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Figure 3 | BMC Neurology

Figure 3

From: Focused ultrasound-mediated bbb disruption is associated with an increase in activation of AKT: experimental study in rats

Figure 3

Diminished interaction of ZO-1 and occludin as a result of ultrasound treatment. Rat brain homogenates were prepared from both non-sonicated (-US) and sonicated (+US) regions. A, Western Blot analysis on whole brain tissue lysates (WTL) shows that ZO-1 and occludin protein levels are not changed in response to ultrasound treatment. B, Co-immunoprecipitation of occludin and ZO-1. The amount of Occludin co-precipitating with ZO-1 in the presence of US-treatment is reduced when compared to non-sonicated brains (-US).

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BMC Neurology

ISSN: 1471-2377

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