorder (NMOSD) is associated with inflammatory mediators that may also trigger downstream signaling pathways leading to reduce insulin sensitivity.

Authors: Zhila Maghbooli, Abdorreza Naser Moghadasi, Nasim Rezaeimanesh, Abolfazl Omidifar, Tarlan Varzandi and Mohammad Ali Sahraian

Delayed development of aphasia related to degeneration of the arcuate fasciculus in the dominant hemisphere nine years after the onset in a patient with intracerebral hemorrhage: a case report

We report on a patient with an intracerebral hemorrhage (ICH), who showed delayed development of aphasia, which was demonstrated via follow up diffusion tensor tractography (DTT) to be related to neural degene...

Authors: Min Jye Cho and Sung Ho Jang

Sex and onset-age-related features of excessive daytime sleepiness and night-time sleep in patients with Parkinson’s disease

The clinical characteristics of Parkinson’s disease (PD) differ between men and women, and late- and early-onset patients, including motor symptoms and some nonmotor symptoms, such as cognition, anxiety, and d...

Authors: Ming Liu, Ya-Jun Luo, Han-Ying Gu, Yi-Ming Wang, Man-Hua Liu, Kai Li, Jiao Li, Sheng Zhuang, Yun Shen, Hong Jin, Jing Chen, Cheng-Jie Mao and Chun-Feng Liu

Prediction of survival in amyotrophic lateral sclerosis: a nationwide, Danish cohort study

Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease with great heterogeneity. Biological prognostic markers are needed for the patients to plan future supportive treatment, palliative tre...

Authors: Anne-Lene Kjældgaard, Katrine Pilely, Karsten Skovgaard Olsen, Anders Hedegaard Jessen, Anne Øberg Lauritsen, Stephen Wørlich Pedersen, Kirsten Svenstrup, Merete Karlsborg, Helle Thagesen, Morten Blaabjerg, Ásta Theódórsdóttir, Elisabeth Gundtoft Elmo, Anette Torvin Møller, Lone Bonefeld, Mia Berg, Peter Garred…

German translation, cultural adaptation and validation of the unidimensional self-efficacy scale for multiple sclerosis

Self-efficacy concerns individuals’ beliefs in their capability to exercise control in specific situations and complete tasks successfully. In people with multiple sclerosis (PwMS), self-efficacy has been asso...

Authors: Barbara Seebacher, Roger J. Mills, Markus Reindl, Laura Zamarian, Simone Kircher, Christian Brenneis, Rainer Ehling and Florian Deisenhammer

Development of a patient-reported outcome measure for patients who have recovered from a subarachnoid hemorrhage: the “questionnaire for the screening of symptoms in aneurysmal subarachnoid hemorrhage” (SOS-SAH)

Patients who have been successfully treated for an aneurysmal subarachnoid hemorrhage (aSAH) often retain multiple health complaints, including mood disorders, cognitive complaints, fatigue, and problems with ...

Authors: Edith Nobels-Janssen, Inger L. Abma, Wim I. M. Verhagen, Ronald H. M. A. Bartels, Philip J. van der Wees and Jeroen D. Boogaarts

Acute motor and sensory axonal neuropathy in association with primary Sjögren’s syndrome: a case report

Primary Sjögren’s syndrome is a chronic, autoimmune, connective tissue disorder that results from the infiltration of exocrine glands, especially the lacrimal and salivary glands, by autoantibodies. Patients w...

Authors: Yu-Ming Chen and Kuei-Ying Su

The initial CT blend sign is not associated with poor patient outcomes after stereotactic minimally invasive surgery

The initial CT blend sign is an imaging marker that has been used to predict haematoma expansion and poor outcomes in patients with small-volume intracerebral haemorrhage (ICH). However, the association of the...

Authors: Xu Yang, Yan Zhu, Linshan Zhang, Likun Wang, Yuanhong Mao, Yinghui Li, Jinbiao Luo and Guofeng Wu

Increase of blood-brain barrier leakage is related to cognitive decline in vascular mild cognitive impairment

Blood-brain barrier (BBB) breakdown, as an early biomarker for vascular mild cognitive impairment (vMCI), has only been validated by a few studies. The aim of this study was to investigate whether compromised ...

Authors: Man Li, Yue Li, Long Zuo, Wenli Hu and Tao Jiang

A rare cause of stroke: fail-implanted venous port catheter system – a case report

We present the case of a 75-year-old female with acute embolic cerebral infarction caused by a fail-implanted venous port catheter system in the left subclavian artery.

Authors: Mesut Yeniguen, Tobias Braun, Alexander Vlazak, Thomas Umscheid, Martin Juenemann, Tibo Gerriets and Marlene Tschernatsch

Decreased blood CD4+ T lymphocyte helps predict cognitive impairment in patients with amyotrophic lateral sclerosis

ALS patients have changed peripheral immunity. It is unknown whether peripheral immunity is related to cognitive dysfunction in ALS patients.

Authors: Yuan Yang, Dengji Pan, Zhenxiang Gong, Jiahui Tang, Zehui Li, Fengfei Ding, Mao Liu and Min Zhang

Dynamic analysis of CSF1R-related leukoencephalopathy on magnetic resonance imaging: a case report

Colony-stimulating factor 1 receptor (CSF1R)-related leukoencephalopathy is a rare and rapidly progressive leukoencephalopathy characterized by cognitive, motor, and neuropsychiatric symptoms, which is often m...

Authors: Huasheng Huang, Liming Cao and Hong Chen

Retraction Note: In-hospital cerebrovascular complications following orthotopic liver transplantation: A retrospective study

This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12883-021-02175-y

Authors: Li Ling, Xiaoshun He, Jinsheng Zeng and Zhijian Liang

Blood flow response to orthostatic challenge identifies signatures of the failure of static cerebral autoregulation in patients with cerebrovascular disease

The cortical microvascular cerebral blood flow response (CBF) to different changes in head-of-bed (HOB) position has been shown to be altered in acute ischemic stroke (AIS) by diffuse correlation spectroscopy ...

Authors: Clara Gregori-Pla, Rickson C. Mesquita, Christopher G. Favilla, David R. Busch, Igor Blanco, Peyman Zirak, Lisa Kobayashi Frisk, Stella Avtzi, Federica Maruccia, Giacomo Giacalone, Gianluca Cotta, Pol Camps-Renom, Michael T. Mullen, Joan Martí-Fàbregas, Luís Prats-Sánchez, Alejandro Martínez-Domeño…

Correlations among disability, anti-AQP4 antibody status and prognosis in the spinal cord involved patients with NMOSD

Neuromyelitis optica spectrum disorder (NMOSD) is a rare neuroinflammatory disorder of the central nervous system that typically involves the optic nerve, the spinal cord and other specific brain regions. In r...

Authors: Jung Lung Hsu, Ming-Feng Liao, Kuo-Hsuan Chang, Mei-Yun Cheng and Long-Sun Ro

Increasing false positive diagnoses may lead to overestimation of stroke incidence, particularly in the young: a cross-sectional study

Stroke incidence is reportedly increasing in younger populations, although the reasons for this are not clear. We explored possible reasons by quantifying trends in neurologically focused emergency department ...

Authors: Abhinav J. Appukutty, Lesli E. Skolarus, Mellanie V. Springer, William J. Meurer and James F. Burke

Discontinuation of preventive antiepileptic drugs in patients with intracerebral hemorrhage

The risk factors for seizures in patients with intracerebral hemorrhage (ICH) stroke and the effect of seizure prevention by anticonvulsant are not well understood. Limited studies have investigated the risk o...

Authors: Yi-Sin Wong, Chi-Shun Wu and Cheung-Ter Ong

Goal attainment in mobility after acute rehabilitation of mobility-restricting paralysis syndromes with regard to the ambulatory therapeutic level of participation NeuroMoves

A central goal of rehabilitation in patients with paralysis syndromes after stroke or spinal cord injury (SCI) is to restore independent mobility as a pedestrian or wheelchair user. However, after acute rehabi...

Authors: Andreas Hug, Tamara Spingler, Cornelia Hensel, Stefan Fichtner, Tiziana Daniel, Laura Heutehaus, Michel Wensing, Rüdiger Rupp and Norbert Weidner