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Table 5 Factors associated with cryptogenic stroke; subgroup comparison of patients with cryptogenic stroke versus patients with other aetiology

From: Decrease in shunt volume in patients with cryptogenic stroke and patent foramen ovale

 

Cryptogenic stroke

n = 39 (%)

Other aetiologies

n = 63 (%)

P*

P

Age median/(range) mean/(SD)

40/(19.7-65.2) 41.9/(14.5)

63/(34-80.2) 60.4 (11.9)

< 0.001

< 0.001

Sex

  

< 0.001§

0.102

   Female

24 (61.5)

16 (25.4)

  

   Male

15 (38.5)

47 (74.6)

  

RLS shunt size reduction

27 (69.2)

4 (6.3)

< 0.001§

< 0.001

Use of anticoagulants

28 (71.8)

12 (19)

< 0.001§

0.003

Atrial septum aneurysm (ASA)

11(28.2)

12 (19)

0.33§

 

Hypermobile atrial septum (HAS)

10 (25.6)

16 (25.4)

< 0.999§

 

ASA or HAS

16 (41)

19 (30.2)

0.29§

 

Deep vein thrombosis (DVT)

3 (7.7)

2 (3.2)

0.37§

 

T0-T1 median/(range) mean/(SD)

12/(6-60) 14.9/(14.4)

10/(5-45) 11.1(10.2)

0.3

 
  1. *P value calculated in univariate analysis
  2. P value calculated in the logistic regression analysis
  3. § P value based on Fisher's exact test
  4. P value based on two-tailed Mann-Whitney U-test