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  1. Stroke is one of the most frequent causes of death in Germany and the developed countries. After a stroke, those affected often suffer particularly from functional motor restrictions of the upper extremities. ...

    Authors: Stefanie Liebl, Tim Tischendorf, Julia Winterlich and Tom Schaal
    Citation: BMC Neurology 2022 22:194
  2. Cerebrotendinous xanthomatosis (CTX) is an autosomal-recessive lipid storage disorder caused by mutations in the CYP27A1 gene encoding the key enzyme in the bile acid synthesis, sterol 27-hydroxylase. Here, we re...

    Authors: Shingo Koyama, Yuma Okabe, Yuya Suzuki, Ryosuke Igari, Hiroyasu Sato, Chifumi Iseki, Kazuyo Tanji, Kyoko Suzuki and Yasuyuki Ohta
    Citation: BMC Neurology 2022 22:193
  3. Glioma is the most common brain tumor in adults and is characterized by a short survival time and high resistance to chemotherapy. It is imperative to determine the prognosis and therapy-related targets for gl...

    Authors: Lianxin Li, Zhihao Yang, Yinfei Zheng, Zhigang Chen, Xiaoyu Yue, Erbao Bian and Bing Zhao
    Citation: BMC Neurology 2022 22:192
  4. Red cell distribution width (RDW) is a parameter that indsicates the heterogeneity of red blood cell size and could be a prognostic factor in some diseases. Also, intracerebral hemorrhage (ICH) is considered a...

    Authors: Sheida Shaafi, Ehsan Bonakdari, Yalda Sadeghpour and Seyed Aria Nejadghaderi
    Citation: BMC Neurology 2022 22:191
  5. Electrocardiogram (ECG) patterns can change, especially in patients with central nervous system disorders such as spontaneous subarachnoid hemorrhage. However, the association between the prognosis of traumati...

    Authors: Ji Ho Lee, Dong Hun Lee, Byung Kook Lee, Yong Soo Cho, Dong Ki Kim and Yong Hun Jung
    Citation: BMC Neurology 2022 22:190
  6. Postural abnormality is one of the main symptoms of Parkinson’s disease (PD). The erector spinae muscles play an important role in maintaining an upright posture, but the fatigability of the erector spinae in ...

    Authors: Yukihide Nishimura, Hiroyuki Tsuboi, Ken-Ya Murata, Yuta Minoshima, Hideyuki Sato, Yuichi Umezu and Fumihiro Tajima
    Citation: BMC Neurology 2022 22:189
  7. Recent evidence suggests a merging role of immunothrombosis in the formation of arterial thrombosis. Our study aims to investigate its relevance in stroke patients.

    Authors: Angeliki Datsi, Laura Piotrowski, Markella Markou, Thomas Köster, Isabelle Kohtz, Kerstin Lang, Sabine Plöttner, Heiko Udo Käfferlein, Burkhard Pleger, Ramon Martinez, Bogdan Pintea, Roland Fried, Marcus Müller, Rene Chapot and Konstantinos Gousias
    Citation: BMC Neurology 2022 22:186
  8. Since the beginning of the COVID-19 pandemic and development of new vaccines, the issue of post-vaccination exacerbation or manifestation of demyelinating central nervous system (CNS) disorders has gained incr...

    Authors: Lisa Lohmann, Felix Glaser, Gabriel Möddel, Jan D. Lünemann, Heinz Wiendl and Luisa Klotz
    Citation: BMC Neurology 2022 22:185
  9. It is critical for stroke survivors in working age to develop skills and confidence for long-term self-management of physical activity and exercise training to maintain a healthy lifestyle and decrease the ris...

    Authors: Kirsti S. Roaldsen, Charlotte Walter, Johan Gäverth and Ing-Mari Dohrn
    Citation: BMC Neurology 2022 22:183
  10. Congenital absence of the internal carotid artery (ICA) is a highly infrequent congenital incidence and occurs in less than 0.01% of the population; bilateral absence is exceedingly rare, diagnosed below 10% o...

    Authors: Ivana Markovic, Zoran Milenkovic, Bosanka Jocic-Jakubi, Amna Al Futaisi, Kakaria Anupam Kakaria and Yasser Walli
    Citation: BMC Neurology 2022 22:182
  11. Bromine compounds are used in several drugs, including over-the-counter drugs. They sometimes cause intoxication known as bromism. Although the acute neurological symptoms and sequelae of bromism vary, few rep...

    Authors: Masahiro Biyajima, Shunichi Satoh, Takahiro Morikawa, Yuki Morita, Rie Watanabe, Daisuke Matsui, Masataka Konno, Nobutoshi Morimoto, Yuichi Yatsu, Akihito Hirasaki and Hiroyuki Yahikozawa
    Citation: BMC Neurology 2022 22:181
  12. Hereditary spastic paraplegia (HSP) is a group of neurodegenerative diseases characterized by lower-limb spastic paraplegia with highly genetic and clinical heterogeneity. However, the clinical sign of spastic...

    Authors: Jiannan Chen, Zhe Zhao, Hongrui Shen, Qi Bing, Nan Li, Xuan Guo and Jing Hu
    Citation: BMC Neurology 2022 22:180
  13. Disruption of brain functional connectivity has been detected after stroke, but whether it also occurs in moyamoya disease (MMD) is unknown. Impaired functional connectivity is always correlated with abnormal ...

    Authors: Junwen Hu, Yin Li, Zhaoqing Li, Jingyin Chen, Yang Cao, Duo Xu, Leilei Zheng, Ruiliang Bai and Lin Wang
    Citation: BMC Neurology 2022 22:179
  14. Wilson’s disease is a hereditary disorder of copper metabolism resulting mainly in hepatic, neurological, and psychiatric symptoms. Multiple sclerosis (MS) is an immune-mediated demyelinating disease affecting...

    Authors: Katalin Despotov, Péter Klivényi, István Nagy, Attila Pálvölgyi, László Vécsei and Cecília Rajda
    Citation: BMC Neurology 2022 22:178
  15. Regular physical activity is of great relevance in Parkinson's disease (PD). It is part of the inpatient multimodal Parkinson's complex treatment (MKP) in Germany. However, there is often a lack of human resou...

    Authors: Lynn Wagner, Björn Hauptmann, Ann-Kristin Hoffmann, Nicole Jochems, Bastian Schmeier, Andreas Schrader, Thomas Kohlmann and Ruth Deck
    Citation: BMC Neurology 2022 22:176
  16. Many stroke survivors have multiple chronic diseases and complications coupled with various other factors which may affect their functional status. We aimed to investigate the factors associated with poor func...

    Authors: Jing Zhou, Fang Liu, Mingchao Zhou, Jianjun Long, Fubing Zha, Miaoling Chen, Jiehui Li, Qingqing Yang, Zeyu Zhang and Yulong Wang
    Citation: BMC Neurology 2022 22:173
  17. Authors: Derek L. Isenberg, Kevin A. Henry, Adam Sigal, Traci Deaner, Jason T. Nomura, Kathleen A. Murphy, Derek Cooney, Susan Wojcik, Ethan S. Brandler, Alexander Kuc, Gerard Carroll, Chadd K. Kraus, Judy B. Shahan, Joseph Herres, Daniel Ackerman and Nina T. Gentile
    Citation: BMC Neurology 2022 22:171

    The original article was published in BMC Neurology 2022 22:132

  18. Aquatic physiotherapy is becoming a more frequently utilised treatment for people with Parkinson’s Disease (PD). Consumers are increasingly accessing information regarding health choices online, and it is not ...

    Authors: Aan Fleur Terrens, Sze-Ee Soh and Prue Morgan
    Citation: BMC Neurology 2022 22:170
  19. Bupropion, an antidepressant inhibiting the reuptake of dopamine and noradrenaline, should be useful to treat depressive symptoms in patients with Parkinson’s disease (PD). Limited and conflicting literature d...

    Authors: Matteo Vismara, Beatrice Benatti, Gregorio Nicolini, Ilaria Cova, Edoardo Monfrini, Alessio Di Fonzo, Vincenza Fetoni, Caterina A. Viganò, Alberto Priori and Bernardo Dell’Osso
    Citation: BMC Neurology 2022 22:169
  20. HINT1 mutations cause an autosomal recessive axonal neuropathy with neuromyotonia. This is a first case report of coexistence of myasthenia gravis (MG) and HINT1-related motor axonal neuropathy without neuromyoto...

    Authors: Jia Fang, Hui Huang, Qiang Lei, Yingying Luo, Zhengchu Tang, Xiaoliu Shi and Jian Guang Tang
    Citation: BMC Neurology 2022 22:168
  21. Lysophosphatidic acid (LPA) is a common glycerol phospholipid and an important extracellular signaling molecule. LPA binds to its receptors and mediates a variety of biological effects, including the pathophys...

    Authors: Yaya Wang, Jie Zhang, Liqin Huang, Yanhong Mo, Changyu Wang, Yiyi Li, Yangyang Zhang and Zhaohui Zhang
    Citation: BMC Neurology 2022 22:166
  22. As a debilitating syndrome, paraneoplastic cerebellar degeneration (PCD) remains challenging to treat. Further, anti-Yo antibody (directed against human cerebellar degeneration-related protein 2) detection in ...

    Authors: Takeshi Imai, Kensuke Shinohara, Kenji Uchino, Hirohisa Okuma, Futaba Maki, Kiyoshi Hiruma, Yasushi Ariizumi and Yoshihisa Yamano
    Citation: BMC Neurology 2022 22:165
  23. Idiopathic intracranial hypertension is a rare neurological condition among children. Its manifestations vary from mild headaches to loss of vision. Although rare, COVID-19 infection and high dose cytosine ara...

    Authors: Rim Rakez, Wiem Boufrikha, Sana Lakhal, Amel Boughammoura and Mohamed Adnene Laatiri
    Citation: BMC Neurology 2022 22:163
  24. Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy in the pediatric population. The manifestations of this disease include progressive muscle weakness, gait dysfunction, and motor impairme...

    Authors: Gholamreza Zamani, Sareh Hosseinpour, Mahmoud Reza Ashrafi, Mahmoud Mohammadi, Reza Shervin Badv, Ali Reza Tavasoli, Masood Ghahvechi Akbari, Ali Hosseini Bereshneh, Reza Azizi Malamiri and Morteza Heidari
    Citation: BMC Neurology 2022 22:162
  25. Palliative sedation has become widely accepted as a method to alleviate refractory symptoms in terminally ill patients. Controversies regarding this topic especially concern the use of palliative sedation for ...

    Authors: Laura Salzmann, Bernd Alt-Epping and Alfred Simon
    Citation: BMC Neurology 2022 22:161

    The Correction to this article has been published in BMC Neurology 2022 22:188

  26. Operating an aircraft is associated with a large mental workload; however, knowledge of the mental workload of ROV operators is limited. The purpose of this study was to establish a digital system for assessin...

    Authors: Liya Tang, Juanning Si, Lei Sun, Gengsheng Mao and Shengyuan Yu
    Citation: BMC Neurology 2022 22:160
  27. The KHENERGYC trial will be a phase II, randomised, double-blinded, placebo-controlled (DBPC), parallel-group study in the paediatric population (birth up to and including 17 years). The study will be recruiti...

    Authors: Jan Smeitink, Rob van Maanen, Lonneke de Boer, Gerrit Ruiterkamp and Herma Renkema
    Citation: BMC Neurology 2022 22:158
  28. We assess the impact of prevention strategies regarding type 2 diabetes as a modifiable risk factor for dementia and its consequences for the future number of dementia patients in Germany.

    Authors: Anne Fink, Achim Doerre, Ilja Demuth and Gabriele Doblhammer
    Citation: BMC Neurology 2022 22:157
  29. Hemorrhagic transformation (HT) is the most alarming complication of acute ischemic stroke. We aimed to identify risk factors for HT in Chinese patients and attempted to develop a nomogram to predict individua...

    Authors: Keming Zhang, Jianfang Luan, Changqing Li and Mingli Chen
    Citation: BMC Neurology 2022 22:156
  30. It is common for people with persistent spasticity due to a stroke to receive an injection of botulinum toxin-A in the upper limb, however post-injection intervention varies.

    Authors: Natasha A. Lannin, Louise Ada, Coralie English, Julie Ratcliffe, Steven Faux, Mithu Palit, Senen Gonzalez, John Olver, Emma Schneider, Maria Crotty and Ian D. Cameron
    Citation: BMC Neurology 2022 22:154
  31. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is the most frequent autoimmune paraneoplastic encephalitis, and is primarily associated with ovarian teratomas. Here, we report the first case of a pati...

    Authors: Ying Yu, Jun-Li Liu and Dai-Shi Tian
    Citation: BMC Neurology 2022 22:153
  32. The Guillain-Barre Syndrome (GBS), also known as acute idiopathic polyneuritis, is a critical acquired condition associated with preceding nonspecific infection or triggering factors like trauma, surgery, or v...

    Authors: Priyank Patel, Darshil Shah, Chinmay Jani, Jui Shah, Ruchi Jani, Arjun Kelaiya, Jinal Pandya, Harpreet Singh, Omar Al Omari, Dhara Roy, Irmgard Behlau and Ami Parikh
    Citation: BMC Neurology 2022 22:151
  33. Neuronal intranuclear inclusion disease (NIID) is a rare neurodegenerative disease characterized by eosinophilic hyaline intranuclear inclusions in cells in the central and peripheral nervous system. High-inte...

    Authors: Hongfen Wang, Feng Feng, Jiajin Liu, Jianwen Deng, Jiongming Bai, Wei Zhang, Luning Wang, Baixuan Xu and Xusheng Huang
    Citation: BMC Neurology 2022 22:150
  34. We do not yet know whether or the extent to which multimodal therapy changes the health behaviors and health service use of chronic headache patients in the long term. Associations are expected between pain sy...

    Authors: Carolin Donath, Katharina Luttenberger, Christa Geiß, Patricia Albert and Britta Fraunberger
    Citation: BMC Neurology 2022 22:149
  35. A variety of management options (e.g., disease-modifying therapy, lifestyle interventions, rehabilitation) are available for persons with relapsing-remitting multiple sclerosis (MS). Besides coping with the di...

    Authors: Anna Sippel, Jutta Scheiderbauer, Désirée Eklund, Sigrid Arnade, Stephan Schmidt, Ingo Kleiter, Rebecca Morrison, Christopher Kofahl and Christoph Heesen
    Citation: BMC Neurology 2022 22:146
  36. The use of patient reported outcomes measures (PROMs) may offer utility that are important for stroke survivors. This study assessed the PROMIS-10, which contains Mental health (MH) and Physical Health (PH) do...

    Authors: Amber E. Corrigan, Ben Carter, Alexander Smith, Anna Pennington and Jonathan Hewitt
    Citation: BMC Neurology 2022 22:145

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