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  1. The Low-profile Visualized Intraluminal Support (LVIS) device is a self-expanding, nitinol, single-braid, closed-cell device that was recently developed for endovascular embolization of intracranial aneurysms....

    Authors: Quanlong Hong, Wenqiang Li, Jing Ma, Peng Jiang and Yisen Zhang

    Citation: BMC Neurology 2021 21:198

    Content type: Research article

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  2. Neurological outcome and mortality of patients suffering from poor grade subarachnoid hemorrhage (SAH) may have changed over time. Several factors, including patients’ characteristics, the presence of hydrocep...

    Authors: Elisa Gouvêa Bogossian, Daniela Diaferia, Andrea Minini, Narcisse Ndieugnou Djangang, Marco Menozzi, Lorenzo Peluso, Filippo Annoni, Jacques Creteur, Sophie Schuind, Olivier Dewitte and Fabio Silvio Taccone

    Citation: BMC Neurology 2021 21:196

    Content type: Research article

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  3. The effects of BRAFnon-V600E and BRAFV600E on the outcomes and the molecular characteristics of adult glioma patients are unknown and need to be explored, although BRAFV600E has been extensively studied in pediat...

    Authors: Wei Wang, Maode Wang, Haitao Jiang, Tuo Wang and Rong Da

    Citation: BMC Neurology 2021 21:195

    Content type: Research

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  4. The impact of nocturnal disturbance (ND) in Parkinson’s disease on quality of life of patients in Western Countries is increasingly understood. Our study aimed to investigate ND prevalence and its quality of l...

    Authors: Guiying He, Chun-Feng Liu, Qinyong Ye, Zhenguo Liu, Miao Jin, Huifang Shang, Ling Chen, Houzhen Tuo, Hong Jiang, Jifu Cai, Kalpesh Joshi, James Cooper, Lu Zi and Shengdi Chen

    Citation: BMC Neurology 2021 21:194

    Content type: Research

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  5. In patients with multiple sclerosis (MS), the disease’s complications and manifestations affect a person’s ability to function normally and leads to further disruptions in their education, family life, job opp...

    Authors: Atefeh Homayuni, Sedigheh Abedini, Zahra Hosseini, Masoud Etemadifar and Amin Ghanbarnejad

    Citation: BMC Neurology 2021 21:193

    Content type: Research article

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  6. The relationship between the neutrophil-to-lymphocyte ratio (NLR) and poor prognostics in acute ischemic stroke (AIS) patients who receive intravenous thrombolysis (IVT) remains controversial. The purpose of t...

    Authors: Chengbing Wang, Qian Zhang, Mingwei Ji, Jing Mang and Zhongxin Xu

    Citation: BMC Neurology 2021 21:191

    Content type: Research

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  7. The aim of this study was to evaluate the effect of surgical resection and stereotactic biopsy on the complication rate, progression-free survival (PFS) and overall survival (OS) of 70 patients diagnosed at a ...

    Authors: Shiqiang Wu, Junwen Wang, Weihua Liu, Feng Hu, Kai Zhao, Wei Jiang, Ting Lei and Kai Shu

    Citation: BMC Neurology 2021 21:190

    Content type: Research article

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  8. There are numerous barriers to identifying patients with silent brain infarcts (SBIs) and white matter disease (WMD) in routine clinical care. A natural language processing (NLP) algorithm may identify patient...

    Authors: Lester Y. Leung, Sunyang Fu, Patrick H. Luetmer, David F. Kallmes, Neel Madan, Gene Weinstein, Vance T. Lehman, Charlotte H. Rydberg, Jason Nelson, Hongfang Liu and David M. Kent

    Citation: BMC Neurology 2021 21:189

    Content type: Research

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  9. Abnormal hypoperfusion on the surgical side after carotid artery stenting is rare. Neurological deterioration caused by it is deceptive, which can easily lead to misdiagnosis. The mechanism of hypoperfusion ha...

    Authors: Zhizhong Yan, Zhonghua Shi, Yuhai Wang, Chunlei Zhang, Huize Liu, Jin Cai and Xin Zhang

    Citation: BMC Neurology 2021 21:188

    Content type: Case report

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  10. To date, the genetic contribution to Parkinson’s disease (PD) remains unclear. Mutations in the collagen type VI alpha 3 (COL6A3) gene were recently identified as a cause of isolated dystonia. Since PD and dyston...

    Authors: Chong-Yao Jin, Ran Zheng, Zhi-Hao Lin, Nai-Jia Xue, Ying Chen, Ting Gao, Yi-Qun Yan, Yi Fang, Ya-Ping Yan, Xin-Zhen Yin, Jun Tian, Jia-Li Pu and Bao-Rong Zhang

    Citation: BMC Neurology 2021 21:187

    Content type: Research

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  11. When dizziness/vertigo patients presented with balance disorder, it will bring severe morbidity. There is currently lack of research to explore risk factor related balance disorder in dizziness patients, espec...

    Authors: Zhentang Cao, Cuiting Zhu, Yanan Zhou, Yan Wang, Meimei Chen, Yi Ju and Xingquan Zhao

    Citation: BMC Neurology 2021 21:186

    Content type: Research article

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  12. Morvan syndrome (MoS) is a rare autoimmune syndrome associated with antibodies against two kinds of potassium channel proteins, contactin associated protein-like 2 (CASPR2) and leucine-rich glioma inactivated ...

    Authors: Shui-Jing Zhang, Yan-Yan Xue, Hao Yu and Qing-Qing Tao

    Citation: BMC Neurology 2021 21:185

    Content type: Case report

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  13. Choosing a safe disease modifying therapy during the COVID-19 pandemic is challenging. This case series study was conducted to determine the incidence rate and the course of Covid-19 infection in MS/NMOSD pati...

    Authors: Sara Esmaeili, Mohammad Hossein Abbasi, Meysam Abolmaali, Mohammad Mojtahed, Seyedeh Niloufar Rafiei Alavi, Sevim Soleimani, Mahisa Mokhtari, Jaber Hatam, Samaneh Tanhapour Khotbehsara, Mohammad Reza Motamed, Mohammad Taghi Joghataei, Zahra Mirzaasgari and Mehdi Moghaddasi

    Citation: BMC Neurology 2021 21:183

    Content type: Research

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  14. Trigeminal neuralgia (TN) is a severe pain condition and the most common facial neuralgia. While microvascular decompression (MVD) presents an excellent treatment in neurovascular compression cases, percutaneo...

    Authors: Naureen Keric, Darius Kalasauskas, Sophia L. Kreth, Martin B. Glaser, Harald Krenzlin, Sven R. Kantelhardt and Florian Ringel

    Citation: BMC Neurology 2021 21:182

    Content type: Research article

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  15. Camptocormia is common in patients with multiple system atrophy (MSA). The current study was aimed at assessing the frequency of camptocormia and its related factors in MSA patients with different disease dura...

    Authors: Ling Yu Zhang, Bei Cao, Qian-Qian Wei, Ru Wei Ou, Bi Zhao, Jing Yang, Ying Wu and Hui Fang Shang

    Citation: BMC Neurology 2021 21:181

    Content type: Research

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  16. The present study aimed to determine the underlying genetic factors causing the possible Warburg micro syndrome (WARBM) phenotype in two Iranian patients.

    Authors: Raziyeh Khalesi, Ehsan Razmara, Golareh Asgaritarghi, Ali Reza Tavasoli, Yasser Riazalhosseini, Daniel Auld and Masoud Garshasbi

    Citation: BMC Neurology 2021 21:180

    Content type: Case report

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  17. An important cause of hemisensory syndrome is ischemic stroke. However, the diagnostic yield of neuroradiological imaging on hemisensory syndrome is low. Therefore, we aim to describe patients hospitalized wit...

    Authors: Pei Xuan Koh, Joanna Ti, Seyed Ehsan Saffari, Zhen Yu Isis Claire Lim and Tianming Tu

    Citation: BMC Neurology 2021 21:179

    Content type: Research article

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  18. Migraine is a primary headache disorder and is the most common disabling primary headache disorder that occurs in children and adolescents. A recent study showed that paranasal air suction can provide relief t...

    Authors: S. M. R. Bandara, S. Samita, A. M. Kiridana and H. M. M. T. B. Herath

    Citation: BMC Neurology 2021 21:176

    Content type: Research article

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  19. Galcanezumab is a calcitonin gene-related peptide (CGRP) monoclonal antibody (mAb) indicated for the preventive treatment of migraine. While galcanezumab has demonstrated efficacy in patients who did not respo...

    Authors: Dulanji K. Kuruppu, Joshua Tobin, Yan Dong, Sheena K. Aurora, Laura Yunes-Medina and A. Laine Green

    Citation: BMC Neurology 2021 21:175

    Content type: Research article

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  20. The aim of this work is to analyze the reports on cluster headache attacks collected online in the citizen science project CLUE with respect to the effectiveness of drugs taken during the attacks. The collecti...

    Authors: Johannes Drescher, Andreas Khouri, Tina Katharina Amann, Charly Gaul, Peter Kropp, Yannic Siebenhaar and Jörg Scheidt

    Citation: BMC Neurology 2021 21:174

    Content type: Research article

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  21. Isolated anterior cerebral artery territory (ACA) infarction is a rare phenomenon, and is known to have distinctive clinical features. Little is known regarding the clinical prognosis of isolated ACA territory...

    Authors: Hyungjong Park, Young Seok Jeong, Seo Hyeon Lee, Seong Hwa Jang, Doo Hyuk Kwon, Jeong-Ho Hong, Sung-Il Sohn and Joonsang Yoo

    Citation: BMC Neurology 2021 21:171

    Content type: Research article

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  22. The Brief Repeatable Battery of Neuropsychological Tests (BRBN-T) is one of the most sensitive and used measures for detecting cognitive impairment in Multiple Sclerosis (MS).

    Authors: Claudia Sousa, Mariana Rigueiro-Neves, Ana Margarida Passos, Aristides Ferreira and Maria José Sá

    Citation: BMC Neurology 2021 21:170

    Content type: Research article

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  23. The physiological and pathological significance of the arachnoid membrane (AM) is still unknown. In this study, we investigated various characteristics of the AM, focusing on the influence of inflammation and ...

    Authors: Hime Suzuki, Takeshi Mikami, Naotoshi Iwahara, Yukinori Akiyama, Masahiko Wanibuchi, Katsuya Komatsu, Rintaro Yokoyama, Tsukasa Hirano, Ryusuke Hosoda, Yoshiyuki Horio, Atsushi Kuno and Nobuhiro Mikuni

    Citation: BMC Neurology 2021 21:169

    Content type: Research article

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  24. In this study, we aimed to determine the risk association between vitamin D binding protein (VDBP) polymorphism in patients with multiple sclerosis (MS) in a MS biobank and the difference in VDBP serum levels ...

    Authors: Zhila Maghbooli, Abolfazl Omidifar, Tarlan Varzandi, Tayebeh Salehnezhad and Mohammad Ali Sahraian

    Citation: BMC Neurology 2021 21:168

    Content type: Research article

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  25. Neuromyelitis optica spectrum disorder (NMOSD) is associated with inflammatory mediators that may also trigger downstream signaling pathways leading to reduce insulin sensitivity.

    Authors: Zhila Maghbooli, Abdorreza Naser Moghadasi, Nasim Rezaeimanesh, Abolfazl Omidifar, Tarlan Varzandi and Mohammad Ali Sahraian

    Citation: BMC Neurology 2021 21:167

    Content type: Research article

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  26. We report on a patient with an intracerebral hemorrhage (ICH), who showed delayed development of aphasia, which was demonstrated via follow up diffusion tensor tractography (DTT) to be related to neural degene...

    Authors: Min Jye Cho and Sung Ho Jang

    Citation: BMC Neurology 2021 21:166

    Content type: Case report

    Published on:

  27. The clinical characteristics of Parkinson’s disease (PD) differ between men and women, and late- and early-onset patients, including motor symptoms and some nonmotor symptoms, such as cognition, anxiety, and d...

    Authors: Ming Liu, Ya-Jun Luo, Han-Ying Gu, Yi-Ming Wang, Man-Hua Liu, Kai Li, Jiao Li, Sheng Zhuang, Yun Shen, Hong Jin, Jing Chen, Cheng-Jie Mao and Chun-Feng Liu

    Citation: BMC Neurology 2021 21:165

    Content type: Research article

    Published on:

  28. Amyotrophic lateral sclerosis (ALS) is a progressive motor neuron disease with great heterogeneity. Biological prognostic markers are needed for the patients to plan future supportive treatment, palliative tre...

    Authors: Anne-Lene Kjældgaard, Katrine Pilely, Karsten Skovgaard Olsen, Anders Hedegaard Jessen, Anne Øberg Lauritsen, Stephen Wørlich Pedersen, Kirsten Svenstrup, Merete Karlsborg, Helle Thagesen, Morten Blaabjerg, Ásta Theódórsdóttir, Elisabeth Gundtoft Elmo, Anette Torvin Møller, Lone Bonefeld, Mia Berg, Peter Garred…

    Citation: BMC Neurology 2021 21:164

    Content type: Research article

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  29. Self-efficacy concerns individuals’ beliefs in their capability to exercise control in specific situations and complete tasks successfully. In people with multiple sclerosis (PwMS), self-efficacy has been asso...

    Authors: Barbara Seebacher, Roger J. Mills, Markus Reindl, Laura Zamarian, Simone Kircher, Christian Brenneis, Rainer Ehling and Florian Deisenhammer

    Citation: BMC Neurology 2021 21:163

    Content type: Research article

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  30. Patients who have been successfully treated for an aneurysmal subarachnoid hemorrhage (aSAH) often retain multiple health complaints, including mood disorders, cognitive complaints, fatigue, and problems with ...

    Authors: Edith Nobels-Janssen, Inger L. Abma, Wim I. M. Verhagen, Ronald H. M. A. Bartels, Philip J. van der Wees and Jeroen D. Boogaarts

    Citation: BMC Neurology 2021 21:162

    Content type: Research article

    Published on:

  31. The initial CT blend sign is an imaging marker that has been used to predict haematoma expansion and poor outcomes in patients with small-volume intracerebral haemorrhage (ICH). However, the association of the...

    Authors: Xu Yang, Yan Zhu, Linshan Zhang, Likun Wang, Yuanhong Mao, Yinghui Li, Jinbiao Luo and Guofeng Wu

    Citation: BMC Neurology 2021 21:160

    Content type: Research article

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  32. Blood-brain barrier (BBB) breakdown, as an early biomarker for vascular mild cognitive impairment (vMCI), has only been validated by a few studies. The aim of this study was to investigate whether compromised ...

    Authors: Man Li, Yue Li, Long Zuo, Wenli Hu and Tao Jiang

    Citation: BMC Neurology 2021 21:159

    Content type: Research article

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  33. The cortical microvascular cerebral blood flow response (CBF) to different changes in head-of-bed (HOB) position has been shown to be altered in acute ischemic stroke (AIS) by diffuse correlation spectroscopy ...

    Authors: Clara Gregori-Pla, Rickson C. Mesquita, Christopher G. Favilla, David R. Busch, Igor Blanco, Peyman Zirak, Lisa Kobayashi Frisk, Stella Avtzi, Federica Maruccia, Giacomo Giacalone, Gianluca Cotta, Pol Camps-Renom, Michael T. Mullen, Joan Martí-Fàbregas, Luís Prats-Sánchez, Alejandro Martínez-Domeño…

    Citation: BMC Neurology 2021 21:154

    Content type: Research article

    Published on:

  34. Neuromyelitis optica spectrum disorder (NMOSD) is a rare neuroinflammatory disorder of the central nervous system that typically involves the optic nerve, the spinal cord and other specific brain regions. In r...

    Authors: Jung Lung Hsu, Ming-Feng Liao, Kuo-Hsuan Chang, Mei-Yun Cheng and Long-Sun Ro

    Citation: BMC Neurology 2021 21:153

    Content type: Research article

    Published on:

  35. Stroke incidence is reportedly increasing in younger populations, although the reasons for this are not clear. We explored possible reasons by quantifying trends in neurologically focused emergency department ...

    Authors: Abhinav J. Appukutty, Lesli E. Skolarus, Mellanie V. Springer, William J. Meurer and James F. Burke

    Citation: BMC Neurology 2021 21:152

    Content type: Research article

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  36. A central goal of rehabilitation in patients with paralysis syndromes after stroke or spinal cord injury (SCI) is to restore independent mobility as a pedestrian or wheelchair user. However, after acute rehabi...

    Authors: Andreas Hug, Tamara Spingler, Cornelia Hensel, Stefan Fichtner, Tiziana Daniel, Laura Heutehaus, Michel Wensing, Rüdiger Rupp and Norbert Weidner

    Citation: BMC Neurology 2021 21:149

    Content type: Study protocol

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