Table 4 Relationship between selected parameters and change in right-to-left shunt (RLS) in patients with patent foramen ovale and a history of stroke
From: Decrease in shunt volume in patients with cryptogenic stroke and patent foramen ovale
Total patient cohort n = 102 (%) | RLS volume change n = 31 (%) | No RLS volume change n = 71 (%) | P* | P † | |
|---|---|---|---|---|---|
Age (years) median/(range) mean/(SD) | 55.4/(19.7-80.2) 53.3/(15.77) | 44.3/(19.7-74.4) 37.7/(14.85) | 58.9/(21.4-80.2) 57.1/(14.73) | < 0.001‡ | 0.881 |
Sex | 0.04§ | 0.685 | |||
Female | 40 (39.25) | 17 (54.8) | 23 (32.4) | ||
Male | 62 (60.8) | 14 (45.2) | 48 (67.6) | ||
Cryptogenic stroke | 39 (38.2) | 27 (87.1) | 12 (16.9) | < 0.001§ | < 0.001 |
Use of anticoagulants | 40 (39.2) | 21 (67.7) | 19 (26.8) | < 0.001§ | 0.969 |
Atrial septum aneurysm (ASA) | 23 (22.5) | 11 (35.5) | 12 (16.9) | 0.069§ | 0.165 |
Hypermobile atrial septum | 26 (25.5) | 7 (22.6) | 19 (26.8) | 0.806§ | |
Deep vein thrombosis (DVT) | 5 (4.9) | 1 (3.2) | 4 (5.6) | 0.999§ | |
T0-T1 (months) median/(range) mean/(SD) | 10/(5-60) 12.5/(12.1) | 12/(7-60) 15.6/(12.02) | 9/(5-32) 10.17/(8.1) | 0.081‡ | 0.037 |